Beth Harper, an absentee wife and mother who suffers a dramatic near-death experience and is revived only to discover that she now receives messages from God. As she warms up to her powers and begins dispensing advice that is astonishingly accurate, her husband Tom is skeptical and their teenage daughter Emily is horrified. Complicating matters even more, Tom's mistress Carly shows up to confront Beth about the affair and quickly gets a shocking surprise.

Beth and Tom visit a comatose Carly in the hospital. When they hit a squirrel on the way home, Beth becomes obsessed with saving it, going to great lengths to help the animal despite the objections of her husband and friends. Later - it becomes clear to all that the squirrel is a symbol of something much more important in Beth's life.

When Beth receives a message to "Honor thy Father and thy Mother," she decides she must earn her daughter Emily's respect and make some positive changes in her life.

When Tom reveals that he's up for a big promotion, Beth decides to host a dinner party for his boss Stephanie (Debra Wilson) and her officious assistant Randall (Michael McDonald) but she becomes distracted by a garage sale she thought she had cancelled. To make matters worse, she receives a divine message to get rid of many of their worldly possessions at the sale, so by the time everyone arrives, there is not much left of the family dining room. Luckily for Beth, Tom's boss is a woman who also knows a thing or two about speaking with the Lord.

When Beth learns that the hospital where Emily was born is being shut down, she decides she must try to raise funds to save it. Unfortunately for her, her friends are busy, distracted or not at all interested. Beth's overzealousness soon becomes a big problem, but when she receives a divine visit from the Almighty herself, she realizes that she really can make a difference without making everyone do things her way.

When Beth learns her friends and family were hoping to oust the elderly woman she wants to help from the neighborhood, she decides to go though with her plan anyway and makes a friend in the process.

Beth tries to make amends with friends she offended in the past; Tom must adjust to his wife's new ability to communicate with God.