When Adam, Bree and Chase forget to invite Leo to his surprise birthday party, they must make it up to him, so they take Leo into the ultra-cool virtual mission simulator and show him what it's like to be bionic.

The trio has switched places with robot versions of themselves, sending the robots to the remote lab. Tasha is afraid of Leo's attachment to the 'robots' and convences Donald to send them to the scrap yard. Leo heads off to rescue his new friends. On their return home Donald agrees to let them stay and learn about normal human life if they and Leo can keep their bionic powers a secret.

On the Lab Rats' first day of school, all goes awry when Chase is confronted by a football player and his "Commando App" is triggered, transforming him into Spike, an unruly drill sergeant. When Spike defies the school principal, she pits the Lab Rats up against the football team to battle it out for the coveted cafeteria table

The Lab Rats get their first mission to stop Davenport's hi-tech super fast train from speeding out of control.

When Davenport's prized invention, a super strength and laser empowered exoskeleton suit, malfunctions, after Chase reverses its controls, to get back at Leo for stealing his presenting job. However, it ends up unleashing destructive power on the household, making Leo's grandma even more suspicious of the family.

When Chase refuses to admit that Adam has good ideas Adam decides to run against him for student of the semester. Meanwhile, Leo takes advantage of Bree's super speed and starts using her as his personal taxi.

Leo & Adam team up for the school fitness challenge expecting Adam's bionics to be his secret weapon; the plan backfires when they end up going head-to-head in the finals. Meanwhile, Bree and Chase use their bionic abilities against one another.

Leo borrows Davenport's helicopter to take Janelle on a daring date. Bree gets her own room and Adam and Chase are excited to have a room to themselves. But things get out of hand and Chase divides the room up.

Future Leo travels back in time to tell Leo, that Chase, Bree, and Adam won't make it to the future, and Leo is the only one who can save them.

Adam, Bree and Chase switch their bionics but things end up not the way they think when they can't handle it anymore.

Leo is left alone to care for the Lab Rats, but things quickly go wrong when he plays with a new gadget that glitches Adam, Bree, and Chase.

Adam, Bree and Chase learn about chores and earn allowance for the first time. To raise more money, they host a yard sale and accidentally sell an antique jewelry box that Davenport was restoring for Tasha.

Tasha takes the entire family on a nice 'tech free' beach weekend in the RV, but when Davenport discovers a solar flare headed in the Earth's direction, he secretly enlists the help of the Lab Rats.

In order to fight Trent's bullying, Leo signs up for a one-on-one basketball game against his rival.

When Leo accidentally messes up Eddy, an evil demon Teddy replaces him.

Adam, Bree, and Chase are caught on Principal Perry's surveillance camera using bionics.

Leo is blamed for breaking Marcus' guitar.

Chase accidentally discovers that he has a hidden ability - telekinesis.

Sebastian has secretly formed an evil rebellion to get revenge on the Lab Rats for destroying his father. Meanwhile, Leo is trapped with the other bionic people who also want revenge, but Leo manages to convince Spin and Bob to help him, and, in the end, Sebastian is defeated, his rebellion is brought down, and he and his comrades are taken to a facility. Meanwhile, Donald successfully convinces the others that he has the best interest for them at heart while Adam still blames Chase for everything that happened after the rebellion is over.

Sebastian has secretly formed an evil rebellion to get revenge on the Lab Rats for destroying his father. Meanwhile, Leo is trapped with the other bionic people who also want revenge, but Leo manages to convince Spin and Bob to help him, and, in the end, Sebastian is defeated, his rebellion is brought down, and he and his comrades are taken to a facility. Meanwhile, Donald successfully convinces the others that he has the best interest for them at heart while Adam still blames Chase for everything that happened after the rebellion is over.

After sneaking some students off the island and to the mainland, the Lab Rats accidentally leave Spin and Bob behind and must retrieve them before Donald finds out. Meanwhile, Donald tries on Chase's mission suit and he and Leo scramble to get it off before Chase gets home.

When suspicious events happen overnight on the bionic island, everyone is convinced a new threat has emerged. However, this threat is revealed to be Leo, when his bionics glitch because Douglas never gave Leo a capsule.

Adam brings a dog back to the island and Douglas reveals that it's his old dog, Otis, who Douglas made bionic in order to save his life when Otis was injured. Chase turns out to be allergic to dogs as he starts sneezing, so Douglas says that Otis has to leave, but he and Adam actually hide the dog. Meanwhile, Leo gets a new smartphone application assistant named Shelly, with whom he has fallen in love.

The Lab Rats are on a mission to save people from a wildfire; when the people start to chant Adam, Bree, and Chase's names, Leo gets jealous and wants to become known. Douglas gets put in charge to develop a new technology for the academy, but can only come up with things that can hurt the students.

Adam and Chase each lead their own student groups against each other in a series of simulated exercises that will evaluate both student and mentor performance. However, after Chase's group fails at defeating the exoskeleton and defusing a virtual bomb, Chase decides to find a way to cheat and win.