A V soldier is still on the hunt for Val when her water breaks and her baby will soon be born. Meanwhile, Erica, tired of being on the defensive, decides to go on the offensive and gets herself and Tyler invited up to the Mothership for a get-to-know-everyone-better dinner. But she has more than food on her mind; she's really there to find Anna's soldiers and destroy them. Meanwhile, after Father Jack asks Chad to help get a message to Joshua, he discovers that Anna's been using him.

Erica works with new allies to uncover a biological threat they suspect the Visitors have been plotting. Aboard the mothership, Anna meets with a special guest, while managing the investigation into the murder of a V. Chad does a segment on the V Healing Centers demonstrating their amazing medical abilities, but finds himself conflicted by some of his findings.

Dozens of UFOs suddenly appear on Earth, hovering over major cities around the world and claim that their objective is to help the Human race, providing vastly superior intelligence and technology in exchange for water and minerals only found on Earth. The leader of the Vs, Anna, uses popular TV anchor Chad Decker to deliver her messages to the Humans, but suspicion arises from FBI investigator Erica who believes that the Vs have different intentions to what they claim.

Erica, Ryan and Jack go on a harrowing mission to find the legendary John May in order to rescue Georgie. Anna brings Chad aboard the Mothership for a story on her Live Aboard Program and Tyler confronts his mom about his mysterious past.

Erica, Ryan, Father Jack and Hobbes learn Anna's sent a V shuttle filled with a deadly tracker team to find them, and must figure out how to stop the shuttle from landing. Meanwhile, Anna gives Tyler his invitation to the Live Aboard Program and Chad confronts Father Jack on what he knows about The Fifth Column.

After a violent attack on someone very close to Anna, she delivers a message that the Vs don't feel safe and will be leaving, while she also gives a list of possible Fifth Column members to Chad hoping he'll investigate to help in finding them. Meanwhile, Erica and the team try to track down a scientist who may have created a weapon that the Visitors are afraid of.

Chad reports from the Peace Ambassador Center as 100 diplomatic visas are being issued to the first wave of American Visitors, with Anna getting the first, but not everyone agrees with the decision. Erica has been tasked to protect the Vs and is tracking a death threat while paired with a V officer. Meanwhile, Ryan starts reaching out to his old friends to build up opposition forces and help fight the Vs.

Anna introduces her pilot program to invite select groups of humans to stay on each of the 29 space ships. Ryan must deal with the fact that Valerie's pregnancy is wildly accelerated. Tyler learns a secret about his mom and one of the team makes a sacrifice to save Ryan.

Erica finds her life in danger when she's attacked at home. A dangerous new member is recruited for the Resistance as the Visitors shore up their defenses. Anna wonders why Chad hasn't followed up on his diagnosed aneurysm and Ryan's concern grows over Val's "abnormal" pregnancy.

Chad and Anna are in Geneva for the U.N. Energy Summit where Anna is going to present a gift of technology to the world. Meanwhile, Erica learns that the V Task Force is investigating The Fifth Column. Valerie goes on the run, knowing something is different about her baby and not sure she can trust Ryan.

Erica, Father Jack and Hobbes realize that the Vs know names and addresses of The Fifth Column members and must take drastic measures to protect them, while Ryan finally reveals to Val that he's a Visitor. Chad, with the camera rolling for "Prime Focus", begins the process aboard the Mothership's Medical Bay to have his aneurysm removed.

Chad Decker hosts a debate about the Vs. Suspicion arises from FBI investigator Erica who believes that the Vs have different intentions to what they claim. Erica and Father Jack find themselves being tracked down by a seeker.