When Matty and the team search for a former government tech who stole classified intel and has been evading capture, they reunite with the Coltons, the family of bounty hunters, who are pursuing the same man for different reasons.

Angus MacGyver and Jack Dalton, special agents for the Department of External Services (DXS), join forces to recover a missing bioweapon that has the ability to destroy hundreds of thousands of people with one single drop.

MacGyver and the team attempt to rescue Sarah, Jack’s former CIA partner/ex-girlfriend who went missing in Venezuela after she obtained evidence to take down an international arms dealer.

MacGyver and the team are in Malaysia to extract a terrorist groups’ money man, Ralph, who holds key intel to an impending attack. But the mission goes south when the man is shot, and now, with only a driver’s license and hand sanitizer available, MacGyver must keep Ralph alive in order to learn the terrorists’ plans.

MacGyver and team are asked to solve a locked-door mystery when a man working inside a remote, ultra-secure international seed vault disappears.

Mac and Jack attempt to rescue a billionaire’s son after he is kidnapped by a former Navy SEAL who uses an EMP weapon to cut off power and communication lines to the Shanghai skyscraper where the boy lives.

During COVID-19’s first stay-at-home order, as Mac, Bozer and Riley quarantine together, they try to stop a crime in progress at their neighbor’s house. Also, Russ’ romantic fling takes on a longer and more complicated turn when they quarantine together.

MacGyver, Leanna, Riley and Bozer pose as honeymoon couples at a resort in order to gain information about a Serbian war criminal from his newly married son. Also, Bozer wonders if Matty knows about his relationship with Leanna, and Jack recruits Elwood to help him break into Matty’s home.

Mac and Jack partner with older versions of themselves, a Russian bomb programmer and his estranged handler, to shut down a Soviet-era warhead in Moscow. But when the antiquated computer needed to disable the warhead becomes inoperable, Mac must find a way to fix it with only duct tape and wire in time to prevent a new Cold War.

Mac is placed inside a fake prison cell with a top Codex operative, The Merchant, in order to gain his trust and get intel on their next move.

Using only an armrest, a curtain rod, and a toothpick, MacGyver must fix a sabotaged train in order to protect a whistleblower who has proof that her boss is selling weapons to U.S. enemies.

With only a chisel and matchbook, MacGyver and team must defend themselves the U.S. embassy workers in Latvia from extremists who are attempting to retrieve their leader. Also, Bozer faces a big decision now that he knows who Mac really is.

On the way back from capturing a war criminal, Mac and Jack’s helicopter crashes in a remote area of Kazakhstan, injuring their pilot and allowing their prisoner to escape with Jack’s gun. Using a large blade and a water bottle, MacGyver must get help as the pilot’s condition worsens and before the war criminal takes them as prisoners.

MacGyver and Riley, with the help of Vasil, a distraught father, must find a way to drive a tanker filled with liquid oxygen through a region occupied by rebels and deliver it to a children’s hospital before they run out. Also, Riley helps MacGyver decide whether or not to allow his father back into his life.

Matty sends MacGyver and team to Ghana to recover a hard drive from an e-waste landfill that is run by a powerful and violent man. But when Matty refuses to reveal what’s on the drive, other than a mysterious file called “Dragonfly,” the team speculates about what could be so important to her.

After a surprising introduction to Phoenix’s newest recruit, Desi, MacGyver and team are assigned to escort and protect an ATF (alcohol, tobacco, firearms) gun-sniffing dog who has a bounty on his head, only to discover they’re not the only ones crashing the weapon drop.

When Nicholas Helman resurfaces to carry out a killing spree, the Phoenix is forced to get help from the one person who knows him best… his protégé, Murdoc.

After Oversight is almost killed in a bombing, he recruits Mac to help him find the suspected bomber, Mason. However, when Mason reveals he didn’t plant the bomb, the three team up to track down Codex, the shadow organization that set them up. Also, Mac meets his aunt Gwendolyn.

Using only a wrench and rope, MacGyver must diffuse a bomb set near the United Nations by his old nemesis, “The Ghost”, a notorious criminal whose work killed his mentor, and track him down before he strikes again.

MacGyver is tasked to go undercover as an inmate in a maximum security prison to break out El Noche, a notorious drug kingpin, using only batteries and salt, and track him to his cartel's secret location and dismantle it.

Mac and the team have no time to reminisce while visiting Mac’s and Bozer’s hometown when they immediately start searching for a kidnapped prodigy from Mac’s old middle school, Valerie.

Using a fish scaler and some fishing wire, Mac and Jack must track down a corrupt FBI agent who has framed a man for murder. Also, everyone on the team is terrified to get their first performance review from Matty, their tough new boss.

While tracking down the dangerous fugitive Aaron Deckard, Mac and Jack face the notorious Colton family of bounty hunters who already kidnapped their mark. Also, Bozer and Riley try to hack into Jack’s CIA file to find out about his history with Matty.

Mac, Jack and Riley set out to find a mobster-turned-informant after he’s kidnapped and taken to Chernobyl by an international crime boss who’s worried he will deliver incriminating information to the CIA. Also, Bozer struggles to keep a secret from Matty.

As Mac and the team investigate the suspicious death of Dawn's CIA supervisor, the evidence leads to a dirty CIA agent and a massive counterfeiting ring.