Rebecca reveals a secret to Sean that reconnects them. Dr. Todd tells Paul and Cathy that the bee therapy did not work. Cathy reconsiders her options. Adam finally shows his softer side in an unexpected way.

Adam surprises everyone when he fulfils one of Cathy's wishes. Cathy's estranged Dad visits her. Andrea gets the opportunity of a lifetime. Sean has mixed feelings about his impending kidney surgery.

Paul seeks support from people at his work place, but gets more than he bargained for. Sean pulls away from Rebecca when it appears she’s getting too serious. Cathy, Marlene and Rebecca have a girl’s lunch at a strip joint -- which unexpectedly influences Cathy’s thoughts about her cancer. Adam meets a girl, Mia, at the bus stop.

Cathy is inspired by Lee’s passing to ring in the New Year in an unexpected way; burdened by financial issues, Paul tries a new tactic with the insurance agency; Adam makes a surprising connection with Dr. Todd.

Dr. Sherman pays a visit to Cathy, who has checked herself into a hospice and is experiencing problems with her new roommate. Adam confronts Paul about his lack of parental guidance. Andrea seeks inspiration from Cathy.

When Cathy's attempt to connect to the people closest to her fails, she signs up for a well-meaning but overbearing cancer support group. Adam rebuffs Cathy's attempts to connect with him, so she decides to put together a dinner party with Andrea, Sean and Daphne. Meanwhile, Paul tries to win back his wife's love with an elaborately romantic gesture. Marlene discovers Cathy's cancer secret in a most unusual way.

For her birthday, Paul surprises Cathy with a party just when Lenny has invited her to an art opening on the Bahamas. At the party, Cathy's brother begins a fling with Cathy's eccentric college friend Rebecca. Meanwhile, picks up Marlene who is wandering around in the backyard.

Cathy’s unexpected visit to Andrea’s home yields many surprises. Later, Cathy seeks spiritual advice at church and while helping around the house. Rebecca calls it quits with Sean in order to reconcile her friendship with Cathy. Adam apologizes to Andrea. Paul sleeps with Tina. Cathy reveals to Paul she has cancer.

Dr. Todd and Cathy go to see the Bee Man to seek non-traditional treatment for her cancer. Paul is overly supportive of Cathy around the house. Sean gives Adam relationship advice about Mia.

Cathy invites friends and family to a Thanksgiving dinner, but a long-hidden secret she brings to light causes trouble.

Rebecca deals with the grief over her miscarriage in an unexpected way which leads Cathy to reconnect with old friends; Andrea's relationship with Myk heats up; Adam is taken by surprise when he finally meets the girl he's been chatting with in an online cancer support group.

As Cathy prepares for her trip to Italy, she receives an amicable call from Lee. Elsewhere, Paul uncovers a secret about Myk while Adam discovers one about Poppy.

Cathy plans Adam's sixteenth birthday party. Andrea struggles settling in with her new room-mate at fashion school. Paul brings in a new assistant.

Sean feels inspired to donate to charity. Cathy upsets Paul when she signs him up to an online dating service. Andrea struggles to impress her tutor, Isaac Mizrahi.

Cathy, eager to try on a carefree, impulsive persona, drains her 401K, buys a convertible and imagines what life would be like if she were Dr. Todd's girlfriend. At his therapist's urging, Paul reignites his passion for rugby. Sean goes to great lengths to knock out a tooth without the help of a dentist. Meanwhile, Adam gets caught stealing and is surprised when Marlene comes to his rescue, until he finds out there are strings attached.

Cathy meets someone new to feel sexy again. Meanwhile, Cathy's eccentric brother Sean tries to keep his building and Adam is caught while watching pornography.

Cathy and Sean hit the open road to visit their dad. During the trip, Cathy tells Sean she has cancer. Sean falls apart at the news, so Cathy pretends it was a big joke. Adam gets drunk while under the supervision of Paul. Marlene finds Adam on the front lawn puking. Marlene will keep it a secret, but Adam is in further servitude to her.

Cathy seeks a second opinion, causing a strain on her relationship with Dr. Todd; Sean learns about his sister's cancer while adjusting to life with a pregnant Rebecca; Adam sees a therapist against his will.

Frustrated at not being able to land a spot in the clinical trial of a new treatment by a respected oncologist, Cathy resorts to supernatural aid; Sean becomes assertive around the house; Adam capitalizes on his classmates' sympathy about his mother's illness.

Cathy is intrigued by Lee, a fellow cancer patient she meets on the first day of her clinical trial; Adam's downward spiral continues with a fight at school and refusal to take responsibility for his actions with Emily; Sean is worried that his new house is haunted.

Lee takes Cathy to a Tibetan doctor to deal with her high blood pressure. Feeling jealousy of Lee, Paul takes Cathy and Lee out for an evening, while Adam interfere with Andrea's date.

Cathy needs a lump on her butt removed and someone to pick her up after surgery. She asks Marlene, who becomes disoriented - so Lenny picks up Cathy instead. Sean moves into Cathy's backyard because he got beat up on the streets. Paul and Adam win the local bathtub races. The event brings Cathy and Paul back together, but at the point of reconciliation, Paul confesses to an indiscretion with Tina and Cathy rejects the reunion. Meanwhile, Andrea breaks into the school and destroys the mural Lenny painted.

Cathy and Paul experience frustrations in bed and with the help of their new house mate Andrea, realize they need to set some patient-caregiver limits; Rebecca is put off by the newly medicated Sean; unsatisfied by his physical relationship with Mia, Adam turns to another girl, Emily.

Adam's shocking indiscretion threatens Cathy's new job as a swim coach; sparks fly between Andrea and Myk, a Ukrainian coworker that Paul is mentoring; Sean seeks advice on taking the "next step" with Rebecca.

Cathy helps Lee check a few items off his "bucket list;" Poppy takes Adam to her high school reunion; a distraught Sean takes issue with his new neighbors.