During an appearance on a typically terrible morning radio show, Marc declares the medium dead, and the future belongs to podcasting. However, when he meets a largely ignored radio genius, he has a new respect for some DJs.

As Marc's career reaches new heights, he is visited by an old acquaintance, desperate for a helping hand. After the comic passes away, Marc is forced to confront the reality that his success could disappear in an instant.

Marc's mom comes to visit. He wants to avoid her and pawns her off on a friend's Dad. The plan backfires when the older couple hit it off too well and Marc has to parent his Mom through an STD scare.

When Marc accidentally steals a joke from another comedian, he feels guilty. That guilt is put to the test when the comic insists Marc help his career in return.

Marc is dreading an upcoming road trip. He's tired of doing the same old material and is anxious at the thought of writing new stuff but his anxiety reaches a peak when he discovers a sore that he believes to be mouth cancer.

Marc hits it off with Rachael Harris by comparing their bad relationship scars. When Marc pursues her, she wants him to prove he's over his anger issues by joining her yoga class.

Marc is riding high, his career is taking off and his relationship with Jen seems to be going well. However, Marc turns out to be his own worst enemy as he sabotages a TV guest spot and ruins his relationship at the same time.

Marc is dealing with the finality of his relationship with Jen but is sidetracked by his missing cat, Boomer. He goes door to door through his neighborhood, looking for his cat, while at the same time learning how his neighbors deal with loss.

Marc and Jen enter couples therapy with married therapists but instead of helping, it exacerbates their issues. After Marc feels wronged by the therapists, he ends up putting a dent in their "perfect" relationship.

When Marc's brother shows up on his doorstep after leaving his life, both mom and dad show up to "help." Things are immediately dysfunctional but when podcast guest David Cross gets everyone stoned (except Marc), they hash out their issues.

Trying to lead a simpler life, Marc immerses himself in his vinyl-collecting hobby but a chance encounter with a woman he meets in the record store parking lot snowballs into just the kind of chaos he’s been trying to avoid.

Newly single Marc tries to start a no-strings sexual relationship with a sex buddy from years ago. He reasons that a less emotional attachment is exactly what he needs but soon learns that it's easier said than done.

Marc is annoyed that none of his old pals can hang anymore on a regular basis. Although after bonding with Ray Romano, Marc pursues a friendship, ignoring Kyle's warnings that Romano is on a different level.

Marc discovers the source of the awful smell stinking up his house. His podcast guest, Denis Leary, calls Marc’s masculinity into question, causing him to over prepare for removing the dead animal from under his house. Marc’s mom sets up a meeting between him and a family friend who becomes Marc’s eager new assistant.

Tired of dating younger women, Marc decides to date an age-appropriate woman he meets at a coffee shop. She's smart and sexy, but things go south when she puts Marc in the hot seat by having him interviewed on her son’s podcast.

Marc meets up with an old college friend who has become a mainstream sell-out filmmaker. He offers Marc a dubious part in his upcoming movie. As Marc considers the part strictly for the health benefits, he pictures how his life might look had he made different choices.

Marc's former fling moves in temporarily with Marc after being evicted. She invades Marc’s boundaries and tensions go through the roof. He questions her hoarding tendencies and believes she lied about being kicked out of her previous apartment. Luckily, an unexpected visitor intervenes as their fighting hits a crescendo.

Marc’s estranged dad, Larry shows up in an RV at Marc’s house with yet another foolproof scheme to get rich quick. Marc and Larry air their grievances towards each other and a power struggle ensues. Additional guest stars: Andy Kindler, Pete Holmes and Jeff Garlin.

At an AA meeting, Marc becomes a sponsor to Manny, an ex-con just out of prison. Marc finds himself in over his head while he accompanies Manny to his old haunts.

Marc receives an explicit photo from a female fan, who suggests a weekend of no-strings-attached sex at an out-of-town comedy festival. Marc obliges and goes through the full six stages of a relationship within a matter of two days.

Marc freaks out after learning his “Sexfest” fling plans to move too close for comfort. After Marc rejects her, she sets her sights on the next best thing and comes between Marc and his assistant Kyle.

In denial about his current situation, Marc is reluctantly convinced by his friends to enter rehab.

Marc takes a writing position on Dave’s new TV show.

Marc looks for work in the new town and attempts to get close to his baby.

Marc tries to convince Shay that he can be a positive force in her son’s life.