When a physics professor at a major U.S. university steals weaponized uranium, the team scrambles to find the professor and the missing uranium before it can be used against an important international summit meeting in New York City.

Lives are in danger as the team protects Shelby when she reunites with someone from her past, resulting in deadly consequences.

The team must protect an ex-CIA Agent to take down a cartel kingpin, an assignment that puts all of their lives in danger.

Conor Devlin has plans of his own when he plots revenge and returns to his home country, Ireland; meanwhile, the team unknowingly finds themselves as a pawn in his plans.

Conor Devlin continues to seek revenge as someone from Alex’s past comes back into her life.

The team is in Ireland, and when they finally come face-to-face with Conor Devlin, not everyone comes out alive. And Alex makes a life-changing decision about her future.

Ryan and Alex recruit Owen and Harry to help rescue their friend and defeat The Widow. To help the cause, Owen brings in former agent Jocelyn Turner, who has her own dark past with The Widow.

In tracking down the origin of a deadly strain of tuberculosis threatening Americans, Agent Ryan Booth must go undercover and infiltrate a white supremacist organization; an assignment that threatens the life of another member of the team.

The team is tasked with protecting a scientist who has developed a deadly technology that, in the wrong hands, could have devastating consequences to mankind. Meanwhile, Ryan and Shelby stumble on something personal of Alex’s that signals a possible change in her personal life.

Alex and McQuigg are assigned to protect a prince following the assassination of an emir, but the team soon realizes the killer is closer than they think.

Alex goes undercover with an American military contractor who is believed to have struck a deadly deal with another country; but in the end, it’s Alex’s life that’s on the line.

At Quantico, the NATS team up for defensive driving lessons while tensions between Liam and Drew explode, resulting in shocking admissions and consequences. In the future, Simon grapples with his new reality in the aftermath of what’s transpired. Even though his friends try and help him, it’s uncertain he will ever be the same again.

It’s career day at Quantico as the NATS meet representatives from various FBI branches to help them decide their future paths. In the future, Alex continues to search for the terrorist, and in the process, discovers some familiar faces – including one who knows the terrorist’s endgame.

It’s Alex and the team’s last stand against the Collaborators at the Constitutional Convention, where a new amendment to the Constitution threatens every American’s freedom.

At Quantico, the NATS are given a training exercise that hits too close to home for Shelby. While in the future, Alex finds an unlikely ally in Hannah, as she continues to try and stop the terrorist from striking again.

At Quantico, the NATs look into each other’s background to determine who gets high-level security clearance, and in the process Alex, Shelby and Iris learn some surprising truths about Drew, Will and Caleb. Meanwhile, in the future, Alex contacts Claire Haas (guest star Marcia Cross) in order to find her missing friends and is shocked when she discovers what happened to Cale.

A despondent Clay meets with the President to discuss the future of the task force, but he’s interrupted by the arrival of his brother. Meanwhile, Alex leads an operation to expose the collaborators’ plans to sink the President’s reputation, and she teaches Owen to trust his instincts.

When Owen and McQuigg learn heartbreaking news about family members, the team goes on high alert as they quickly learn nowhere is safe.

With only a few weeks until graduation, the NATS are dispatched to various field offices where Alex and Ryan find themselves working a case together. Meanwhile, in the future, Shelby and Caleb’s relationship takes a turn, and Alex doesn’t know who to trust when she discovers new information about the man she loves.

New CIA recruits run counter-surveillance exercises at The Farm. In the future, Ryan and Raina try to thwart the terrorists' plan to blend in with hostages

At the Farm, Harry is still suspicious of Alex and Ryan, and he’s determined to learn more about their plan, while Leon is recruited for a special assignment by Owen. Meanwhile, in the future, Alex continues to run from the terrorists but faces her toughest challenge yet when the terrorists corner her.

Alex tries to convince Owen of the traitor amongst them. The recruits are tasked with getting an asset out of Germany – but their target has a death wish. In the future, the terrorists resort to new means to gain information from the hostages.

This week the NATS learn how to source information from confidential informants, but when they test their skills in the real world, they soon realize being an agent is not as easy as it seems. Meanwhile, in the future, Alex and a fellow agent find themselves in a life or death situation when they are forced to provide classified information that could result in deadly consequences.

A terror cell tries to infiltrate Quantico, forcing Miranda and Liam to pay a deadly price. While in the future, Alex continues to get instructions from the terrorist – only this time, it’s Claire Haas’ life that hangs in the balance.

At Quantico, the NATS’ current assignment is to learn about human trafficking when Liam and Miranda challenge them to cross the U.S. / Canadian border without passports. Meanwhile, in the future, Simon continues to help Alex try to find the terrorist, but doing so puts his own life in great risk.