In a somewhat The Three Stooges tribute, Ren Hoek, renowned lover of humanity, and his friend Stimpy decide that they must do everything in their power to help a couple of misfortunates; a woman and her handicapped (headless) son, by building a house for them.

The fire chief was so impressed with Ren and Stimpy's heroic deeds from the first "Fire Dogs" cartoon that he decides to become Ralph Bakshi and move in with them, and to also go out on a bachelor's life to eat pizza; however, Ren and Stimpy are disgusted by his habits.

The story continues showing the fire chiefs bachelor life. Ren and Stimpy promise to look after the fire chief until the day he dies and hence forth move into his apartment where things take a turn for the worse.

Ren and Stimpy enjoy a day at the beach. Ren shows his respect to the superiority of the female form, forcing Stimpy to find succor in the bosom of a large foreign huckster, due to feeling offended by Ren showing attraction to a nearby female. The girls at the beach, however, seem to prefer Stimpy, causing jealousy to rage within Ren.

Stimpy becomes pregnant with Ren's baby, causing Ren to at first abuse, and then respect Stimpy as a partner. Ren is at first disgusted with Stimpy's pregnancy, as he is forced to deal with his incessant loving moments with his child, such as attempting to explicitly eat for two. When Stimpy goes into labour, Ren is forced to start a driveby with other people on the highway. With help from the police, Ren and Stimpy successfully get to the hospital, where their child is delivered by Dr. Horse, only to learn that Stimpy was just constipated, although Mr. Horse does not have the heart to tell the anticipated 'parents' this and so the waste is made to behave like an infant male, and was named "Ricky".

Tired of living inside a homeless man's mouth, Ren and Stimpy move to classy new digs: the inside of a spittoon after Stimpy pools his secret stash of money into it.

In a film noir themed episode, after Ren did something so horrible to Stimpy, it left Stimpy in hysterical grief and Ren in guilt, which he realizes how cruel he can be to his beloved pal and was tried to help something out for him, but Stimpy refused to get help and wanted Ren to help himself, seriously. After a depressing walk from places to places, he walks to the "help" apartment and seeks psychiatric help from Dr. Mr. Horse, to whom he tells his traumatic past, and the roots of his desire to inflict pain upon others.