Connor Doyle, the team's case manager in the first season comes back from the dead, but this time his intentions are not all good.

Case File #67102: ""Possession"" A software designer tells of demons attacking Case File #10103: ""Man Out of Time"" A disoriented man tells of being from the 17th century.

Case File # unknown Donner and Stone are caught in a sinister plot when they investigate a rave club overrun by zombies.

Case File # unknown An old man following three Old West outlaws is actually Axon 30 years in the future, warning his younger self against inventing time-travel.

Case File #321147: ""Perestroika"" The Office of Scientific Investigation and Research's Director of Operations Frank Elsinger orders Case Manager Doyle to lead a team of investigators to Archangelsk in Northern Russia. Having just viewed video footage of a team of Russian scientists examining a creature found frozen in a glacier by two gas plant caretakers, Elsinger does not reveal to Doyle that the last scene of the video showed scientist frightened and pleading for help.

Case File #371-211 When a curator of a museum decapitated by an unknown assailant, the Office of Scientific Investigation and Research starts to investigate.

Case File # unknown A journalist's relationship with a Death Row inmate causes a rare haunting.

Case File #28120: ""The Underneath"" A deadly creature lives in the sewers Case File #52113: ""Phantom Limb"" Strange events follow an accident that claimed a farmer's arm.

Case File #623119: ""UFO Duplication"" Extraterrestrials clone farm inhabitants Case File #847117: ""Clara's Friend"" An apparition communicates with a girl.

Case File # unknown The team's investigation of a woman's precognition of her own death leads to a shocking discovery.

Case File #702134: ""The Hunter"" A werewolf is suspected in cattle mutilations Case File #969121: ""The Healer"" Teen is credited with healing powers.

Case File #631136: ""The Curse"" Death strikes archaeologists who uncovered an Egyptian burial chamber Case File #260122: ""Angel on a Plane"" A mysterious woman safely lands a plane hit by lightning.

Case File #26014: ""Forbidden North"" A humanoid beast approaches a leg-trapped logger Case File #610115: ""Reincarnation"" A man undergoing past-life regression predicts the future.

Case File #104-723 When a huge beast charges out of the woods and rips man's limb, a local police calls in the Office of Scientific Investigation and Research to identify the attacker.

Case File #828-456 The Office of Scientific Investigation and Research investigates the unusual death of a large South American rodent called a capybara at the Windsor Animal Hospice.

Case File #693142: ""Death at Sunset"" A mysterious illness claims its victims at sunset Case File #793144: ""Collision"" The soul of an accident victim possesses the driver who killed her.

Case File # 416-209 The Dean at Braddock University brings the Office of Scientific Investigation and Research in to investigate an incident involving psychokinetic power.

Case File #721-219 When a horrific murder takes place, the Office of Scientific Investigation and Research gets a call to come to a gallery where they find a body strung from the ceiling in the back room, his clothing shredded and his eyes ground into their sockets.

Case File #392-101 Tessler Industries, a video-game giant, is testing one of its new virtual-reality war games at the Office of Scientific Investigation and Research Central Lab. When a woman is knocked to the floor with a very real head wound, Elsinger calls for the O.S.I.R. team to investigate.

Case File #99101: ""Reptilian Revenge"" After an elderly man dies, his pet snakes escape Case File #44114: ""Ghostly Voices"" A voice calls a woman home.

Case File #245-208 The Office of Scientific Investigation and Research investigates several UFO reports in the industry area of Montex Bioengineering.

Case File #567-212 After a blinding light explodes in a hospital room, a blood-covered entity throws the guard out into the hall and the body of a sixty-year-old woman, sentenced to life imprisonment for the murder of a police officer, disappears.

Case File #350-213 The Office of Scientific Investigation and Research is called in to help locate a missing police officer.

Case File #751718 Following a memorial service for Dr. Anton Hendricks the Office of Scientific Investigation and Research team members receive an anonymous phone call informing them that Hendricks is at a nearby hospital unconscious and on a ventilator.

Case File #145345 The Office of Scientific Investigation and Research is called into action when the mutilated corpse of a police detective who gunned down an escaped convict is found in a dumpster.