On their way to cheer camp, the squad again finds itself at Camp Wannaweep for the Spirit Stick Competition. Kim deals with having an obnoxious Bonnie.

When Kim catches a cold from her brothers before a mission, she soon discovers that it’s hard to save the world when you’re not feeling well. Dr. Drakken and Shego exploit the moment to steal a laser from the research lab Kim is guarding. However, when Kim’s sickness begins to spread, a series of events occurred that not even she could expect.

Drakken kidnaps Ron when he believes he is a super genius because Ron’s schoolwork has recently been completed by a brain ray-enhanced Rufus; while Dr. Drakken attempts to figure out the source of Ron’s knowledge, it’s up to Kim and Rufus to help rescue him and foil Drakken’s scheme.

After both Ron Stoppable and shallow Camille Léon leave their beloved pets behind during a fight, Rufus and Debutante go on an adventure, playing a little game of cat and mouse, traversing continents, and finding new friends, all to find their respective owners.

When Ron gets a scare when he thinks he is getting fired, his boss suprises him by making him watch his son instead. Meanwhile, Frugal Lucre gets let out of prison, and immediately goes back to Drakken. They soon begin a new plan together, much to Drakken's disgust.

When Dr. Director at Global Justice decides that it's the "Ron-ness" that's Kim's secret to success, Ron goes under the microscope. Unfortunately, this means being stolen by the lackey-intolerant Gemini, Dr. Director's older twin. Global Justice, Kim, and Rufus take on Gemini's fist of fury (and Pepe the neurotic Chihuahua) to recover the Ron Factor.

Kim, Ron and the Possible family head to Florida to help Kim's grandmother unpack at her new home. Can Kim fight against her grandmother's over-protectiveness? Meanwhile, Drakken and Shego accidentally create an army of old people instead of teens, and Kim's Nana is one of them. Can Kim fight her own Nana?

Ron is sucked into the cyber game world of Everlot as he attempts to impress Zita. The whole gang duels Malcolm the Wraithmaster LotR-style, with a little help from a not-so-naked Tunnel Lord.

When Ron is volunteering to help the elderly by doing tasks for them, Ron is assigned to the house of Timothy North, an elderly man who has sent all volunteers away. However, Ron stumbles across the fact that Timothy North is really The Fearless Ferret, an old superhero who Ron adores; in which Ron is selected to become the new Fearless Ferret but he must keep his identity a secret, even from Kim. Though when The White Stripe comes to fight the new Fearless Ferret, Ron discovers it’s more difficult than he expected; while Kim is busy trying to figure out why Ron is behaving strangely.

The weather outside is frightful when evil, toxically-mutated snowmen terrorize Middleton.

In the spirit of the season, Drakken, Shego, Ron, and the Possible family put their differences behind them to share Christmas in the Arctic ... of course, only after several action-packed battles and confrontations.

When a recent string of thefts cause a global shortage on a certain type of doll, Kim decides to investigate, despite the fact that she already has a lot of extra-curricular duties to perform. When she finds out that the Bebe-bots are back and bent on creating an army of their speedy species, with Bonnie as their queen, Kim must rely on some recently acquired experimental shoes in order to save the world; though that isn’t going to stop her from doing a few of her extra-curricular tasks along the way.

Ron signs an unwilling Kim up for the school talent show after Bonnie announces her intent to crush any competition. Her plans to sing are interrupted when Wade begins acting erratically and orders Kim and Ron to recover teleportation technology from Professor Dementor. Technology, she suspects, that may have not been stolen after all.

On their trip to Go City, Ron and Kim come across a villain named Aviarius who is seeking the power of another hero. However, when Kim inadvertently winds up with the a hero named Hego’s powers, she soon learns that the only way to restore what isn’t hers and to help stop a mad man may be to team up with her deadliest foe; Shego.

When Kim is sprayed with some pollen that causes her to vanish more and more each time she blushes, she must stay at home while Ron and Wade work together to find the cure. However, when Josh Mankey asks Kim on a date, she risks her life to go out with him; though Drakken and Shego take notice of her foolishness and exploit the opportunity to make it one of the most embarrassing nights of her life.

Kim, hoping not to be landed with Ron as her science project partner, instead gets a brainiac who won’t let her do anything at all. Monique gets Ron and quickly becomes exasperated by his trademark laziness. Meanwhile Drakken charms DNAmy into creating a vicious Komodo dragon.

When trying to save a scientist from Dr. Drakken’s secret arctic base, Kim and Ron are hit with a truth ray which forces them to speak the absolute truth about every issue. Kim soon discovers that this is a huge embarrassment while Ron is enjoying his newfound truth potential, but can they get through the day without causing themselves huge problems?

After a series of high tech robberies, Kim tries to stop the plot of a rogue scientist turned rocking trucker, with a little help from a new friend, Felix.

When Dr. Drakken is ordered by his mother to look after his cousin which turns out to be Motor Ed, Drakken and Motor Ed work together to complete a “Doomvee”, which is a Humvee that is full of superior weaponry. Meanwhile, Kim is feeling alone because Ron is spending the weekend with Felix instead of her, which causes her to become desperate because she needs some social interaction. Kim attempts to hang out with Ron and Felix despite the fact that she hates doing whatever they do, but when Dr. Drakken and Motor Ed steal Felix’s wheelchair, they work together to see if they can retrieve his wheelchair back and put an end to their evil plan.

When Mrs. Hatchet discovers that Kim has an overdue library book, KP's cheerleading activities are suspended. Ron realizes that he lost the book, and he has to retrace his steps through the last few missions he and Kim went on to save Kim from...library lock-up!

Kim is forced by Ron to join the race for class president, but when they bring home a spoiled Prince who is in danger, he runs against Kim.

Kim plans on throwing her cousin Larry a surprise birthday party, but she has to keep him busy until the party is ready. Meanwhile, Dementor enlists the help of his brother-in-law to steal Kim's battlesuit.

When a diamond is stolen, all the signs indicate that a Lithuanian Wolfhound breeder named Falsetto Jones is the thief. Kim and Ron enter Rufus into a dog show as a Peruvian Hairless in hopes of confronting Falsetto and getting the diamond back, though will Rufus actually be able to play the part?

Kim catches a nasty cold from the Tweebs, but still accepts a mission to guard a mysterious machine. After Drakken and Shego steal the device, her mother insists that she stay in bed to rest while Ron and then the Tweebs take up her duties. By the time matters are resolved, everybody on both sides of the conflict has caught the cold.

Naco royalties make Ron a tremendously rich and wealthy multimillionaire with ninety-nine million dollars, which he then proceeds to squander on a posse of fake friends and spending binges. Out of greed, Dr. Drakken attempts to steal Ron's newly acquired fortune and wealth to complete his latest doomsday scheme.