Jo, Natalie and Blair are going to New York to see a Broadway play and a left out Tootie sneaks out to meet them in front of the theatre without Mrs. Garrett's knowledge. However, when Tootie doesn't find the girls she stops in a coffee shop across the street unaware she's about to get a dose of the downside of New York life.

It's finals week at Eastland and the girls are planning an all night study session. They soon find out that studying is going to be hard with so many distractions, including Blair and Jo's fears of the future in college and Natalie's fear of an upcoming Chemistry exam in which she must memorize the atomic symbols.

Mrs. Garrett bails the girls out of jail and announces that they all have been expelled from Eastland. However, they can stay if they move in with Mrs. Garrett and work in the cafeteria. This prompts Jo's want to leave to become even stronger.

Constant squabbling between the girls prompt Mrs. Garrett to announce that the debt for wrecking the van has been paid off and they are all now free to move out and live in the dorms. However, the girls soon realize the living above the cafeteria is something they do not want to change.

Natalie has a big crush on Tim and has filled Blair's slambook with words of praise. However, in Blair's slambook instead of signing your name you sign a number, Natalie's number is 10. When Blair tells Tim who number 10 belongs to, Natalie is furious and wants revenge no matter who she hurts in the process.

As graduation day arrives, Monica is furious that Blair's father won't attend, Rose is furious at Charlie due to his sudden tranformation into a big spender and Natalie and Tootie are scared that they will lose Blair and Jo as friends when they leave for college.

The holidays bring joy to the girls when they all plan on going home for Christmas but when Jo's mother temporarily moves to Miami, Jo is stuck in Peekskill.

Graduation has everyone rushing around and Natalie and Tootie are worried that their isn't going to be enough time for Jo and Blair to say goodbye, especially since Blair and Jo are at each other's throats, as usual.

Jo and Blair have a hard time adjusting to college.

Ms Garret decides to re-open an abandoned department store and turn it into her own.

A strange man tells the girls that years ago a murder occurred in the shop. Later, when the girls see Mrs. Garret with a knife they assume that she's possessed by the murderer's spirit and is out to get them.

Natalie starts dating a black guy, and Tootie thinks that Natalie hates him because of his color.

Natalie gets Blair a job at a Mexican restaurant where Natalie works. However, Blair snobby attitude gets her fired when she inadvertently insults the boss.

One evening, a tired Blair falls asleep at the wheel and has a car accident landing her in the hospital with a gash in her for-head. This leads her to begin worrying about how her once ""perfect"" self will recover from this tragedy.

Blair is running for class president but things get out of hand when one of the candidates commits suicide.

Both Blair and Jo head to New York to meet two old friends. Blair discovers her old friend, Dina, is the same old snob she's always been and Jo discovers her friend, Jesse, is the same old prejudiced bully she's always been. Blair and Jo soon realize their friendship is much more meaningful.

On the day Blair is to accept an award, she encounters two burdens. First, she's stuck babysitting her baby brother and second she becomes trapped in an elevator, where she learns an important lesson from a concentration camp survivor.

Blair's after-hours visit with a professor reputed to be a womanizer stirs up a storm of vicious rumors on campus.

Mrs. Garrett and the girls visit New York and have lunch in a Italian restaurant where Natalie discovers something she never expected, her father romancing someone other than her mother. This prompts Natalie to debate whether or not to confront her father, out of fear of a divorce between her parents.

Natalie makes up a source for the topic of her newspaper article on abortion and if she doesn't reveal who the source is, she could be kicked out of school. However, little does she know, that their is someone at Eastland who could fill the shoes of the ""made up source""

The girls are shaken by the sudden death of Natalie's father and wonder how to ease her pain.

Tootie's learning to drive and she's driving everyone bananas.

Natalie jumps at the chance to do an inside story on ROTC and then learns she'll also have to jump from a plane.

Blair is sure that an old friend of hers', Harrison Andrews is going to invite her to a cotillion, however she is thrown for a loop when he invites Jo.

Natalie hits it off with Neil, a boy she meets at a dance and they later begin studying together. However, rumors are spread that Natalie and Neil did more than just study which brings on calls from a number of boys who want to study with Natalie. Natalie encourages these rumors when she goes out with the boys due to the fact that Blair, Jo and Tootie laughed at the notion that Natalie could be a sex symbol.