We take you to some of the most unique eateries in New York City that are serving up their twist on comfort food staples. A rowdy meatball joint on the lower east side, a bustling restaurant serving knockout chicken and waffles in Brooklyn, an eco-friendly hot dog haven where the chef makes the condiments from scratch, and a burger and fries shack in the middle of the city that boasts lines down the block every day.

We'll find out why the burger at Minetta Tavern is the most talked about burger in town and what makes this eatery top everyone's reservation hot list. Plus, starred chef Daniel Boulud takes us inside his first downtown eatery for an international tour of his house-made sausages. And, there's nothing more unique than a restaurant that specializes in every kind of grilled meat imaginable - and it's all you can eat.

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These are places where the drink list may be long, but the dining is the real reason to visit. We meet the chef who brought the tradition of gastropubs over from England and experience her nose-to-tail cooking. Then, a gastropub that serves American favorites like hot dogs and tater tots, but this fare is far from the ordinary. Plus, a traditional German-style beer hall that boasts the best home-made charcuterie in town.

The meals are hand-held at these hotspots, but the unique flavors are the big attraction. Authentic Mexican cuisine pioneer Rick Bayless celebrates Mexico's most beloved street food and snacks, while two brothers bring decadent Italian toasts to one of New York's hippest neighborhoods. A Top Chef winner turns traditional eastern-european cuisine on its head with inspirations from his own Scottish-Israeli heritage. And a former fine dining chef feeds the need for cheese on the streets of LA - one gourmet grilled cheese sandwich at a time.

Classic American fare gets the royal treatment at these extraordinary spots. Heavy-Metal inspired burgers piled high with the works, mouth-watering, stick-to-your-ribs barbecue in Brooklyn, a downtown L.A. hotspot taking American desserts to new heights, and the creamiest, craziest ice cream creations you can fit on a cone.

We take you on a gastro-tour of some of the most adventurous efforts in dining today. From a 9-course underground dinner party in Chicago to a double-decker bus serving gourmet comfort food on wheels, to an all-out Beef Seven Ways feast, these unique culinary adventures are not to be missed.

Imagination roams free at these amazing dining spots, where food and fantasy meet. A pioneer chef in molecular gastronomy pushes the boundaries between food, science and art at WD-50, while culinary innovator Jose Andres offers up a collection of magical dining experiences entwined in an artistic Spanish-inspired setting at The Bazaar. And get an inside glimpse at an exclusive Hollywood speakeasy, serving "prohibition tea" and tea-inspired tastings to L.A.'s most elite eaters.

Take a tour of the most unique places and spaces in dining today - from a food truck serving the most delectable Korean/Mexican dishes on four wheels, to a LEED-certified bowling-alley-cum-music-venue boasting it's own special Blue Ribbon menu, to a locally-inspired private farm table dinner requiring reservations up to a year in advance.

Classic Italian meets passion, authenticity and innovation at these noteworthy restaurants. Vetri has been called one of the best Italian restaurants in America, presenting simple, fresh, authentic Italian dishes in utterly unique. Chef Nate Appleman, brings gourmet savory and dessert pizzas to Pulino's from brunch to late night, and Porchetta's Sara Jenkins brings this Italian street-food to a tiny Lower East side store front, where "drop-dead-delicious" pork draws a steady stream of the hip and hungry.

Indulge your weekend cravings at some of the most unique brunch spots from the nation's capitol, to New York, to the Pacific Northwest. Check out a do-it yourself pancake house, savor Italian versions of brunch favorites, dive into over-the-top sweets, and treat yourself to an upscale brunch you won't forget.

These are eateries that serve food late into the night, and they are definitely worth staying up late for.

We'll take you from coast to coast to taste the most unique cupcakes in the country. Indulge in artisanal cupcakes paired with beer and wine, stuff yourself with custard-filled cupcakes, take a trip to the frosting bar and create your own unique combination, and take your cupcakes to go...

We highlight some of the most unique takes on southern home cooking. From fiery hot chicken in Brooklyn, to southern heavies that are actually light and healthy, to a decadent southern Sunday brunch in Portland, and a "Meat and Three" supper in Atlanta you'll want every night of the week.

Come see what's between the buns at these burger joints that are taking the American classic to the next level. Whether it's with foie gras in Philly, pimento cheese in Atlanta, umami in Los Angeles or truffles in New York.

If you like ice cream, you will be wowed by these unique treats. How about bourbon and corn flakes flavored scoops at Humphry Slocombe? Or the sweets at Sweet Rose Creamery where everything from the cones to the chocolate chips are made from scratch? And don't forget to visit the Dairy Godmother for unique ice pop flavors like grilled pineapple and pink peppercorn.

We'll show you unique sandwiches from across the country and the people who make them so special. A Jewish Deli in New York with roots with Montreal is serving up their signature smoked meat. Classically trained French chefs in San Francisco are upgrading some Asian classics while just down the street a hands-on chef from Massachusetts is making everything from scratch. And in Portland, three friends from North Carolina are turning out the best biscuit sandwiches in town.

Give in to your chocolate cravings at these hotspots that make everything you could ever desire in chocolate! From gourmet confections like chocolate fleur de sel toffee, nostalgic baked treats like whoopie pies, outrageous hand formed chocolate salamis, and chocolate sea salt crostatas. These handmade chocolate treats will tantalize your tastebuds.

These unique eateries churn out some of the best street foods on the planet. Enjoy authentic Thai dishes in Portland. Feast on succulent chicken and porchetta from a rolling rotisserie truck in San Francisco. Bite into coconut jam sandwiches in Los Angeles and grab a Belgian waffle to go in Portland.

Farm to table dining has certainly swept the nation, but these locations take the idea of farm to table to the extreme. At Blue Hill at Stone Barns, they take farming to a scientific and educational level, and then turn the fruits of their labor into fine dining. At Dinners at the Farm, you dine under the stars on the very farm where the ingredients were picked moments ago. And at Ubuntu, where the plates are like works of art, even meat eaters eat their vegetables...and love it.

Check out creativity at its best at these eateries where it's not just about the food, but also the unique drinks. A java boutique where coffee drinks come in the most unique flavors; A brew pub where the beer menu reads like a book and the ales are used in the dishes too; to Mexican eatery shaking up margaritas and mezcals in unusual combinations, and a prohibition style gin joint where even the ice is carefully crafted.

Everything is better with cheese, and these restaurants will show you why. Take a tour of a cheese cave and enjoy a world-renowned fondue and cheesecake in New York. Find out how many cheeses can fit into one macaroni and cheese dish in Connecticut. And enjoy some of the most unique and sought-after grilled cheese sandwiches in San Francisco.

Small plates with big flavors are the attraction at these restaurants. Enjoy Peruvian seafood specialties by the bay in San Francisco, Mediterranean favorites in Los Angeles, new twists on low country classics in Charleston, South Carolina, and Japanese grilled bites in New York.

Roll up your sleeves and get ready to dive into some of the most unique seafood dishes. A traditional oyster roast and seafood boil prepared right on the water in Charleston, South Carolina. A New York City restaurant that features twenty-five different mussel pots, complete with French fries and bread to sop up all the unique flavors. A cozy restaurant in the heart of Boston's North End where you can get two different lobster rolls and lobster spaghetti. And Montreal, where a Texas chef adds global flavors to his seafood menu.

Find out where all the foodies go to fill their bellies with the best dumplings and noodles in Chicago. Take a seat at the bar and be dazzled by Japanese robata-style cooking in New York City's East Village. Sample creative Chinese cooking like tea-smoked chicken, salt and pepper shrimp and steamed duck egg custards in North Carolina. And step inside a funky retro diner in Boston where a husband and wife team are serving up innovative Cantonese and Taiwanese dishes.