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Will Ferrell and Seth Rogen star in this episode about how teenage writer Mary Shelley created her legendary novel, “Frankenstein.”

Deborah Sampson goes undercover as a man to fight in the Revolutionary War, Rose Valland rescues art from the Nazis, and Clara Barton becomes "the angel of the battlefield."

British suffragettes learn jiu-jitsu, Gwendolyn Sanders ignites the Birmingham Crusade, and Judy Heumann leads a sit-in for people with disabilities.

Frances Cleveland uses her public image for good, Edith Wilson acts as president after her husband has a stroke, and Dolley Madison saves American artifacts from destruction.

Alexander Graham Bell beats Elisha Gray to the patent office for the telephone, Thomas Edison endeavors to launch a filmmaking monopoly.

Mystery writer Agatha Christie vanishes, a man known as D.B. Cooper successfully hijacks a plane, and a series of anonymous letters haunts the town of Circleville, OH.

The U.S. reluctantly accepts the Statue of Liberty, Sybil Ludington goes on an epic ride to warn of a British attack, and journalist Nellie Bly infiltrates a corrupt mental institution. Featuring Laura Dern, Taran Killam, Juno Temple and Matt Walsh.

Fred Rogers fights for public television in front of Congress, journalist Ida Tarbell takes on John D. Rockefeller, and Maya Lin designs the Vietnam Veterans Memorial.

An Italian handyman steals the “Mona Lisa,” the “Santa bandits” rob a bank in Texas, and Mossad agents capture a Nazi general who had escaped to Argentina.

Mary Mallon spreads typhoid fever wherever she goes, and Cleopatra’s younger sister Arsinoe schemes her way in and out of power in Ancient Egypt.

The Kellogg brothers litigate over their famous surname (and the newly profitable discovery of corn flakes), Ralph Nader goes to war with General Motors and Harry Houdini and Sir Arthur Conan Doyle go from best friends to bitter rivals.

Scientist Percy Julian overcomes racial barriers, Claudette Colvin refuses to give up her bus seat months before Rosa Parks's famous protest, and Joe Louis fights German boxer Max Schmeling. Featuring Jordan Peele, Terry Crews and "Weird Al" Yankovic.

Pirate Jean Laffite helps Andrew Jackson defeat the British during the War of 1812, Sam Zemurray becomes a banana kingpin and Louis Armstrong becomes a jazz legend.

Nellie Bly and Elizabeth Bisland race each other around the world, New York's newsboys go on strike, and a political cartoonist exposes a corrupt politician.

Occultist and rocket scientist Jack Parsons works on his "sex magick," W.C. Minor helps write the Oxford English Dictionary, and Rasputin lives the high life in Russia.

John Pemberton invents Coca-Cola (from wine and cocaine!), the F.B.I tries to take down Martin Luther King Jr. and Stetson Kennedy infiltrates the Klu Klux Klan.

Dolly Parton has to leave the man who made her famous, competing lawyers clash in the Scopes Monkey Trial, and Lewis and Clark explore the dangerous West.

Othniel Marsh and Edward Cope become bitter rivals while creating Paleontology and Penzias & Wilson discover the sound of The Big Bang.

The LAPD is formed to stop the city from devolving into chaos, Rin Tin Tin becomes a global superstar, and William Mulholland figures out how to bring water to Los Angeles.

Carl Sagan and Ann Druyan fall in love over a golden record, Wernher Von Braun pioneers rocket science, and Alexey Leonov becomes the first man to float in space.

A lawyer defends the lives of rats in court, Henry Bergh establishes the ASPCA, and a horse that can solve math problems leads to advances in the field of psychology.

John F. Kennedy’s doctor administers him meth for his back pain, and Dr. John C. Lilly takes LSD while studying the intelligence of dolphins.

Journalist Maurine Dallas Watkins writes a play about Chicago’s infamous Murderesses’ Row, and Mata Hari goes from exotic dancer to double agent during World War I.

Larry Walters pilots a balloon-suspended lawn chair, Phineas Gage survives an iron rod to the brain, and the Greenbrier Ghost’s testimony is used in court.