The most exclusive jewelry auction of the year ends abruptly when an appraiser is killed during the event. The investigation takes an emotional turn when the CSIs must confront one of the greatest tragedies in human history - the Holocaust.

In the one hundredth episode of CSI: NY Mac faces his most deadly foe yet. There is a serial killer loose in New York City killing people with the name Mac Taylor making Mac a target.

A woman is found in the trunk of a crushed car at an auto wrecking yard, the autopsy reveals that she was pregnant, the team needs to find out who she is so they can find the baby.

A lethal pipe-bomb blows a Manhattan townhouse and valuable evidence to pieces, forcing the CSIs to get creative in reconstructing the damaged clues that ultimately lead to the bomber.

When a supposed air marshal is murdered on a flight to the District of Columbia, Mac searches the plane for the killer and the murder weapon.

The team investigates the puzzling death of a woman named Ann Steele. To solve the case, the team must look for a life size silicone doll. When the team runs into the factory that makes them, it prompts some amusement for some of the team. Meanwhile, Hawkes meets up with an old college friend who later asks him to compromise some evidence in the case.

Three drug dealers set to stand trial are found dead in separate places. They were all trying to get rid of witnesses in their crime, but it looks like someone got them first.

The team investigates the brutal murder of a house relocator who was found dead inside a Victorian house that he was about to move from Staten Island to The Upper East Side.

The team is forced to investigate two crimes at once when a mysterious energy field seems to be the cause of a billionaire's disappearance and the death of his limo driver.

Mac runs into Ella McBride who could cost him time in figuring out if Isabelle Vaughn died by eating the miracle fruit. Stella gets in trouble with Mac while investigating another murder linked to the Greek diplomat that attacked her.

Young brides-to-be fight over a killer dress at the biggest wedding gown sale of the year and one of the shoppers winds up dead. The unusual clues of this case force Dr. Hawkes to confront a painful chapter from his past.

A Russian tourist is found stabbed to death and the CSIs come face to face with the frightening realities of human trafficking. Solving this case becomes personal when it directly affects a prominent member of the NYPD

When a young woman appears to be strangled while participating in a live online chat that Adam witnesses, the CSIs must determine if it was real or a hoax, and locate where the possible victim is.

On the 10th anniversary of 9/11, Mac and the team remember specific moments from that day that were indelibly burned in their mind.

When Mac is shot, he finds himself in limbo between life and death and, as he fights for his life, it's up to his team to bring the shooter to justice.

After Flack makes an enormous drug bust, and locks it up at CSI, the drug lords infiltrate the building at gunpoint to get them back. Now the team must resolve the hostage situations, all the while with Mac, Stella, and Hawkes trapped inside.

Mac informs an ex-con that he served time for a crime he didn't commit, and Lindsay tells Danny "it's time" for the first CSI baby to be born.

When Stella discovers that New Yorkers are being murdered over ancient Greek artifacts, she hands over her badge to follow a clue that leads to Greece and, together with Mac, she uncovers one of the greatest mysteries in history.

When the body of a beautiful young woman is found in a stolen Ferrari, the investigation leads to a family of car thieves, but the CSIs must find the murderer before the rest of the family meets the same fate.

The CSIs investigate when a role-playing game turns lethal, with one player falling victim to a bona fide killer and the other kidnapped and held for ransom.

When the CSIs investigate two seemingly unrelated deaths, their separate trails of evidence lead to a surprisingly connected conclusion.

When a lab tech is murdered in a case that has eerie similarities to a 1950's cold case, the CSIs get a glimpse into what goes on in the shadows of the lab.

Picking up where the season 4 finale left off. The team is investigating the death of a woman named Lauren Santana whom is linked to the bank robbery. She is a friend of Flack's sister Samantha. Also Mac has escaped the robber but the bodies are still piling up. So the team must quickly find the bank robber before he is able to get away.

A frantic 911 call sends the CSIs into a vacant penthouse; however, instead of finding the caller, they unearth a nearly 100-year-old corpse and find themselves navigating their way through a booby-trapped house.

The CSI team investigates the shooting death of an archaeologist whose secret life may have caught up to him.