The family and friends of brilliant naval architect Commodore Otis Swanson have gathered for the company’s annual party. The commodore, however, has become increasingly discontented with the way his son-in-law, Charles Clay, has developed the shipbuilding firm into a vast, impersonal corporation. He is tired of being surrounded by freeloaders like his alcoholic daughter, Joanna, his irresponsible nephew, Swanny, and of course, Charles. The only man he respects is Wayne Taylor, the head of the boatyard. In fact, the Commodore intends to sell the company. That night, Charles is wiping clean the belaying pin used to bash the Commodore’s skull.

Columbo attends the wedding of his police officer nephew. While her husband takes a shower, the bride disappears from the bridal suite. The groom enlists Uncle Columbo's help in unraveling the case. Seems she has been kidnapped by a psychopath who intends to kill her once he consummates "their" marriage.

A photograph is the only clue for Columbo when two dead men and a seven year old mystery with $4 million dollars involved as well as an obnoxious insurance investigator come into play.

The owner of a bull ranch in Mexico gives his workers the day off, and then talks his number one man into fighting the bull who nearly killed his son. But instead he shoots him with a tranquilizer gun, and lets the bull kill him. Colombo, who is on vacation in Mexico, gets dragged into this case by an admiring colleague, but he has trouble convincing the Mexicans that the accident is really homicide. And how do you prove that the bull is a murder weapon?

An ambitious womanizer, rejected by the romance novelist he planned to marry, ends the story she was writing with a gun and makes the murder look like robbery gone awry.

Graham McVeigh, a thoroughbred ranch owner, kills his brother, and frames a local mob bookie. Then, under the guise of making good on his brother's debt, he kills the bookie as well, claiming self-defense. Mob boss Vincenzo Fortelli starts to exert pressure on McVeigh. To solve the crime Columbo must work with the gangster.

Mortician to the stars Eric Prince, kills gossip reporter Verity Chandler, who had knowledge of skeletons in Prince's closet. Columbo must figure out what happened to her and why.

Hollywood film composer and conductor Findlay Crawford has been mentor to a talented young composer who has been ghostwriting most of Crawford's work for the last few years, and penned Crawford's entire last movie score, which won an Oscar. When the protege wants to venture out on his own, Crawford, whose own talent seems to have run dry, concocts the perfect murder, made to look like a suicide.

A famous general kills a business associate, then woos a neurotic female witness to thwart Columbo's investigation.

Frank Brailie runs a private military foundation for wanabe soldiers owned by the wheelchair bound General Padget. The General has become suspicious of Frank as a great deal of money seems to be going to a Special Projects Fund. The General tells a close colleague to investigate Frank and the Special Projects Fund. Instead of reporting his fraudulent findings back to the General, he decides to blackmail Frank for some of the money, Frank agrees and starts to plan his murder.

Cathleen Calvert and her lover, crime scene investigator Patrick Kinsley, plot to get rid of Calvert's husband, Clifford, a powerful businessman, by killing an investment broker with whom he is currently feuding, and pinning the murder on Clifford. As long as he is alive and in prison, Cathleen has access to all his money. Columbo must uncover a criminal who is part of the team handling the investigation.

While on a work trip to London, to learn the techniques of the British police, Columbo gets involved with the murder of Roger Haversham, a rich old businessman who is financing the careers of two rundown theater stars. When Sir Roger threatens to end their careers, because he felt betrayed, he's killed. A short while after, his butler figures out the motives for his master's murder, and blackmails the actors, who have no other choice than to kill him and make it look like he commited suicide due to remorse, because he murdered his employer. Columbo stills manages to catch both the murderers, with the help of a pearl and a new umbrella.

The director of a government institute that employs various scientific geniuses commits a clever murder. But another kind of genius is on the case: Lt. Columbo.

Lt. Columbo is invited as guest speaker in a Criminology course and squares off against two cunning students, who are confident they have duped the lieutenant with various leads, when their professor is found murdered.

A chemist rigs a bomb in his uncle's car to gain control of his uncle's company, then plants clues to make Columbo suspicious of the company's Vice-President.

The female head of a museum hires one of the guards to rob the museum to collect the insurance money. But during the robbery she kills him and her own brother, and makes it look like they killed each other. The guard/robber's brother reports a strange message on his answering machine, that makes it seem that he has been killed. And Columbo gets the case. When Columbo first comes to the crime scene, he notices that the lights are off, a gold medallion in the robber's pants, and signs that pointed to the fact that he was going abroad after the heist. And he concluded that these clues mean that someone else was involved.

The final Columbo story starring Peter Falk, Los Angeles rave promoter Justin Price helps his girlfriend Vanessa get rid of the corpse of her ex-husband, who was backing Price's new club, after he drops dead in Vanessa's apartment. When an investigative reporter pieces the crime together and threatens to blackmail Justin, Justin kills him.

A woman shoots her overbearing brother, claiming she thought he was a burglar. Columbo doesn't buy the self-defense claim - he know's it's murder.

Viveca Scott, the founder of Beauty Mark Cosmetics, is being threatened by her rival David Lang. When he finds out that her revolutionary cream formula actually removes wrinkles, he has the formula pirated.

An ambassador from Suari and his code clerk kill the chief of security in an attempt to make it look like the chief was a traitor, who blew up the legation safe and stole £600.000 on behalf of a dissident group. But Columbo gets suspicious. He just has one problem crushing the ambassador's alibi and then, when the code clerk turns up dead, the ambassador has an alibi again. But even if Colombo could rock the two alibis, there is always the immunity problem.

Lt. Columbo delves into the world of magic, ESP and slight of hand as he investigates the death of a magician, and there appears to be a tie to a prodigal psychic supported by a government founded institute on parapsychology.

A sex therapist catches her boyfriend with another woman when he thinks she is out of town. She then disguises herself and manages to kill him while in disguise, not realizing that a potential suitor saw her enter the bathroom as a dark-haired woman and exit as a blonde.

A famous artist, Max Barsini, lives with his wife Vanessa and a beautiful live-in model named Julie at his beach house/studio. Max's ex-wife Louise lives in the beach house next door. Together, these women comprise Max's own little harem. He loves them all in different ways, but, more importantly, likes to control them. In fact, Max derives a great deal of satisfaction from the fact that they all fight for his attention and are reliant upon him financially and emotionally. The competitive jealousy between the women reaches a head at the dinner table one night when Max asks each of them what they think of the other. Their answers prove the intense rivalry between the women.

While investigating the death of a popular actor, Columbo must outwit a cunning dentist, who has set up his wife for a murder in order to keep up his image and expensive lifestyle.

Wade Anders, a former security expert, hosts the show Crime Alert. A rival host, news reader Bud, discovers Wade was in a porno movie and plans to tell the world then take over his show.