While holiday shopping, Barnes and Jess are caught in the middle of a mall shooting, with the exits rigged so no one can escape. Also, Gaines, Hana and Ortiz try to help from the outside, knowing their team's family members are inside and at risk.

The team's new leader, charming but formidable Special Agent Remy Scott, takes charge as they investigate a series of homicides tied to a forbidden love between a young teen and her older boyfriend.

After Hana is kidnapped while trying to help a young girl in peril at a rest stop that's on the way to her sister's house in Connecticut, Remy and the team pull out all the stops to find her.

When a rising star athlete is found violently murdered, the team chases after one of her teammates and his girlfriend; Remy reunites with a true crime show producer from his past.

After two agents from the Bureau of Land Management go missing while executing a land seizure warrant in Wyoming, the Fugitive Task Force heads west to track them down in an unwelcoming county; Hana receives a threat.

A local FBI case involving two murdered women and a sea of powerful men turns into a manhunt for the dangerous leader of a far-reaching criminal enterprise. The crossover starts on FBI S04E01 All That Glitters (I). It continues on FBI: International S01E01 Pilot (III).

The team investigates the murder of a professional basketball player’s wife, who was a famous lifestyle guru. Also, Kristin and her ex-husband grow closer, and Special Agent in Charge Isobel Castille checks in with the team on the high-profile case.

The team hunts for a young man who is using napalm-style bombs to attack his targets. Also, with Tali away, Jess and Sarah begin to adjust to their empty nest.

The Fugitive Task Force chases a killer who plays a twisted game of cat and mouse with his victims. Also, Hana shares something personal about herself with her new roommate, Ortiz.

The team searches for a notorious Colombian drug lord after he escapes from a U.S. prison. Also, Kristin begins to open up to her ex-husband about her past.

The team searches for a businessman wanted for murder and an embezzlement scheme. Also, Jess takes advantage of his empty nest to properly court Sarah.

Remy and the team investigate the homicides of two Army veterans in a murder spree connected to their time in Afghanistan.

The team goes after the killer of a man in witness protection but finds there’s more to the case than meets the eye. Also, Remy is challenged by what he discovers when he reconnects with his mother, Betsy, in person.

The team chases an oligarch who goes on a terror spree in New York City in a desperate attempt to escape his impossible situation.

After a heist in the Diamond District leaves three dead, the team's search for the fugitives reveals a dangerous connection to Kristin’s undercover past in Miami.

When three prosecutors are assassinated outside a bar in their small Arkansas town, the team is called in to determine if this was a personal vendetta; Ray feels compelled to help a woman and her young son combat an injustice.

When a celebrity child psychiatrist is kidnapped by the relative of a former client, the team races to track down the perpetrator and learns what really happened to the psychiatrist's client; Kristin confronts her deep-rooted trauma.

The team is thrown for a loop when they discover the abductor of a disgraced state police detective is connected to someone from a recent case.

As the team chases after the suspects behind an explosion at an Ohio energy plant, they are led towards a major crypto company with enemies looking to take it down; Remy and his sister close a chapter in their lives.

The witness Remy and Kristen are visiting in prison is put in danger when a riot breaks out, leaving the staff and visitors held hostage by two murderous gangs.

After a deadly fire at an arcade, the team discovers the blaze was just the first step in an intricate plan to exact revenge on one of the victims. Also, Hana rejoins the team, finding new adjustments in all aspects of her life.

The team must track down a murderous member of the incel community targeting those he believes never give him a chance. Also, Barnes, Hana, Ortiz and Kristin deal with their grief in the wake of Jess’ death.

After taking down a terrorist, the FBI and their Fugitive Task Force partners turn their attention to the terrorist’s wife who escaped with one million dollars and is determined to follow through with her husband’s deadly plan. Also, LaCroix’s daughter, Tali, is taken away by ICE, but as Jess tracks her down, he realizes her detainment may be more than just random coincidence. The crossover starts on FBI S02E18 American Dreams (I).

After a manipulative student commits murder in a fit of jealousy, the team races to capture her before she escapes across the border. Also, Jess teaches Tali how to stand up to bullies, on the second of two new back-to-back episodes

When a case of cyber-stalking escalates to multiple murders, the team must track down a hacker who will stop at nothing to get revenge on those he believes have wronged him. Someone from Hana’s past offers her help on the case, but at a price she’s not willing to pay.