Tara re-emerges but the task now is to repair broken family relationships, particularly with Marshall who is fed up with it all. Rather than go into a local mental health facility, she decides to follow Dr. Hatteras' advice and see a specialist in Boston. Neil and Charmaine are moving to Houston and offer to take Marshall with them. Kate receives an offer to move to St. Louis. As a new family dynamic emerges, everyone contemplates and wonders what the future may hold.

On the day of Charmaine and Nick's wedding, long-held secrets come to light, while Kate and Marshall accidentally make a discovery of consequence.

Her psychology professor humiliates Tara when she transitions in his class. Meanwhile, Kate considers giving English lessons in Japan and Max gets a business offer.

Tara and Charmaine are rushed to the hospital in the same ambulance, where Charmaine declares her baby off limits to her crazy sister; Tara attempts to make a deal with her alters, which intrigues her Abnormal Psychology professor; Marshall, Lionel and Noah put Charmaine's empty house to some creative uses; Kate is embarrassed to confess that she backed out of going to Japan.

Tara tries to drop her Abnormal Psychology class but instead receives an intriguing pitch from her instructor, Dr. Hattaras; Charmaine and Neil find parenthood a struggle but still refuse Tara's help; Max finds himself at odds with his boss at his new job; Kate prepares for flight attendant training; Lionel catches Marshall with Noah, jeopardizing their student film project.

Max and Marshall return home from New York to bad news on all sides. Max learns of the new alter, Bryce, but a highly medicated Tara assures him all in under control. Marshall learns that a close friend has been killed in an accident. Tara offers support, which he gladly accepts, but on the day of the funeral Bryce emerges and apparently will not go away. It's all too much for Kate and Marshall who look to strike out on their own.

Needing a break from real life, Kate and Tara head out on an impromptu road trip. Max uses this time away from Tara to search for answers about her past. That night, Tara and Kate get into an argument causing Tara to transition into “T.” “T” heads to the nearest tattoo parlor and Kate tries to stop her before she makes a permanent mistake.

Tara decides to check into an in-patient facility that specializes in dissociation. There, Tara meets a new doctor, Dr. Holden, a charismatic expert, who pushes her to recover lost memories. The facility has support groups for significant others too, but Max is wary. As Tara tries hard to delve into her past, her alters are resistant to allowing the truth to surface, and Max learns he’ll have to be stronger than ever to help Tara take the next step in her recovery.

Max is worried when Tara returns to college to finish her college degree. Meanwhile, Charmaine with a baby on the way is avoiding a commitment to Neil, Kate tries to figure out a plan for her future and Marshall and Lionel sign up for a filmmaking class.

With Max and Dr. Holden’s help, Tara meets face-to-face with an important person from her past. This meeting, while difficult, leaves Tara feeling conciliatory and expansive. Marshall finally reconciles with Tara and gives her his full support. The family, now reunited for the first time since Tara checked into the hospital, decides to partake in a family tradition – bowling but as Tara looks around at her family, she realizes she’s not who she is in spite of her alters, but BECAUSE of them.

The stress of juggling school and Charmaine's baby shower causes Tara to transition, with negative consequences for Charmaine. To sell the family business, Max must get the approval of his eccentric mother. Kate meets a flight attendant who inspires a new idea about her future.

The discovery of Tara's new dangerous alter makes Dr. Hattaras and Tara consult another professional. Marshall finds out that his short film hurt his father's feelings and Charmaine connects with "chic moms," while Kate tries to make her relationship with Evan work.

A tornado brings some long-covered secrets to light when Tara's alter Shoshana takes over.

An upcoming visit from a social worker has its effect on Max. Disapproving Kate's friendship with Lynda, Tara interferes while Neil learns that Charmaine is pregnant.

Tara and Charmaine discuss Tara's childhood memories with their mother and Max holds an open house after re-modeling their neighbor's house.

Tara and Charmaine pay a woman who appeared in Tara's memories a visit, while Kate tries to change herself for her new and much older boyfriend.

The family is under the impression that Tara’s parents, Bev and Frank, are visiting to celebrate Charmaine’s birthday but when Frank approaches Max about taking the kids to live with them, Max does everything he can to prevent Tara from switching. At the party that night, Tara learns of her parents’ plan and is hurt that they think she is an unfit parent. Sweeping her feelings under the rug, she remains calm however, later that evening, Max wakes to find something that changes everything.

When Bryce takes over, Tara's new alter threatens to destroy the whole family. When Tara's other alters disappear one by one, Max decides to fight off Bryce before it's too late for Tara.

Tara realizes her alternate personalities are emerging again, but keeps it a secret. Newly engaged Charmaine asks to move in with Tara and her family. Max decides to take on a new project by buying the neighbor’s house to flip it. Kate meets a mysterious older woman, Lynda (Viola Davis), while Marshall begins a new relationship… with a girl

Tara motivates Max to relive his old rock band Beaverlamp. Meanwhile, a depressed Dr. Hattaras makes her take a break from their therapy sessions and Marshall and Noah interview Max for their film festival project.

Charmaine has decided to get her breasts re-done and has asked Tara to be her caretaker while she recovers. Kate gives Marshall Love advice, telling him to play hard to get with Jason. When Charmaine wakes after her surgery, she is surprised to see “Buck” at her bedside, not Tara. While “Buck” takes care of Charmaine, she comes to appreciate him in a way she never has before.

Max has his hands full while “Alice” is out again. Marshall fears Jason’s father knows about his crush on Jason. The boys grow closer, albeit platonically. Max decides to embrace his time with “Alice,” even though he misses his wife.

Season two opens with a bang as the Gregsons' neighbor commits suicide and the family unexpectedly is given responsibility of the house. Now well and dissociation-free for several months, Tara sets out to make new friends with Max's help. Marshall struggles to fit in at school while Kate lands a new job. Nick pops the question to Charmaine

The family discovers the truth -- Tara’s alternate personalities are back. Buck’s actions have brought serious consequences that unleash a new side of Max. Neil finds out about Charmaine’s engagement. Marshall and Courtney begin to experiment as Kate grows closer to Lynda.

Tara sets out to find a new therapist as Max struggles to come to terms with Buck’s affair. Marshall and Courtney take their relationship to the next level. Tara and Max disapprove of Kate’s friendship with Lynda. Charmaine tells the family some big news. A new alternate personality is born.