Leonard Nimoy plays a heart surgeon whose talents turn to murder. Stung by jealousy, he's planning a surgical death for his brilliant but ailing associate. Will Geer plays the intended victim.

A police commissioner provides an alibi to a friend who has just killed his wife. Later the commissioner kills his own wife and gets the friend to repay the favour.

A wine connoisseur kills his half- brother to prevent him selling the family winery to a merchant company so he can pay off his gambling debts.

A writer of murder mysteries wreaks revenge on her nephew-in-law by blaming him for her niece's murder.

An architect kills his business partner and deliberately lets Columbo suspect him, leading Columbo to think that he's hidden the body in the foundation of a building under construction. He plans to let Columbo dig up the site and find nothing, knowing that its the perfect place to hide the body since Columbo would never look in the same place twice.

A Senate Candidate running for office kills his campaign manager by making it look like he was the target for the killer's bullet.

Brilliant photographer Paul Galesko plans to murder his domineering wife, Frances, and pin the crime on an ex-convict named Alvin Deschler. His plan is to make it look as if Alvin kidnapped his wife and killed her before picking up the ransom money.

Columbo matches wits with a brilliant attorney responsible for the murder of the one man who could stifle his meteoric political career.

The mistress of a conductor becomes a target for murder after threatening to tell all to her lover's wife.

A wealthy man is murdered; his twin nephews stand to inherit, but which one committed the crime?

A filmmaker kills one of his clients. in a break, during the screening of a new ad campaign

A Country and Western singer kills his overpowering wife in a plane crash while he parachutes to safety.

While holidaying on board a cruise liner, Columbo helps capture the killer of the singer with the ship's band.

A fading actress kills her husband when he refuses to back her comeback show.

Nick Franco is a violent, two-timing gigolo and his current paramour, Laura Stanton, has had enough. With the help of a young woman named Lisa, she murders her lover and sets herself up with an airtight alibi. When Columbo starts sniffing on her trail, Laura quickly works to seduce the married detective, hoping that her sex appeal will throw the usually stubborn Lieutenant off the scent.

One member of a mystery-writing-team decides to kill his more talented partner when the better writer decides to go solo.

The head of a military school kills one of the governors by sabotaging the gun which is used on founders day.

An inventor video tapes his mother-in-law's death, and then replays it back to the security guard, to give himself an alibi.

Two former college friends, now partners in an accounting firm, become enemies when one realizes the other has embezzled funds. The reason for his embezzling ways is his wife, she demands nothing but the best.

An art critic, Dale Kingston, kills his uncle for his valuable collection of paintings. All the clues lead to the dead man's first wife. Can Columbo correct the Lieutenant's error before it is too late?

The manager of a football team kills the team's owner, disguising himself as an ice cream vendor as a cover. He then uses a recording of a faked phone call as an alibi to prove he was elsewhere at the time of the murder.

Master magician the great Santini is amazing audiences at the Cabaret of Magic. What they don’t know is that Santini hopes to pull of the grandest illusion of his career - making club owner Jesse T. Jerome disappear. The crude Jerome is the only person who knows that Santini was a Nazi death camp guard named Stefan Mueller, He has been blackmailing the magician since learning his dark secret.

A famous psychiatrist uses an appointment with his doctor as his alibi while he calls his house, where his dead wife's lover is. The call serves as the first step in a conditioning reflex on the psychiatrist's dogs. The other part is the word Rosebud as uttered by the victim. When Columbo arrives on the scene, the psychiatrist is very understanding when police say they may have to put his dogs to death. But Columbo notices how friendly the dogs seem, and then there's the telephone that's hanging from it's hook.

After winning a $30 million lottery, photographer Freddy Brower, who wishes to keep the money a secret from the wife who is divorcing him, arranges with his uncle, wealthy jeweler Leon Lamarr, to pretend the lottery ticket is Lamarr's, until the divorce is final. Little does Brower know his uncle is having an affair with Brower's wife. Lamarr kills Brower in order to keep the lottery winnings for himself.

A chess grandmaster disposes of the champion, who keeps coming back on him.