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The Best Episodes of The Hot Zone

Every episode of The Hot Zone ranked from best to worst. Let's dive into the Best Episodes of The Hot Zone!

In this anthology series, heroic scientists risk all to deal with deadly outbreaks.


Top Episode Highlight

The best episode of "The Hot Zone" is "Arrival", rated 7.7/10 from 624 user votes. It was directed by Michael Uppendahl and written by N/A. "Arrival" aired on 5/27/2019 and is rated 0.1 point(s) higher than the second highest rated, "Cell H".

  • Arrival
    7.7/10 624 votes

    #1 - Arrival

    Season 1 Episode 1 - Aired 2019-05-27

    Dr. Nancy Jaax has one of the most dangerous jobs in the world handling deadly viruses; after a lab accident, she is faced with a possible Ebola outbreak on U.S. soil.

    Director: Michael Uppendahl

    Writer: N/A

  • Cell H
    7.6/10 511 votes

    #2 - Cell H

    Season 1 Episode 2 - Aired 2019-05-27

    Dr. Nancy Jaax and her lab partner, Dr. Peter Jahrling, must take matters into their own hands to determine the source of the virus before it spreads; Dr. Jaax convinces an employee to hand over samples from infected monkeys.

    Director: Michael Uppendahl

    Writer: N/A

  • Charlie Foxtrot
    7.5/10 458 votes

    #3 - Charlie Foxtrot

    Season 1 Episode 3 - Aired 2019-05-28

    When representatives from varying agencies disagree on how to handle Dr. Nancy Jaax's discovery, she realizes there are few protocols in place for containing a deadly virus on U.S. soil; an employee at the monkey research facility falls ill.

    Director: Nick Murphy

    Writer: N/A

  • Quarantine
    7.5/10 410 votes

    #4 - Quarantine

    Season 1 Episode 5 - Aired 2019-05-29

    Dr. Nancy Jaax works tirelessly to find out why the virus is behaving differently than expected in human victims; unforeseen dangers arise at the research facility; Jaax is forced to make a choice between her family and her duty to her country.

    Director: Nick Murphy

    Writer: N/A

  • Expendable
    7.4/10 427 votes

    #5 - Expendable

    Season 1 Episode 4 - Aired 2019-05-28

    An employee at the monkey research facility falls ill, causing Dr. Nancy Jaax to fear the virus has spread to the human population; Jerry Jaax searches for a way to protect his wife; Dr. Wade Carter is obsessed with exposing the dangers of Ebola.

    Director: Nick Murphy

    Writer: Brian Peterson, James V. Hart

  • Hidden
    7.4/10 402 votes

    #6 - Hidden

    Season 1 Episode 6 - Aired 2019-05-29

    A volatile situation inside the research facility comes to a head; Dr. Jaax steps up, but exhaustion threatens the precision needed to sterilize the threat; the press arrives, and neighbors become aware of the danger next door.

    Director: Michael Uppendahl

    Writer: N/A

  • Neither Rain Nor Sleet...
    7.2/10 153 votes

    #7 - Neither Rain Nor Sleet...

    Season 2 Episode 3 - Aired 2021-11-29

    An attack on Capitol Hill sends Ryker and his team to a mail facility that’s become a hot spot for anthrax infections.

    Director: N/A

    Writer: N/A

  • Noble Eagle
    7.1/10 216 votes

    #8 - Noble Eagle

    Season 2 Episode 1 - Aired 2021-11-28

    In Florida, a man mysteriously falls ill and dies. Special Agent Matthew Ryker suspects an anthrax attack - how many others have been infected?

    Director: N/A

    Writer: N/A

  • Hell's Chimney
    7.1/10 161 votes

    #9 - Hell's Chimney

    Season 2 Episode 2 - Aired 2021-11-28

    Ryker’s investigation moves to New York as another case of anthrax occurs. Bruce Ivins begins having suspicions of his coworkers.

    Director: N/A

    Writer: N/A

  • Dream Boldly, Live Fully
    7.1/10 146 votes

    #10 - Dream Boldly, Live Fully

    Season 2 Episode 4 - Aired 2021-11-29

    The FBI learns more about Bruce Ivins’ peculiar past behaviors after an old colleague raises red flags. Ryker and Dani trace the origin of the letters.

    Director: N/A

    Writer: N/A

  • Stentor Roeselii
    7.1/10 137 votes

    #11 - Stentor Roeselii

    Season 2 Episode 5 - Aired 2021-11-30

    All eyes shift to “Mr. Z.” As they start to zero in on a suspect, Ryker and Dani get new assignments - but that won’t stop them from chasing their lead.

    Director: N/A

    Writer: N/A

  • RMR-1029
    7.0/10 145 votes

    #12 - RMR-1029

    Season 2 Episode 6 - Aired 2021-11-30

    With two suspects in question, Ryker’s own beliefs about the case are tested.

    Director: N/A

    Writer: N/A