The 2002 slaying of a Brunswick, N.Y., couple is investigated.

The 1997 murder of Henry Caneva and the investigation that nabbed his killers are discussed.

The hunt for burglars who killed a Lafayette, La., man the day after Hurricane Katrina hit the Gulf Coast is chronicled.

The 1992 murder of Angel Ormston and the investigation that nabbed her killer are discussed.

The 1991 murder of a young girl in San Diego is investigated.

A 1993 triple homicide results in the deaths of a Kentucky veterinarian and his family.

Investigating a 1997 quadruple murder in Bartow, Fla.

A judge and his wife are slain in their home, and the suspects range from common criminals to politicians.

A 1997 murder in a California town is investigated.

The 1980 murder of a Colorado teenager is investigated.

Shortly before Thanksgiving, a Philadelphia suburb is rocked by the murder of 67-year-old Alice Hufnagle.

The 1995 death of a Chicago woman whose body was found on a Wisconsin highway is detailed in the Season 4 premiere.

The 1980 murder of a California businessman's wife is detailed.

When a first-year college co-ed turns up raped and murdered, it takes a freshman cop to beat the odds and catch a killer.

The crimes and apprehension of the Texas Bathtub Killer are discussed.

A former Marine goes missing from his home.

An elderly couple are murdered in their Oregon home.

A video tape surfaces after a naval officer is raped and stabbed suggesting the victim may have been silenced to prevent a scandal.

The murder of a Wyoming teenager is investigated.

Investigating a daytime robbery at a nightclub in Arlington, Texas, that resulted in an employee's death.

An elementary school teacher goes missing after her first day at a new job, and investigators sift through clues to uncover the heartbreaking truth behind her sudden disappearance.

When a college student is found murdered in his Arlington, Texas, apartment, investigators suspect the kindhearted victim's generosity may have led a killer to his door.

A young Navy wife is found raped and strangled to death in her home near the Mayport Naval Station in Jacksonville, Fla.

The murder of a popular young woman in Lancaster County, Pa., is investigated.

A friendly night out ends in a shallow grave for a beautiful young woman and her killer evades police for decades.