When a physics professor at a major U.S. university steals weaponized uranium, the team scrambles to find the professor and the missing uranium before it can be used against an important international summit meeting in New York City.

A diverse group of recruits has arrived at the FBI Quantico Base for training. They are the best, the brightest and the most vetted, so it seems impossible that one of them is suspected of masterminding the biggest attack on New York City since 9/11.

Alex and McQuigg are assigned to protect a prince following the assassination of an emir, but the team soon realizes the killer is closer than they think.

At Quantico, Alex finally receives information about her father and his FBI past, but in the future it’s her mother, Sita, who plays a key role when Liam convinces her to participate in a press conference on national television begging Alex to turn herself in. Also at “Quantico,” the NATS learn the art of profiling and focus on their classmates’ strengths and weaknesses, ultimately challenging their confidence and comradery.

When one of Alex’s friends is framed for a domestic terror attack, they turn to her for help. With an upcoming vote in the House for a Muslim registry bill, the task force realizes this attack isn’t a coincidence. The Collaborators are actively stirring fear to pass the registry, and our team heads to the Hill to turn the votes. Meanwhile, Alex and Owen track down an assassin.

Risking it all, Alex works with Owen to infiltrate the Collaborators. When they begin to test her loyalty, Alex realizes she’s become a pawn in their plan to take down both the President and the task force.

It’s career day at Quantico as the NATS meet representatives from various FBI branches to help them decide their future paths. In the future, Alex continues to search for the terrorist, and in the process, discovers some familiar faces – including one who knows the terrorist’s endgame.

At the Farm, Owen teaches the recruits a lesson on the necessity of betrayal, with a mission of getting the Venezuelan Consul Gabriel Carrera to turn on his country. In the future, Alex is forced to team up with Miranda in order to save the hostages, while President Claire Haas has a plan to end the crisis once and for all.

The team is tasked with protecting a scientist who has developed a deadly technology that, in the wrong hands, could have devastating consequences to mankind. Meanwhile, Ryan and Shelby stumble on something personal of Alex’s that signals a possible change in her personal life.

The team is in Ireland, and when they finally come face-to-face with Conor Devlin, not everyone comes out alive. And Alex makes a life-changing decision about her future.

At the Farm, the trainees learn their next task is to decide on a drone strike, which triggers Alex’s memories of Simon’s sacrifice. Meanwhile, Shelby and Leon’s relationship reaches the next level, and Nimah advises Alex and Ryan not to trust Harry. In the future, Alex questions if she can trust Lydia, leading to combat between the two.

At the Farm, the recruits break into the NSA on a mission to delete all their personal information, but the rogue group within the CIA has other plans. In the future, the hostages strategize an escape via underground tunnels as a set-up to get the terrorists to reveal themselves.

In the wake of the G20 hostage crisis, President Claire Haas assembles an illegal and clandestine joint task force, bringing together Alex and her friends from both the FBI and CIA to unmask a global conspiracy.

A despondent Clay meets with the President to discuss the future of the task force, but he’s interrupted by the arrival of his brother. Meanwhile, Alex leads an operation to expose the collaborators’ plans to sink the President’s reputation, and she teaches Owen to trust his instincts.

With all the collaborators unveiled, the team uses Clay and Maxine’s engagement party to entice them into one place. The mission: turn one against the others. But everyone’s lives are put at risk when one member of the team makes a surprising decision.

The trainees are put through a training drill that tests their stress levels while Alex tries to gather information and get close to Owen. Meanwhile, in the future, the terrorist organization demands a trade, a move that could possibly end the stand-off.

At the Farm, Lydia and Owen teach the group about the necessity of lying and cutting off relationships. Perfect timing for Alex, since she is feeling disconnected from Ryan personally and professionally. In the future, Alex and company attempt to destroy the biological weapon.

The recruits are schooled in the art of seduction, which Alex sees as a perfect opportunity to get closer to Owen, but will it threatens her relationship with Ryan? And in the future, Alex finally gets the answers she’s been looking for about who and what the terrorists are on.

Alex tries to convince Owen of the traitor amongst them. The recruits are tasked with getting an asset out of Germany – but their target has a death wish. In the future, the terrorists resort to new means to gain information from the hostages.

While their newly appointed leader gets familiar with the team of CIA and FBI agents, Owen leads an investigation into the strange world of fake news. But hunting down the publishers of a fake story might lead to deadly consequences.

When Clay is forced to use his fiancée to carry out an operation, the whole team reexamines their personal connections, or more accurately, the lack thereof. Meanwhile, Alex forges an unexpected bond with an asset at the center of a conspiracy, and Harry struggles to find his place on the task force.

After an impossible choice is made, a flood of new proposals shine a light on the final stages of the Collaborators’ plan. Fractured but not defeated, the task force, with the help of some old friends, work to put the pieces together before the Collaborators can enact an unthinkable terrorist attack.

Lives are in danger as the team protects Shelby when she reunites with someone from her past, resulting in deadly consequences.

The NATs learn surveillance by putting it into practice with Miranda and her troubled son, Charlie. Shelby tries to keep Caleb at a distance, but Raina opens the door to a closer relationship with Simon. In the future, Alex is helped when she tries to hack into an FBI computer.

This week the NATS learn how to source information from confidential informants, but when they test their skills in the real world, they soon realize being an agent is not as easy as it seems. Meanwhile, in the future, Alex and a fellow agent find themselves in a life or death situation when they are forced to provide classified information that could result in deadly consequences.