The body of a man is discovered on the Brooklyn Bridge, and the only evidence is a huge marriage proposal in lights. The CSI team works through the investigation as they learn to deal with a new medical examiner.

A reformed drug addict with everything to live for is found dead in an alley. The CSI's discover he was the victim of a premeditated plot.

The CSI's handle to puzzling cases; Carensa is a young Suicide Girl who at 17, wanted a change of scenery and to become a Suicide girl, at 18 she gets her wish only to lose her life. Chopper, a rising street basketball star, a homeless man trying to change his life for the better is killed and leaves a painful trail of blood which leaves Mac to figure out where and how he died.

Mac and Stella work on the case of a female roller derby player. Danny and Hawkes look into the murder of one of New York's upcoming crop of writers.

Danny is on his way home after a long shift and finds Randy Williams subway surfing. Mac and Lindsay arrive on the scene and begin to wonder if Randy Williams died from riding on top of the subway. His death is even more suspicious after they examine the body more closely.

A death row inmate's final request brings Dr. Hawkes to a Pennsylvania prison and face-to-face with a tragic incident that he has kept secret for many years, just as a prison riot erupts and traps Hawkes inside.

Junkie Jordy Thompkins was shot dead in an alleyway, but the bullet that killed him is missing. Taylor and Hawkes soon realise that a rat may have eaten the bullet, and finding the rat leads them to a robbery that occurred earlier that day. After Robin Prescott is found raped and beaten in Central Park with only a peony leaf on her clothing, Stella and Flack have the daunting task of trying to find the man who raped her, but Prescott has no memory of the crime.

Is it possible to solve a murder 24 hours before it happens? Mac wonders if the suspect traveled through time to know about the murder in advance.

When the chief investigator of a controversial report documenting corruption within the NYPD is gunned down the day before his findings are published, Mac and Stella must find the killer, launching a massive search that makes every officer listed in the report a suspect. Meanwhile, Danny and Aiden investigate the murder of a gypsy cab driver.

Two women both claim to be the wife of a murder victim surprise Mac and Stella at the circumstances of their relationships. Both women have been in a trinogamous marriage with the victim. Meanwhile, Danny and Lindsay investigate the murder of a young woman who is found off a dock tangled up in kelp while she is dressed as a mermaid.

Can knowing a secret be a motive for murder? The CSI team must figure out if a change in gender is cause for the death of a showgirl. Also Lindsay goes back to Montana to try to put the person who committed the murder of four friends behind bars.

The team finds three young women, all of whom appear to have been brutalized in the same way. The only witness they have is the surviving young woman, who can communicate only through blinking. Photographs found at one of the crime scenes lead the team to a couple that had sponsored one of the victims, and the boyfriend who claims he hasn't spoken to her in weeks.

Danny and Mac investigate after a briefcase belonging to Luke Sutton is found left in the NYMEX with a bloody note inside. Their investigation into Sutton's activities lead them to Nick Lawson, whom Sutton had been investigating for illegal trades, but who swears he had nothing to do with his disappearance. Stella and Flack investigate the death of Trina Rolston, a young pregnant women who fell to her death from the roof of a church. With Hawkes help, Stella realises that the body was thrown off the roof to mask the true cause of death. The detectives soon realise that their two cases are connected.

Mac and Stella investigate the murder of a woman who was stabbed in the heart with a wooden stake. The police arrest a woman who was kneeling over the body with blood on her, but Mac isn't convinced that she committed the crime.

The detectives investigate a murder at a grocery store that is also connected to the death of a young man with the tattoo "Tanglewood" on his back. A third case involves a woman who was killed in a hit-and-run auto accident.

Mac and Lindsay question Kid Rock because he was the last person to see his limo driver alive when the driver is found dead in the alley just before Kid Rock’s encore performance concert.

The team is led to a crime scene in the middle of the city involving a parachute jumper whose parachute apparently failed. And one CSI is injured when a snake is found at a crime scene.

Trouble begins for Mac when Clay Dobson becomes a free man due to a mistake he made. Stella learns the results of her HIV test from Adam.

The life of a transplant patient hangs in the balance as the team tries to find the hijacked plane carrying the liver.

Mac receives a phone call confessing to an old murder before the caller commits suicide. The call leads the team to a football stadium to uncover a body and they learn the suicide victim belongs to the Tanglewood gang. They also find a cigarette that puts Danny's job on the line after his DNA is found on it. Stella and Danny investigate the death of a businessman who used the services of an expensive call girl service.

The team find themselves investigating something that isn't usually on the Statue of Liberty. Can a musician's life be saved before time runs out?

After a skeleton is found on a tour bus and turns out to be over a decade old, Mac and the team use the backpack they have found to track the belongings to a young man named Aaron Moreland, only to learn that the body they have cannot possibly belong to him. By tracing the victim's shirt, detectives are led to a youth center worker who claims not to remember the boy, but is hiding an old secret of his own.

A young woman dies after she starts bleeding from the eyes, nose, and mouth while at a party aboard a subway train. Mac originally believes she is the victim of a biological attack. Later, it is revealed that Sheldon knew the victim. Across town, a wealthy playboy is found dead in an indoor lap pool in his penthouse suite. The investigation reveals that he was murdered and his last maid was fired two days earlier.

When a buzzard flying over Manhattan drops a human eyeball from its claw, the race is on to find the body it belongs to before the avian saboteur flies away with the rest of the evidence.

Mac is on the hunt for a sniper who is using nitroglycerin in his bullets to explode on impact, and the prime suspect was once a missing boy from one of Mac's old cases.