Zoe's first day as the ED'S clinical lead gets off to a trying start when the team are faced with dealing with the aftermath of a tunnel collapse at a music festival.

Tamsin faces a ghost from her past when she and Jeff attend a call out at a lap dancing club. Sam attempts to unravel the mystery of a patient with amnesia.

Sam and Tom are pushed to their limits when a female cage fighter insists on fighting against their advice, and a wedding is threatened to be ruined by devastating news.

Dylan and Tess must treat an agitated pregnant woman, while Fletch tries to unravel the relationship between a teenage girl and her swimming coach.

The team is put to the test when Holby is hit by severe weather, and the stress of work and dealing with a face from the past leads Big Mac's health to take a dangerous turn.

Medical drama. Fletch plays a practical joke on Lloyd after a staff night out, and Dylan attempts to teach a medical student about the dangers of alcohol abuse.

The team deal with an accident at a troubled small business, and a young businessman with heart problems is demanding staff find his missing phone

Zoe oversteps the line when she attempts to help a vulnerable young woman, and Mac gets into serious trouble on his first day back when a patient with Alzheimer's appears to have swallowed some cleaning fluid.

Zoe struggles to deal with the fallout of a suspected E. coli outbreak, and Dylan is touched by an elderly patient who has lost his beloved wife.

Zoe and the ED reap the fallout from the E-coli outbreak and things go from bad to worse for farmer Rob.

Dylan deals with a woman whose pregnancy is not all it seems, and teenager Angel is desperate to get some cash together to pay off her bullies.

Tamzin's decision not to treat an aggressive patient has serious repercussions, and Tom and Sam differ over how to approach a family with a dark secret.

A family are shocked to find out an intruder isn't all he seems to be, and a woman finds out she's the heir to her nasty aunt's fortune.

As Charlie and Big Mac prepare for the ED party, Dylan's suspicions reach boiling point.

A secret puts a strain on Jeff and Tamzin's friendship and makes life difficult for Dixie.

Tensions once again rise between Tom and Dominic as they argue over the treatment of a baby with severe hypothermia, and Dylan finally admits that he has not moved on from Sam.

Four student nurses receive a baptism of fire on their first shift in the ED.

Zoe is concerned that Jordan is not facing up to the severity of Yvonne's condition.

Jordan fights to keep his girlfriend's life support machine switched on but when an ill young woman arrives in the ED, he's forced to reconsider his motives.

It is the day of Yvonne Rippon's funeral, and Nylon gets Jordan to visit him.

Jordan is called on to save the life of the person who killed his girlfriend.

New doctor Ash hits the ground running when he treats a patient with suspected rabies, and Aoife is forced to take control when ex-boyfriend Craig arrives in Holby.

David tracks down his estranged wife, Kate, to get her help in saving their 10-year-old son who is dying of leukaemia. Meanwhile, Zoe has had to go home sick, leaving Ash to deal with the continuing flu epidemic.

Jeff must persuade David to act in his son's best interests, Fletch is determined to help an elderly man in love, and Zoe returns from sick leave and clashes with Ash.

Big Mac thinks he may have finally found the woman of his dreams but when she mistakes him for a doctor he doesn't set her straight. Ash clashes with Zoe when he carries out a risky procedure without telling her.