Friends and comedians Jay Larson and Sean Patton explore bars featured in Esquire magazine’s annual rundown of the best in the country with stops in Milwaukee, Chicago and San Francisco.

Jay and Sean visit Portland, Oregon, a town known for its alternative ethos and hipster spirit. From a microbrewery and a small batch whiskey bar to a rum club and a spot for an authentic Spanish coffee, the guys take in the city’s artisanal culture, jump on an old-timey bar bus tour, and check out the town’s oldest strip club. Special guest: The Decemberists’ Chris Funk.

Jay and Sean visit Austin, Texas, a town that embraces the craft cocktail movement while giving it a unique local twist and a dash of downhome Texas charm.

Jay and Sean visit New York City, where they meet the creator of Esquire magazine's annual best bars list and follow his advice to find the best watering holes in the Big Apple.

Jay and Sean visit Jay's hometown of Boston, and create a whirlwind tour of Beantown.

Jay and Sean search for the best hotel bars in the U.S. Comedians Nick Thune and Jen Kirkman appear.

Jay and Sean travel the country looking for that which is often overlooked, the best hotel bars in the country. Special guests include comedians Nick Thune and Jen Kirkman.

More than just sleazy neighborhood dumps, Jay and Sean hunt for the best dive bars America has to offer.

Jay and Sean visit New Orleans, Louisiana, the birthplace of both jazz and Sean Patton.

Jay and Sean end their cross-country journey back home in Los Angeles; guests include comic Rory Scovel, chef Roy Choi and musician Matt Sorum.