Sophia and Max come back from their honeymoon with no place to stay so Blanche, Dorothy and Rose put them up until they can find a place. Meanwhile, Sophia and Max decide to restart the old business Max had with Sophia's late husband, a pizza knish stand. However, Dorothy begins smoking again!

While Rose undergoes severe surgery, the girls try to entertain themselves with fond memories and laughter, only for Rose's daughter Kirsten to walk in on them enjoying themselves! Kirsten is spiteful of them and does not allow them to visit Rose. Kirsten visits Rose, who is near knocked out, and try to have a conversation...very comically as poor Rose is not altogether. With Rose going into surgery, Kirsten reconciles with the worried girls. At last, Rose is released and they all throw a surprise welcome home party for our lovable St. Olafian!

Blanche's uncle Lucas Hollingsworth is visiting but, to no surprise, Blanche is busy with a date. In order to be rid of his intrusion, Blanche tells Dorothy that he desperately wants to meet a woman of her intelligence. Dorothy agrees to see him but they both later learn that Blanche just lied to get rid of them and decide to get revenge by acting as though they're getting married, much to the dismay of Blanche. As a result, Rose decides she should move on to live with her daughter Kirsten to be the "Sophia of the household" as Blanche finally comes to terms with their idea to wed. Just as Lucas is about to reveal the truth, he decides to pop the question to Dorothy for real...

Dorothy accepts Lucas' proposal. The two plan to tie the knot two months later and on the way to the chapel, Dorothy takes a limo. However, this limo is driven by none other than Stanley Zbornak. The two share a rather comical but nonetheless touching moment together before arriving at the chapel. Down the aisle, along with Sophia, the girls think to themselves about the beautiful friendship they shared. Rose, Blanche and Sophia decide that the three of them should not depart and allow Dorothy on her way to Atlanta but she doesn't leave without sharing some final words with the girls...

Rose is upset when she has missed her high school reunion due to being sick, so Blanche convinces her, Dorothy and Sophia to crash a reunion held in Miami, posing as absentees from that school. Dorothy goes as the lame prom queen Cindy Lou Peoples, Blanche is the seemingly slutty Susan, Rose is the Korean exchange student Kim FongToi and Sophia is Mrs. Gonzales. With that, the girls mingle with their "former" classmates, only to realize that their counterparts lives are as dull as theirs, however, when the girls are found out by the guests...Rose has a heart attack!

Sophia befriends an old man on the boardwalk whom she becomes quick friends with. However, his strange behavior signals that he has a medical condition, Alzheimer's disease. Meanwhile, Blanche accidentally gives away Rose's teddy bear at a garage sale.

Blanche's latest boyfriend is a charming Cuban whom sweeps Blanche off her feet but she's not the only one when Blanche discovers he's been dating Sophia behind her back. Meanwhile, Rose takes a course taught by Dorothy in order to get a high school diploma.

This episode does a study in contrast, Sophia's busy day to Blanche, Dorothy and Rose's lazy day. While Sophia, organizes a band to raise money, volunteers at the hospital and battles return policies at the supermarket, Blanche, Dorothy and Rose sit around discussing what they should do that's constructive.

Blanche is determined to sleep with the one man who has refused her once in the past. Meanwhile, Rose claims to have seen a UFO and gets the Air Force involved.

Rose is running for St. Olaf Woman of the Year and with a little help from Blanche and Dorothy, altering her list of qualifications on the entry form, she's a sure winner. Meanwhile, a heat wave strikes Miami and the girls' air conditioning goes out.

At a baseball game, Sophia gets beaned. This prompts Stan to talk her into filing a lawsuit for payment for her severe injuries, which he gets her to fake. Meanwhile, Blanche and Rose prepare for roles in the play Cats.

The death of a close friend, Esther Weinstock, brings Sophia face to face with Esther's husband a man whom she vowed never to speak to again due to things that happened in the past. However, when Dorothy prompts them to make up they get a little to close and wind up in bed together. Soon after, they announce their engagement, something that Dorothy is totally against. Meanwhile, Blanche and Rose begin a Elvis Presley fan club.

The search is on for the missing winning lottery ticket that would give the girls $10,000. The girls had put it in the pocket of an aviator jacket, which Sophia mistook as an item to go to a thrift shop. The search leads the girls to the thrift shop then to a celebrity auction and finally to a homeless shelter.

Stan breaks the news that he's engaged to be married something Dorothy at first seems to accept. However, after Sophia falls ill, Stan comforts Dorothy which sparks old feelings in her and she contemplates trying to get back together with Stan.

After being dumped by her boyfriend, Blanche befriends a man at a bar and makes a date with him unknown to her he's blind. Meanwhile, Dorothy and Rose try their hand at coaching a kids' football team.

When Sophia sets Dorothy up on a blind date, Dorothy secretly falls for the seemingly simple man, claiming "he's the greatest lover she ever had." Meanwhile, Blanche and Rose join the "Be a Pal" and become pals to two motherless girls.

It's Valentine's Day, and the girls are all excited until each one of their dates cancel at the last minute. This leaves them to reminisce about Valentine's Day past.

Sophia goes into action to break her friend, Lillian out of ""the worst nursing home in the city."" However, Lillian proves to be too much of a handful for Sophia to handle. Meanwhile, Blanche considers having her breasts enlarged.

The girls participate in a murder mystery weekend and Dorothy has a ball when she solves a mystery. However, when Blanche is accused committing a real murder, Dorothy will have to use all her keen detective skills to find the real murderer.

Dorothy's old friend, Jean comes to Miami for a visit and Dorothy decides not to tell Blanche and Rose that Jean is a lesbian. Then, after spending time with Rose, Jean begins to fall for her. Meanwhile, a new VCR, prompts Sophia to rent ""dirty movies.""

The house is fumigated and the girls move into a Miami Beach hotel. Previously, Blanche had won three tickets to see the opening of Burt Reynolds new movie and passes to the party held afterwards where they could meet him. However, on the evening of the opening, the hotel is raided and, mistaken as prostitutes, Dorothy, Blanche and Rose are dragged off to jail.

The girls try to cough up enough money to pay for a new roof. Meanwhile, Sophia's volunteer job at the hospital is what brings the girls a piece of inside information that could give them enough money for a new roof and money left to spare. The info is that a famous artist is dying, so the girls head to an auction to bid on one of his paintings.

Rose is crazy about her latest boyfriend, Ernie, but can't understand why he doesn't approach the subject of sex, so when she forces the subject she learns the truth - he's impotent.

Dorothy's old friend, Trudy comes for a visit and this revives their old rivalry between each other. However, the visit turns tragic when Trudy suddenly dies and Dorothy blames herself.

After Sophia accidentally knocks a bottle of Rose's pills down the sink, it is discovered, she is addicted to them. She then must battle withdrawal when she can't get a hold of another bottle. Meanwhile, Dorothy and Sophia are hired to be in a pizza commercial.