The Cooper family grapples with the death of George Cooper Sr.

Sheldon invites the entire school to a party for the Nobel Prize announcements. Also, Connie learns more about Dr. Sturgis' past, and Georgie's desire for cable TV leads to a standoff between him and George Sr.

News of the tornado reaches Sheldon and Mary in Germany. Also, with the Cooper house in chaos, Missy steps up.

Sheldon helps his roommate try to beat the stock market, Missy and Billy Sparks throw a party, and Mary finds a new church.

George Sr. gets an exciting job offer, and Sheldon prepares for his move to California.

Sheldon leaves East Texas for the California Institute of Technology following the death of his father.

A video game takes over Sheldon and Connie’s life. George Sr. is jealous when Georgie bonds with Herschel at the auto shop.

When Dr. Sturgis recommends Sheldon and Missy for a university research study on twins, Mary is unhappy when the test results go to Sheldon's head.

After graduating high school, Sheldon has a breakdown when he realizes he may not be ready for college. Dale tries to make amends with Connie.

Sheldon and Mary head to Germany while the rest of the Cooper family braves a tornado that is heading straight for Medford.

When Mary’s faith is shaken by a tragedy in the community, Sheldon becomes an unlikely ally.

Georgie is thrilled when Veronica stays at the Coopers' house for a few days. Also, Connie and Dr. Sturgis celebrate their one-year anniversary.

The Coopers discuss the possibilities of black holes and alternate universes when Dr. Sturgis comes over for dinner.

Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.

The Coopers can't be found as Mandy goes into labor. Also, Sheldon is excited about the launch of his database.

Sheldon realizes he is the weakest student in his class; Meemaw is looking to expand her gambling business.

Sheldon's published paper leads to a frenzy of grad school recruiting, and Georgie tries to speak more properly in front of his daughter.

Sheldon attempts to build a nuclear reactor. Also, a university cocktail party gets heated when Dr. Sturgis’ colleague, Dr. Linkletter, flirts with Connie, and Georgie is heartbroken when he learns Veronica has a boyfriend.

The gambling room gets broken into and Sheldon wants to study abroad. Also, Missy makes a new friend.

Sheldon explores Germany behind Mary's back, Missy attempts to pull a fast one on George Sr. and Meemaw and Dale adjust to living together.

Sheldon starts an internet flame war, and Missy stands up to the boys on her baseball team. Also, Connie is unhappy when George Sr. spends time with her new boyfriend.

When the IRS accuses Sheldon of making a mistake, he'll stop at nothing to prove them wrong. Also, Dale is forced to get a colonoscopy and tries to convince Connie to join him.

Sheldon is caught in a moral dilemma when offered a bootleg copy of a computer game he can't afford. Also, Mary and Connie take Brenda out for girls' night while George Sr. and the guys watch Billy, and Missy asks Georgie to take her and Marcus on a secret date.

Sheldon makes a terrifying mathematical discovery while tutoring Billy. Also, Mary is jealous of Missy's relationship with Mandy and Connie.

George Sr. is worried that Mary wants another baby and gets a vasectomy behind her back. Meanwhile, Drs. Linkletter and Sturgis go to Sheldon for science tutoring.