It’s April 1970. Rising rates of gonorrhoea in the district cause alarm, and Trixie cares for an unmarried first-time mother recently diagnosed with a mental health condition.

Sister Julienne is drawn into the heart of a different culture when she is called upon to help a Pakistani family. Having come to terms with her own childlessness, Mumtaz Gani is heartbroken when her husband Saddiq brings home a second wife who is eight months pregnant. Sister Julienne must help Mumtaz come to terms with this new addition to her family.

A fun day at the seaside proves traumatic for the Turners and puts May’s future with them in jeopardy. Nurse Crane helps a young couple cope with a rare cancer diagnosis.

The Sisters welcome new postulant, Sister Catherine, to Nonnatus House, whilst a bold intervention boosts numbers for the measles vaccination clinic.

The midwives help a family with a history of drug addiction. Dr Turner and Shelagh take the final steps in May’s adoption, whilst Joyce faces the disciplinary board.

Jenny Lee start her midwife career at Nonnatus House in London. She is surprised to find that it is a nursing convent and not a hospital. Her first case is a woman pregnant for the 25th time!

Sister Monica Joan seeks advice from a clairvoyant. Matthew is shocked to discover squatters in one of his warehouses, and Shelagh faces the most challenging delivery of her career.

April 1968. Racial tensions cast a shadow over Poplar, Nancy’s eyes are opened when she supports a dying woman, and Nonnatus House welcomes a new sister.

Sister Veronica is shaken when a mother reveals a terrible truth about her marriage, whilst Shelagh cares for a baby with a life-threatening condition and Nancy harbours a secret.

In his new role, Cyril faces his toughest challenge yet, whilst Matthew is summoned to a board meeting with his mother. Elsewhere, the pupil midwives prepare for their final exams.

It's March 1970. The team support a pregnant teenage girl whose parents believe in an immaculate conception. Demonstrations cause havoc for the Nonnatus team, whilst Nancy’s relationship blossoms.

Joyce faces a difficult situation when a mother suffers postnatal complications, a council strike leads to an outbreak of Weil’s disease, and Cyril’s life is turned upside down.

An expectant mother with financial struggles enters into a painful arrangement with her cousin. As Tom provides pastoral care, he reveals why this case touched him more than most.

Lucille must win the trust of a mother who is terrified of giving birth. Nurse Crane and Dr Turner are anxious to find a possible smallpox sufferer.

Sister Julienne volunteers to put up four trainee doctors at Nonnatus House while they undertake the practical aspect of their obstetrics diploma, hoping the exercise will remind the council how vital the home is to the community and help remove the threat of demolition.

Sister Hilda and Dr Turner are involved with a young woman whose health presents a series of challenges. A complicated pregnancy leads the Nonnatus team on a path of discovery.

At the monthly cytology clinic, Sister Frances comforts a young woman who is struggling with a life-changing diagnosis. Lucille supports a difficult mother.

Sister Julienne helps care for a first-time mother who is going through a challenging diagnosis. Lucille struggles with her own health, and Poplar celebrates the Whitsun Maypole.

A pregnant mother with a chronic heart condition falls unwell, Nancy grows suspicious of a young father’s erratic behaviour, and Matthew prepares for a visit from his father.

Poplar’s housing crisis deepens, bringing a sad case to the attention of the team, whilst a worrying disease outbreak directly impacts the residents of Nonnatus House.

The team help a single mother whose flat is riddled with damp whilst Nancy and Dr Turner care for a Sylheti woman with an undiagnosed illness, and Matthew teaches Trixie how to drive.

Rosalind requires all her skills as a midwife when a disabled baby is delivered at the maternity home, whilst a gas explosion in an old tenement building shocks the community.

November, 1970. The challenges of midwifery hit close to home when a mother and baby home is evacuated. Nancy’s wedding plans take a surprising turn, and Sister Catherine takes her first vows.

Chummy makes an important decision, Jenny reconnects with Jimmy, and Cynthia's conduct is called into question after the death of a baby she delivered.

The team reunite but all is not well when a change of management shakes up Nonnatus House.