Marc is tormented by an abusive fan on Twitter. With his podcast guest Dave Foley in tow, Marc decides to teach one internet troll a lesson.

Marc finds out from his podcast guest and friend, Illeana Douglas, that his ex-­‐wife is having a baby. Illeana sets Marc up on a blind date with a nice girl, but he falls for a raunchy dominatrix instead.

Marc’s estranged dad, Larry shows up in an RV at Marc’s house with yet another foolproof scheme to get rich quick. Marc and Larry air their grievances towards each other and a power struggle ensues. Additional guest stars: Andy Kindler, Pete Holmes and Jeff Garlin.

At an AA meeting, Marc becomes a sponsor to Manny, an ex-con just out of prison. Marc finds himself in over his head while he accompanies Manny to his old haunts.

Marc receives an explicit photo from a female fan, who suggests a weekend of no-strings-attached sex at an out-of-town comedy festival. Marc obliges and goes through the full six stages of a relationship within a matter of two days.

Marc freaks out after learning his “Sexfest” fling plans to move too close for comfort. After Marc rejects her, she sets her sights on the next best thing and comes between Marc and his assistant Kyle.

Marc's former fling moves in temporarily with Marc after being evicted. She invades Marc’s boundaries and tensions go through the roof. He questions her hoarding tendencies and believes she lied about being kicked out of her previous apartment. Luckily, an unexpected visitor intervenes as their fighting hits a crescendo.

Marc discovers the source of the awful smell stinking up his house. His podcast guest, Denis Leary, calls Marc’s masculinity into question, causing him to over prepare for removing the dead animal from under his house. Marc’s mom sets up a meeting between him and a family friend who becomes Marc’s eager new assistant.

Tired of dating younger women, Marc decides to date an age-appropriate woman he meets at a coffee shop. She's smart and sexy, but things go south when she puts Marc in the hot seat by having him interviewed on her son’s podcast.

Marc meets up with an old college friend who has become a mainstream sell-out filmmaker. He offers Marc a dubious part in his upcoming movie. As Marc considers the part strictly for the health benefits, he pictures how his life might look had he made different choices.

Marc is annoyed that none of his old pals can hang anymore on a regular basis. Although after bonding with Ray Romano, Marc pursues a friendship, ignoring Kyle's warnings that Romano is on a different level.

Marc invites his ex-wife onto his podcast after finding out that she has written a book; memories bring up unresolved issues.

When Marc and his old radio co-host Sam Seder are threatened with a lawsuit from a patent troll they organize a podcasters-only meeting to plan their retaliation.

Marc's brother invites him to speak at his company’s corporate retreat, which resembles more of a Jimmy Buffet fan-club convention than a professional get together.

Marc and Jen enter couples therapy with married therapists but instead of helping, it exacerbates their issues. After Marc feels wronged by the therapists, he ends up putting a dent in their "perfect" relationship.

Newly single Marc tries to start a no-strings sexual relationship with a sex buddy from years ago. He reasons that a less emotional attachment is exactly what he needs but soon learns that it's easier said than done.

Marc's novelist pal asks him to guest lecture at the college where he teaches, but their friendship is tested when sparks fly between Marc and the TA.

Faced with pressures from his talk show pilot Marc goes on anti-depressants, which create some dubious side effects.

With his talk show pilot approaching, Marc gives up nicotine gum and caffeine, and tries to get into shape with the help of pro wrestler, CM Punk. The stress of his new regimen leads to a more serious problem.

After training with pro-wrestler CM Punk, Marc’s back goes out and he is prescribed Oxycontin. Things take a turn for the worst, but everyone tries to keep Marc on the right path as he prepares for his talk show premiere.

Marc checks into rehab and is forced to room with an annoying young addict.

When Marc's brother shows up on his doorstep after leaving his life, both mom and dad show up to "help." Things are immediately dysfunctional but when podcast guest David Cross gets everyone stoned (except Marc), they hash out their issues.

Trying to lead a simpler life, Marc immerses himself in his vinyl-collecting hobby but a chance encounter with a woman he meets in the record store parking lot snowballs into just the kind of chaos he’s been trying to avoid.

Marc decides to search for a cure for his anger problem.

After chafing under Shirley’s oppressive ‘tranquility,’ Marc jumps at the chance to spend time with the sober-yet-wild Bobby Mendez.