A disabled Florida woman is cared for by her sister in relative peace for four decades until a life-changing event decimates their relationship, and the result is murder.

The Good Sister

In Kerrville, Texas, a long-simmering family feud takes a deadly turn when suspicions and tempers take over. It's a decades-long drama with a shocking ending that nobody sees coming.

Breaking Point

The black sheep of the family has spent a lifetime in the shadow of her prodigal younger sister. As the relationship with her mother takes a turn for the worse, things build to a boil that will leave one family member dead.

Go to Daddy

Charity seems like your typical teenager - she's a popular cheerleader with good grades and and works at the local pizza parlor. But to her mother and sisters, Charity is possessed by a demon that needs to be dealt with.

The Demon Inside

A cold-blooded murder in a devout prayer group triggers a bizarre investigation in Oregon. As police uncover the unlikely culprits pulling the strings, chilling beliefs are brought to light.

The Naked Truth

After years of struggling with mental health issues, Janece Cook moves in with her elderly parents. But when the family patriarch commits suicide, her younger sister is determined to sever Janece's ties with the family.

The Torment

When 16-year-old Stephanie Santerre goes missing, everyone in her life falls under scrutiny. An emerging web of lies and deception leaves investigators to puzzle out the sordid truth.

My Sister's Keeper

Two sisters, with little in common, cope with their overly protective mother in very different ways and with very deadly consequences.

House Rules

A custody battle turns deadly as twin sisters craft a complicated, cross-country conspiracy to eliminate the one person standing in their way - as the children look on in dismay.

Smokey Mountain Murder

A childhood friendship turns into an adult romance that ends in murder.

The Bloodiest Bond

When a philanderer is reported missing, police suspect foul play, focusing on the man's wife as well as her best friend in the world, her sister.

Blood in the Snow

Deep-seated envy between two pregnant sisters leads to a twisted murder plot in an unsuspecting Midwestern town. This unspeakable crime leaves the Merrifield family destroyed forever.

Bye Bye Baby

Tensions arise when a new addition to the Finkle family shakes up their peaceful dynamic, but no one could predict the fatal and gruesome results to come.

Daddy's Girls

A mysterious letter surfaces and contains a shocking twist in a homicide investigation. An entire family is impacted by the bombshell police uncover.

The Letter

The Beck twins spend their entire lives side by side in the same house, until the day one of them decides that she's had enough.

Dead Ringers

Two adopted sisters are inseparable until the social pressures of high school and bullying drive a wedge of violence between them.

A Shot in the Dark

The accidental drowning of their two children strains Lonnie and Betty Jo Fowler's marriage to the breaking point. But after reconciling and moving closer to family, a sister-in-law's suspicions turn violent.

Drowning in Despair

A well-intentioned social worker goes missing after becoming involved with two sisters raising children in a trash-ridden house.

Murder is a Filthy Business

When her husband cuts her off financially, Diane Hart turns to her older sister for help; the sisters come up with a deadly plan to get at the money Diane feels she deserves.

Murder Has Two Faces

One daughter's tragic murder rocks a dysfunctional family's world. A second daughter descends into madness by the death, coupled with a ferocious custody battle that drives her into a homicidal rage.

A Song For Sarra

The Plummer sisters' tight relationship unravels with a series of suspicious arsons and a missing inheritance. Then one sister falls ill, while her estranged sibling coldly witnesses her slow, painful death.

Her Own Medicine

A hit-and-run car accident might not be an accident, after all.

The Old River Road

Cold as Ice

The Patio Door

The most outrageous and provocative crimes ever committed by sisters, who sometimes work together and sometimes turn against each other.

All Episodes of Twisted Sisters

Season 1

Breaking Point

Season 1 Episode 6 - Aired 10/8/2018

The Naked Truth

Season 1 Episode 1 - Aired 9/3/2018

My Sister's Keeper

Season 1 Episode 3 - Aired 9/17/2018

Bye Bye Baby

Season 1 Episode 2 - Aired 9/10/2018

Daddy's Girls

Season 1 Episode 4 - Aired 9/24/2018

The Letter

Season 1 Episode 5 - Aired 10/1/2018