Drake has taken advantage of Josh for the last time and Josh decides that he is done dealing with Drake. Drake says he's fine with this, but when Josh's life improves and Drake's goes down the drain this rocker begins crooning a different tune.

Drake, Josh, and Megan must rebuild a tree house that they accidentally destroyed

Josh is confident about when Walter chooses him to be his co-weatherman. That is, until Megan reminds Josh of his uncontrolable twitch. So Josh twitches in front of the whole world and becomes the laughing stock of San Diego. Meanwhile, Drake is determined to win the talent show for the third year in a row but finds it challenging when he rivals with an acappella group.

Drake is getting tired of hanging around with Josh all the time. So Josh finds a friend named Drew who looks just like Drake. Drake feels he is being left out because of Drew, so he finds his own friend named Jerry who looks and acts like Josh.

Drake and Josh make a bet to swear off junk food (Drake) and Video Games (Josh). Megan makes both of them swear to dye their hair pink (whoever loses). When Drake and Josh's mom and dad discover them making a bet, they make a bet as well. When things get crazy, Drake and Josh can't hold onto their bet much longer and decide to break it.

Drake and Josh receive an old dune buggy from a friend but are forbidden to use it. When Drake defies his parents and injures himself after crashing the buggy, he tries to hide his injuries, but gets no support from a grounded Josh.

When Mr. Nichols's boss calls off their dinner plans because of a last minute babysitter cancellation, Josh volunteers his and Drake's services.

Drake finds out Josh is great at pool or billiards as Josh calls it. Drake bets some kids, and takes advantage of Josh's pool skills and starts hustling people, by taking their money, shoes and other clothing/personal items. Now Josh has made the ultimate bet, and Drake's stuffed in the corner pocket.

Drake meets a smart girl from school named Michelle that he really likes. Now, Drake is not the smartest kid in school, so he gets Josh to teach him things to impress Michelle. But things go too far when he accidentally says yes to an offer of joining the Academic Team. Meanwhile, Josh has had enough with Megan's pranks and tries to get back at her.

An obsessed fan is in love with Drake. She loves him so much, she says she's going to marry him and won't leave Drake a moments peace. So Drake must get this #1 fan to stop embarrassing him and ruining his life. Meanwhile, Josh becomes the new chief of the campfire kids but finds it tricky to deal with kids.

Drake & Josh are approached by two salesmen who offer them a one-time deal, Gary Grills. Drake and Josh quickly become attached to them and sell them acceptionally. But they don't realize that these Grills come with a price.

Drake is accused of parking Mrs. Hafer's car in the middle of her classroom. Drake and Josh must go in front of the school's Honor Council to prove Drake is innocent.

It's the time for the Science Fair. Josh is confident that he'll win first prize, until Mindy Crenshaw returns! Josh comes in second like every year, but he turns out to have a change of heart. After the Science Fair, he develops a liking of Mindy who also has a liking of him. Right before they know it, they're boyfriend and girlfriend!

Drake's "friend" Tori, who he has been dating for a while, calls him her boyfriend. Drake breaks up with her, because he thinks they both should see new people. Meanwhile, Josh grows a mustache and is determined to make Mindy kiss him again.

Mindy invites Josh over to her house for dinner and to meet her parents, but things don't go well. Josh hosts another dinner at his house to try and impress Mindy's parents to make up for last time. He asks Drake to not mess up his date. Meanwhile Drake and his new girlfriend, Lucy, wrestle to see who is tougher, to prove that some girls are tougher than boys.

Megan buys a pregnant sheep and makes Drake and Josh take care of it, if Megan Promises to not pull any pranks on Drake and Josh for awhile. But when they see what a pregnant sheep can do, they don't want it much anymore.

Drake and Josh decide to turn the tables and prank little Megan. She actually believes that aliens are coming down to Earth and they are going to kidnap her. But at the end, Drake and Josh find that this may not go as they hoped.

Drake and Josh go on the Dr. Phyliss Show and relive some of their most outlandish moments. Some will jab at your funny bone, while others will tug on your heart strings.

Josh is jazzed at the prospect of meeting his TV idol when Drake gets tickets to “Oprah” for his birthday, but delight turns to dismay in the studio parking lot.

Mrs. Hayfer needs a house sitter for the weekend and it's the boys to the rescue, but all doesn't go according to plan when they meet Tiberius, a vicious dog with an appetite for… Drake and Josh?! Walter is exercising for the mile run against another weather man.

Drake teases Josh that he can't get girls. So, Drake and Josh make a bet to see how many girls each of them can date in just one week. The rules are, every date must last at least one hour, you can't date someone you already know, and you can't date the same person twice.

Drake and Josh enter a "Pump My Room" contest to try and redecorate the living room as an anniversary gift for their parents. When they come back to the house they realize that everything is gone. To get the furniture and everything else back, Drake and Josh get a job at a sushi factory, but come home to see that everything is back.

The most popular kid in school is throwing what may be the greatest sixteenth party ever, but Drake and Josh may be having cake for two after they get banned from the party.

It's the end of an era. After Josh ruins Drake's chances at having a hit song in the Superbowl, the boys must find a way to make things right.

Drake wins a free skydive off a helicopter and sets off to do it despite his parents' wishes. Josh, being the good brother he is, tries to stop him, but ends up going along for the ride. This fun time in the sky becomes a true downer when they accidentally lose their pilot and things start spinning out of control.