Leonard Nimoy plays a heart surgeon whose talents turn to murder. Stung by jealousy, he's planning a surgical death for his brilliant but ailing associate. Will Geer plays the intended victim.

A wealthy man is murdered; his twin nephews stand to inherit, but which one committed the crime?

The mistress of a conductor becomes a target for murder after threatening to tell all to her lover's wife.

A fading movie star tries to murder a writer who is attempting to blackmail her, but accidentally kills her P.A.

The manager of a football team kills the team's owner, disguising himself as an ice cream vendor as a cover. He then uses a recording of a faked phone call as an alibi to prove he was elsewhere at the time of the murder.

A chess grandmaster disposes of the champion, who keeps coming back on him.

Jarvis Goodland, along with his nephew, plan a kidnap scam to break the nephews trust fund, but after the money has been collected, Jarvis kills his partner.

While on a work trip to London, to learn the techniques of the British police, Columbo gets involved with the murder of Roger Haversham, a rich old businessman who is financing the careers of two rundown theater stars. When Sir Roger threatens to end their careers, because he felt betrayed, he's killed. A short while after, his butler figures out the motives for his master's murder, and blackmails the actors, who have no other choice than to kill him and make it look like he commited suicide due to remorse, because he murdered his employer. Columbo stills manages to catch both the murderers, with the help of a pearl and a new umbrella.