As a part of Mother's Day mother-daughter bonding, Kim and her mother Dr. Possible decide to foil Drakken's latest scheme together. Drakken, on his part, is forced to deal with the presence of his mother while he attempts to steal a batch of Syntho-Plasma.

When Kim and Ron go to stop Drakken's latest plot, they accidentily get their brains switched between their bodies. Now they must stop Drakken's plans, and deal with each others lives.

Kim is forced by her dad to join a club for small children that he leads, much to her dismay. Meanwhile, Monkey Fist plans to steal a very special monkey to fulfill a prophecy.

Ron realizes that he is not technically a man yet, but Kim tells him that he is. Meanwhile, Kim and Ron must stop a villian from stealing a special ring.

Kim accidently turns Ron into a selfish jerk with a new haircut, all while two new villians begin their new evil hobby.

When Kim is tardy when going to class, she is sentenced to detention. Meanwhile, Drakken and Shego start their next evil plan.

When Kim's parents chaperone a school ski trip, she is greatly humiliated. Meanwhile, a mad geneticist threatens the trip.

Kim and Ron visit a strange man by the name of Lord Monty Fiske, however, they soon realize that there is more to him. Meanwhile, Kim's geeky cousin comes to Middleton.

Kim retrieves a ring-like object from a trade, but she soon learns that it is not actually a ring. Meanwhile, Kim wants to go to a party, but Ron wants her to go with him, and her parents with them.

On their way to a cheer competition, Ron and the cheersquad get stranded, but Ron soon realizes that the whole thing could be a set up from an old enemy.

Kim and Ron get a part-time job at Bueno Nacho, while Drakken and Shego start a cheese related scheme in Wisconsin

When Kim and Ron accidentally show that a stunt show is all staged, the host wants revenge. Meanwhile, the entire school thinks Kim likes Brick Flagg.

Kim ruins her clothes during a mission, and now must buy from Smarty Mart. Meanwhile, Frugal Lucre attempts to take over the internet.

Ron goes to ridiculous lengths to grab the attention of a pretty girl at the theater. Meanwhile Kim uncovers a conspiracy at the Space Center involving top secret technology, battle robots, and a disgruntled former employee. In the process of solving the mystery, she is suspicious of the idea of a seemingly innocent being the culprit responsible.

When Señor Senior Sr. becomes disappointed in the way his son’s villainy is handled, he decides to hire a tutor to ensure his son’s success; which turns out to be Shego. Meanwhile, a hopeless Kim is stuck on Home Economics with Ron but when Ron becomes an expert chef while Kim can’t cook a single thing, Ron is chosen to help Kim out. Can Kim overcome her predicament or is this one sitch that she cannot escape from?

Kim and Ron are taking Drivers Ed, which most of the students are nervous but Kim remains confident that she’ll do a good job. However, when she chokes up and fails the initial test, she soon learns that the pressure of the test is far greater than any foe she has fought. Meanwhile, Dr. Drakken has kidnapped a scientist who specializes in artificial intelligence, Kim gets a visit from an unexpected guest that may be able to help her out.

Kim's canon of villainous foes go hunting for Naked Mole Rat when Rufus becomes the carrier of a much-coveted micro-decoder … all while Kim is pet-sitting for Ron.

It’s career day and Kim expects to be paired up with her mother. However, when Bonnie gets teamed up with her instead, Kim gets stuck with a janitor who seems too dedicated to his job. Meanwhile, Ron gets paired with a secret agent and gets a plethora of unique gadgets to try out. However, with Dr. Drakken stealing a weather machine so he can flood Canada, Kim may just realize that her mentor may be more useful than she first thought.

When Middleton High School participates in a student exchange program, Ron is selected to go to a school in Japan while a student named Hirotaka is chosen to come to Middleton. Ron finds out that the school he was assigned to visit is a secret ninja school while Kim and Monique eventually start crushing on Hirotaka. However, when Lord Monkey Fist steals the Lotus Blade from Ron’s sensei, it’s up to Ron to save the day; though without Kim’s help.

Drakken and Shego attempt to breach Area 51 with a gigantic poodle while Ron uses the attack to shoot his monster movie.

To help his son's ongoing quest to become a pop sensation, Senor Senior, Senior kidnaps the Oh Boyz band to blackmail the record company. The plan backfires when Ron winds up captured along with the group. The record executive, finding the Oh Boyz' disappearance to be a profit windfall, is in no hurry to help so Kim must find Ron and the others on her own.

While Kim and Ron are at the Museum, she discovers that one of her ancestors was a thief and she decides to figure out what really happened in order to clear her family’s name. However, after a bunch of bizarre coincidences connects the events on that day with that of Wade and Dr. Drakken’s ancestors as well, she soon believes she may be close to figuring out what exactly happened to cause her ancestor to get framed, though Ron keeps feeling that something about their predicament just doesn’t feel right.

While trying to stop Dr. Drakken, Kim gets into a fight with Shego in which they accidentally get a microchip attached to each of them that can control their emotions. However, when Ron accidentally picks up the control device instead of Kim’s communicator, he thinks it’s a game and he inadvertently controls Kim and Shego’s moods, in which he puts on romance mode before he and Kim go to school. Ron must now deal with Kim’s sudden advances towards him while trying to determine what he should do about the situation, all the while Drakken is dealing with a suddenly love-stricken Shego.

When Kim and Ron go to stop Professor Dementor from stealing from a top-secret research laboratory, Ron inadvertently catches Dementor’s “Bondo-Ball” in his pocket, which he accidentally triggers later that day. When Ron rushes into Mr. Barkin and gets stuck to him, he rushes to warn Kim but discovers that she is already stuck to Bonnie. Now Kim and Ron must work with their enemies while trying to cope with what occurred to them and there’s still Professor Dementor to worry about; but will Kim and Ron gain any insight towards the life of their enemies through the ordeal?

Kim goes with her brothers and her father to visit her uncle’s ranch in Montana, in which Ron decides to go along because he figures that he’ll be able to be lazy at the ranch. However, when Dr. Drakken decides to hold a convention for the smartest people in the world, he uses his “silly hats” to make them ignorant so that he may become the best genius in the world. It’s up to Kim to save the day once again, though she soon learns that she may need help from her family; especially her cousin Joss who considers Kim her idol.