Jo, Natalie and Blair are going to New York to see a Broadway play and a left out Tootie sneaks out to meet them in front of the theatre without Mrs. Garrett's knowledge. However, when Tootie doesn't find the girls she stops in a coffee shop across the street unaware she's about to get a dose of the downside of New York life.

It's finals week at Eastland and the girls are planning an all night study session. They soon find out that studying is going to be hard with so many distractions, including Blair and Jo's fears of the future in college and Natalie's fear of an upcoming Chemistry exam in which she must memorize the atomic symbols.

Constant squabbling between the girls prompt Mrs. Garrett to announce that the debt for wrecking the van has been paid off and they are all now free to move out and live in the dorms. However, the girls soon realize the living above the cafeteria is something they do not want to change.

Natalie has a big crush on Tim and has filled Blair's slambook with words of praise. However, in Blair's slambook instead of signing your name you sign a number, Natalie's number is 10. When Blair tells Tim who number 10 belongs to, Natalie is furious and wants revenge no matter who she hurts in the process.

As graduation day arrives, Monica is furious that Blair's father won't attend, Rose is furious at Charlie due to his sudden tranformation into a big spender and Natalie and Tootie are scared that they will lose Blair and Jo as friends when they leave for college.

Jo begins a pizza business with her mom's secret pizza recipe that has everyone's mouths watering, including a fraternity house that buys pizzas in bulk. However, the business begins running Jo and her workers, Natalie and Tootie ragged which leads Jo to make a business decision on how to make pizzas faster and cheaper.

Graduation has everyone rushing around and Natalie and Tootie are worried that their isn't going to be enough time for Jo and Blair to say goodbye, especially since Blair and Jo are at each other's throats, as usual.

Mrs. Garrett and the girls all become concerned about Blair's bizarre behavior, she's skipping class, dating nonstop and is out all night every night, all this just after a breakup with her first serious relationship, Cliff.

Blair is devastated when she learns that her boyfriend is into cocaine. Lisa Whelchel. Jo: Nancy McKeon. Kevin: Ryan Cassidy. Father Donovan: John Ingle.

The local drive-in theatre is closing and the girls decide to pay it one last visit on the final night it's open. However, chaos reigns when people begin to loot the theatre and Blair gets into a cat fight.

Natalie gets Blair a job at a Mexican restaurant where Natalie works. However, Blair snobby attitude gets her fired when she inadvertently insults the boss.

Both Blair and Jo head to New York to meet two old friends. Blair discovers her old friend, Dina, is the same old snob she's always been and Jo discovers her friend, Jesse, is the same old prejudiced bully she's always been. Blair and Jo soon realize their friendship is much more meaningful.

The girls have no plans for spring break until Natalie learns that her grandmother's condominium is available in Fort Lauderdale, where the boys are.

During an alumni weekend at Langley, Blair's mother and Jo's father bond which leads to Blair and Jo's fears of becoming sisters.

On the day Blair is to accept an award, she encounters two burdens. First, she's stuck babysitting her baby brother and second she becomes trapped in an elevator, where she learns an important lesson from a concentration camp survivor.

Mrs. Garrett and the girls visit New York and have lunch in a Italian restaurant where Natalie discovers something she never expected, her father romancing someone other than her mother. This prompts Natalie to debate whether or not to confront her father, out of fear of a divorce between her parents.

Natalie makes up a source for the topic of her newspaper article on abortion and if she doesn't reveal who the source is, she could be kicked out of school. However, little does she know, that their is someone at Eastland who could fill the shoes of the ""made up source""

On a dateless Saturday night, the girls cruise downtown Peekskill in hopes of finding Mr. Right. However, a string of bizarre events leads the girls to hideout in their car at a closed gas station.

Tootie's learning to drive and she's driving everyone bananas.

Burned by her journalism teacher's scathing criticism, Jo turns out a front-page story linking him to a drug bust.

Jo has become close friends with her English teacher, Gail, even inspiring Jo to think about becoming a teacher herself. However, Jo is disappointed to learn that Gail is leaving Eastland presumably for a job that pays more but the real reason she's leaving is nothing Jo ever expected.

Jo has been accepted at Langley College along with Blair but doesn't tell anyone that she has since she doesn't plan on going due to her and her parents financial situation. However, when she takes a trip home for the weekend, she learns that her entire family found out the truth and are now counting on her to do well.

While working at the campus radio station, Jo finds herself needing to fill 5 hours of air time. Things start off on a bad note, when she can't find a key to the record cabinet, which leads, Natalie, Tootie, Blair and Mrs. Garrett to come to her rescue.

After returning from their summer vacation, the girls discover that Edna's Edibles has burned down. This leads the girls to discuss rebuilding and opening up a new business.

Jo is offered a job at a major company which is tempting but this causes her to reevaluate her dream of becoming a teacher.