Arthur is nursing The Tick, who is infected with a most uncommon cold!

A night at the local superhero bar turns explosive thanks to the evil midnight bomber!

See Arthur face off against the most evil sock puppet in organized crime.

When Arthur goes off on a date with Carmalita on Hobby Night, Tick builds himself a new sidekick - Little Wooden Boy. Swiss Commandoes are after the notebook of Dr. Vahtoss, Carmalita's father and the inventor of Arthur's flight suit. And Blowhole, a giant long-distance running whale, accidentally swallows everyone, forcing the Tick to light up Little Wooden Boy to cause Blowhole to choke them up. Yep, just another day in The City...

The Tick is sent into space to blow the ""CHA"" out of the Moon from when Chairface tried to write his name in the moon. He blows the letter C up while he's inside it and gets sent through space. While in space he comes across a fantastically large alien named Omnipotus. The Tick befriends him and becomes a janitor on his body. But Omnipotus is an eater of planets and plans to eat the Earth when they get to it.

The Mustache, a U.S. secret weapon, escapes from the lab and tries to team up with its counterpart, the Russian Beard. In hot pursuit are Jim Rage and the Ladies of Project: Shave, so the Mustache takes refuge on the Tick's lip. Meanwhile, Dinosaur Neil and Dot plan for their marriage.

Sewer Urchin battles his arch enemy, the Sewer Czar, earning the respect of his fellow superheroes.

Betty, Queen of the Ants, leads the ants of the City in revolt - it loses its major defender when the Tick is thoroughly creeped out and checks himself into Captain Sanity's Superhero Sanitarium. Betty and her minions capture the other heroes and lock them up in a giant People Farm, then collect enough glass to build a giant magnifying glass and use sunlight to fry them. Fortunately the Tick regains his (normal) sanity in the nick of time and saves the day.

The Tick is chosen for a superhero exchange program - he travels to Antwerp while Eclair comes to The City. While the Tick and Eclair's sidekick Blitzen foil a kidnap plot against the King of Belgium, Arthur and the lightning-blasting Eclair must defeat the Breadmaster and his Gingerbread men.

A small-time bank robber in a stolen Santa Claus costume is chased into an electric billboard, gaining miraculous powers. He becomes Multiple Santa, a villain able to create electric clones of himself. The Tick, Arthur, and their superhero friends are called upon to rid The City of this Christmas menace.

An alien race called the ""Whats"" kidnap the Tick and Arthur to attempt to thwart their nemesis' the ""Heys"" from destroying the universe.

The Terror sends his so-so villainous son Terry to recover his Desire-O-Vac - he lost it in an epic battle against the Decency Squad decades ago. The Tick is there listening to the old-time Squadders' tales and eventually gets involved, but it's a rebellious Terry and the aged Decency Squad members who save the day.

Dinosaur Neil, palaeontologist, curator of Dinosaur Grotto and one-time giant city-destroying mutant, is marrying Arthur's sister Dot. Chairface Chippendale, The Breadmaster and El Seed have other plans, though - plans which involve tampering with Neil's medication, man-eating bouquets, exploding wedding cake, and The Indigestible Man. And as if that wasn't enough, Neil's best man is... The Tick! It's up to our blue hero, Arthur and Dot to save Neil, with the aid of a submarine and 1,400 pounds of pungent raw meat...

The Deerfield Aztecs, a baseball team, crashed in Mexico and formed their own lost tribe of real Aztecs. They track their missing shortstop, Carmalita (Arthur's girlfriend) to America but grab Arthur instead. When the Tick and Carmalita pursue, the Aztecs and their leader Wally unleash ""Speak"", some kind of lowly animal that they intend to wed Arthur to. Tick takes a shine to ""Speak"" (as he names him) and he defeats the Aztecs and rescues Arthur.

Arhtur is annoyed at his failed attempts to lose weight and dismayed at how much of a wimp he is. When he and Tick defeat a villain named Evil, Arthur takes Evil's strength-enhancing belt. When Arthur wears it, he gains confidence and likes seeing himself with a muscular physique. While dating Carmalita, Arthur picks a fight with two guys to show his new strength and confidence. The Tick is called in to end the fight and he tangles with Arthur. In the end, Arthur must get rid of his strength belt to save his and Tick's life. Arthur realizes the addiction the belt gave him and tosses it away so that he can be himself.

A villain who can animate furniture and make it do her bidding falls in love with Die Fledermaus and tries to take over The City, with hilarious consequences and sexy results.

The Tick and Arthur are chosen to teach Superhero School and a classroom of unlikely heroes. They must rush into action to take on Uncle Creamy, a corporate mascot turned into a evil ice cream cone who strikes out at the company who made him. Meanwhile Uncle Creamy II attacks, trying to kill Uncle Creamy before he tells the heroes what the company is up to.

Tick and Arthur reveal their superhero origin story.

The Breadmaster is an evil baker that uses baked goods to terrorize The City.

A camera crew follows the Tick and Arthur around for a day of crime fighting as they do battle with a unique villain.

The Tick and Arthur end up in the distant past and uncover a diabolical plot by the Hotel Manager, a man from the future using prehistoric man as staff for his Hotel at the beginning of the universe. They manage to defeat him and free man's ancestors from a life of low-paying minimum wage jobs.

El Seed hopes to take over the city by bringing all of the plants and trees to life.

While Charles's parents discuss child-rearing with no punishinment, their Branchild is ending Earth!

A clown with a major hang-up. Laugh at him and you'll pay the price.

The Tick and Arthur are invited to the Mad Scientist Fair to help Dr. Vahtoss try out his mind-transference device. Hilarity ensues when the two switch bodies. Chairface Chippendale moves in to try and steal the device and soon everyone is switching with everyone.