With both patients and the whole Healthcare system on the brink of tragic events, the St Mary's nursing team must put their own struggles aside to help those with everything on the line.

With uncertainty in their personal lives and a pandemic on the horizon, our nurses each deal with people longing for wishes to come true for their health or their loved ones, but they're wishes that may not be in the power of a nurse to grant.

When a tragic accident at a concert suddenly puts St Mary's in a Code Orange, our nurses will realise how important it is to have someone in your corner, because no one should be alone.

It's Nursing Week and St Mary's nurses and patients alike are confronted by the fact that everyone has a hidden side, and that nothing can be taken at face value.

Assigned to the Burn Unit, Naz and Grace are pushed to their limits as Nurses - and friends - when they disagree over how to deal with a critically burned patient who's in danger of losing his will to live.

A hospital is a battlefield, as our 5 favorite nurses attack another season. But there's a new general in town - nurse manager Kate Faulkner, who's going to give them all a run for their money.

An Amber Alert rings out at St. Mary's, but unbeknownst to the nurses the perpetrator and the abducted child are in the hospital.

Hospitals are no stranger to the things that keep us up at night or the secrets we keep, as the strange gets stranger on the night shift at St Mary's.

Ghosts from the past make a day at St Mary's especially trying for our nurses as they're each confronted by people or things they tried to leave behind.

A high-profile surgical case brings Grace and Ashley into conflict over whether or not the surgeon is capable of performing the surgery.

Ashley and Caro explore past relationships. Keon grapples with Molly's attempts to sideline him. Naz tries to balance her emotional connection to a patient with his medical needs. Wolf is forced to leave his comfort zone and care for a newborn baby.

Grace mediates between a patient's partner and son while adjusting to the unwanted arrival of the new hospital CEO.

When Naz realizes her patient has a more serious condition than anyone realized, Naz forms a special bond with the patient's cousin. An over-exhausted and under-slept Wolf struggles on the job and draws Damien's wrath.

Keon finds himself supporting his patient's fiancée when a swift recovery has an unexpected side effect. Naz treats a former Olympian whose rare condition requires creative solutions. Wolf helps a frequent flyer with hearing loss.

Keon gets hazed by Nurse Molly, then gets off on the wrong foot with a patient in handcuffs. Wolf suddenly finds himself under serious financial pressure and considers taking desperate measures.

Under pressure to steal more drugs, Wolf is forced into an ethical dilemma in which he is turned against his patient. While trying to protect her patient before a major surgery, Ash is forced to confront Sinead about her drinking problems.

Grace to is forced to confront her own past trauma when she encounters a patient whose diagnosis proves to be elusive.

Wolf is assigned to a patient that has lost hope that she will receive a life-saving lung transplant in time. Keon confides in a former football friend about a traumatic incident. Naz is assigned as Sinead's assistant.

Ashley receives an ultra-religious patient who is willing to put himself at peril to appease God, forcing Ashley to reconsider her own religious past. Naz supports a pregnant patient through the hardest decision of her life.

Keon assists a patient who goes into early labour. Naz cares for a victim of the terrorist van attack and helps his mother make a difficult decision. Meanwhile, Wolf tries to reunite missing fingers with their owner.