As preparations get under way for the Royal's charity ball, Ken Hopkirk is forced to rescue the band hired for the evening when their van breaks down en route. Meanwhile, Dr. Weatherill faces a traumatic time as one of her patients discovers she has contracted syphilis and Dr. Ormerod resolves to move on when it emerges that his wife will not recover from her coma.

A frantic mother and father bring their daughter to the Royal for whooping cough treatment, and Cheriton is shocked to hear the girl hasn't been vaccinated because of her parents' fears of the side-effects. Tragically, the youngster dies - leaving the worried staff to cope with an influx of children in need of immunisation.

Ormerod rushes to help following a boating accident, but realises he's been sent to the wrong location, and when he finally arrives at the disaster scene, his efforts to save a man's life prove futile. On returning to the hospital, he angrily chastises Lizzie for the misinformation - only to realise he was too hasty in blaming her. Can he make amends? Meanwhile, PC Ventress comes to the Royal with two men who had been fighting over a girl, and one promptly collapses due to a brain haemorrhage. Weatherill faces a testing time when she helps deliver a baby which is tragically stillborn and nurse Meryl reveals she suspects she may be pregnant.

Sister Brigid has a crisis of faith over a mother whose life is in danger. Family secrets are exposed when a hunting trip ends in tragedy, and Ken and Harper clash over the hospital laundry.

Gordon struggles to cope following the coach crash which left his wife horrifically injured and turns for comfort to colleague Jill, who tries to persuade him to take time off work. Meanwhile, a woman arrives at the Royal requiring an emergency hysterectomy following an illegal abortion, and pleads that the whole affair be kept secret from her fiance, and Greengrass is shocked to discover he has a long-lost daughter.

A teenage boy is brought into the Royal having fallen from a cliff, but it soon emerges that the incident was a suicide attempt as evidence of extreme depression comes to the surface. Cheriton contacts the youngster's psychiatrist but is taken aback when electroshock therapy is suggested as a form of treatment, so ventures to the family home to recommend an alternative — only for tragedy to strike. Meanwhile, a hypochondriac causes chaos at the hospital when she insists her dog be treated following a snake bite, and a heart-to-heart between Weatherill and Ormerod leads to a passionate kiss.