Nathan James returns home to Norfolk on a mission. With his family now safely aboard the James, Chandler sends his crew in search of their friends and loved ones.

Nathan James is diverted from their mission when they receive a suspicious distress call from a fishing trawler.

Chandler's leadership is put to the test when the ship's propulsion system is in danger of breaking down, the crew becomes overworked and exhausted, and Dr. Scott could potentially lose all of her research on the virus.

Sixteen months after thwarting the coup in America, Nathan James must face yet another global disaster. The question remains, where in the world is Tom Chandler?

Having lost their only lead, the crew of Nathan James continues their search for an item that could save the world. Chandler immerses himself in a mission for revenge.

The crew searches for one of their own as enemies close in on all sides. Slattery is haunted by visions of the past.

The search continues with a reconnaissance mission but things turn violent when an old foe resurfaces.

An undercover mission in the land of the dead leads to disturbing revelations about Dr. Vellek's sinister plans.

After months of fighting, the crew of Nathan James must embark on a dangerous mission to secure important intel that could decide the fate of the war.

The crew members arrive at the Guantanamo Bay military base to collect food, fuel and medical supplies. When they come under attack by escaped Gitmo prisoners, they team up with a gruff private contractor to push back against the offensive.

After returning from the horrors of Nicaragua, panic begins to spread throughout the ship when Lt. Danny Green comes down with a mysterious illness that could be the virus. Losing faith in Rachel and her failing vaccine trials, Chandler now has to deal with a restive crew. If he fails to keep the crew together, the whole mission is in jeopardy.

Nathan James's crew searches for a precious item leading them to a strange place of opulence and violence where they cross paths with a most unexpected ally.

It is all out war as Chandler must face his fears and confront the greatest threat he has ever encountered.

The crew of a lone naval ship try to save humanity when they discover a deadly virus has wiped out most of the population in the series premiere of this drama.

With Rachel close to a breakthrough on her vaccine, she, Chandler and XO Slattery lead a small team into the jungles of Nicaragua on a mission to find monkeys for her vaccine trials. While there, they find much more than they bargained for when they run across a former drug kingpin who will stop at nothing to maintain his stranglehold on his oppressed society. Chandler and his men find themselves in a huge moral dilemma over whether to eliminate this menace or take what they need and continue on with their mission.

Chandler tracks a new threat to Northern Florida. Meanwhile, Rachel comes across a secret formula that her mentor, Dr. Hunter, had been perfecting.

With an enormous storm on the horizon, Nathan James must navigate an equally terrifying threat in order to make it to safety.

The crew faces a new foe targeting Rachel and her research, leading Chandler to engage in a series of dangerous strategic maneuvers.

Still trying to piece together Dr. Hunter's lost formula, Rachel grapples with her sworn enemy's presence on board the Nathan James.

CNO Tom Chandler is sent to Asia to investigate a possible mutation of the Red Flu. Captain Slattery and his crew deliver cure to Southeast Asia but there may be an unexpected threat in the region.

Chandler confronts his enemy — and his personal demons — in a final showdown, with the fate of humanity on the line.

After picking up a distress call near Jamaica, Chandler and a small team stage a rescue attempt. But a surprise attack leave Chandler and Tex stranded at sea. Slattery and the crew search desperately to find their lost at sea Captain and his comrade, hoping to do so before their enemies beat them to it.

The crew of Nathan James discovers that hospital ship USNS Solace was sent to sea to wait for Dr. Scott's cure. Captain Chandler sees an opportunity to add another ship to their fleet while Rachel is eager to find a lab better equipped to replicate the vaccine. When Solace fails to respond to radio communications, Chandler and his team board the ship...and come face-to-face with an unexpected enemy.

With a small group of survivors from Solace in tow, Chandler and his crew square off against an enemy of the most dangerous kind - a nuclear-powered submarine led by rogue British naval officers, Sean and Ned Ramsey. XO Slattery interrogates a captured mercenary from the hospital ship in an effort to extract information on the sub and its mission. As Nathan James engages in a perilous game of cat-and- mouse, the truth about the mercenary sub unfolds.

Rachel is hard at work on a new, more efficient version of the cure while Alisha decodes a message found on a recovered cell phone.