Rose is shocked to learn that in her late-uncle's will he left her his ""Baby"". However she is quickly delighted to learn the ""baby"" is a pig but delighted is not a word to describe Dorothy, Blanche and Sophia, at least not until they learn that when Baby dies Rose gets a large sum of money.

When Rose must give a eulogy at her aunt's funeral, Rose must try to get over her biggest fear in the world, giving speeches. This also brings up Dorothy and Blanche's biggest fears, Dorothy's of flying and Blanche's of a recurring dream.

The girls try to help in a campaign to get Gil Kessler elected as local official. To his advantage, his chances of winning are boosted when reporters snap photos of Blanche entering his home one evening while his wife was away.

Dorothy is stunned to learn that Stan's tax problems are her tax problems since Stan is being audited for a number of years when they were still married. Meanwhile, Blanche and Rose take a Spanish class, each for different reasons.

Sophia announces her intentions of moving out and in with her son Phil. This prompts the girls to reminisce about the good times and the bad times they've had together.

As Sophia makes up her mind on whether or not to move in with her son, the girls continue to reminisce about the years they've shared together.

Sophia and Max come back from their honeymoon with no place to stay so Blanche, Dorothy and Rose put them up until they can find a place. Meanwhile, Sophia and Max decide to restart the old business Max had with Sophia's late husband, a pizza knish stand. However, Dorothy begins smoking again!

While Rose undergoes severe surgery, the girls try to entertain themselves with fond memories and laughter, only for Rose's daughter Kirsten to walk in on them enjoying themselves! Kirsten is spiteful of them and does not allow them to visit Rose. Kirsten visits Rose, who is near knocked out, and try to have a conversation...very comically as poor Rose is not altogether. With Rose going into surgery, Kirsten reconciles with the worried girls. At last, Rose is released and they all throw a surprise welcome home party for our lovable St. Olafian!

Blanche's uncle Lucas Hollingsworth is visiting but, to no surprise, Blanche is busy with a date. In order to be rid of his intrusion, Blanche tells Dorothy that he desperately wants to meet a woman of her intelligence. Dorothy agrees to see him but they both later learn that Blanche just lied to get rid of them and decide to get revenge by acting as though they're getting married, much to the dismay of Blanche. As a result, Rose decides she should move on to live with her daughter Kirsten to be the "Sophia of the household" as Blanche finally comes to terms with their idea to wed. Just as Lucas is about to reveal the truth, he decides to pop the question to Dorothy for real...

Dorothy accepts Lucas' proposal. The two plan to tie the knot two months later and on the way to the chapel, Dorothy takes a limo. However, this limo is driven by none other than Stanley Zbornak. The two share a rather comical but nonetheless touching moment together before arriving at the chapel. Down the aisle, along with Sophia, the girls think to themselves about the beautiful friendship they shared. Rose, Blanche and Sophia decide that the three of them should not depart and allow Dorothy on her way to Atlanta but she doesn't leave without sharing some final words with the girls...

Sophia befriends an old man on the boardwalk whom she becomes quick friends with. However, his strange behavior signals that he has a medical condition, Alzheimer's disease. Meanwhile, Blanche accidentally gives away Rose's teddy bear at a garage sale.

Rose is upset when she has missed her high school reunion due to being sick, so Blanche convinces her, Dorothy and Sophia to crash a reunion held in Miami, posing as absentees from that school. Dorothy goes as the lame prom queen Cindy Lou Peoples, Blanche is the seemingly slutty Susan, Rose is the Korean exchange student Kim FongToi and Sophia is Mrs. Gonzales. With that, the girls mingle with their "former" classmates, only to realize that their counterparts lives are as dull as theirs, however, when the girls are found out by the guests...Rose has a heart attack!

Sophia's latest get rich quick scheme prompts the girls to recall other various get rich quick schemes they've had over the years including, catering, a dance marathon and a memory of Sophia's from 1954.

The girls' search for a housekeeper ends when they hire Marguerite, a woman who appears to have mystical powers. However, when they fire her, a string of bizarre events convince the girls that Marguerite has placed a curse on them.

Blanche makes a move at Ted, Stan's brother the minute she learns he's a neurosurgeon. She is furious when she discovers the only woman Ted is apparently interested in is Dorothy. Meanwhile, Rose is suffering from insomnia.

Rose's cousin Sven, arrives in Miami for a visit just prior to him being married by arrangement. However, when Blanche plays a trick on her latest beau, which involves Sven, the naive groom falls for her. Meanwhile, Sophia tries to renew her driver's license.

Constant bickering, causes the girls to seek help from a therapist. This prompts the girls to reminisce about times they didn't get along. The therapist's conclusion, they should not live with one another.

Blanche is thrilled by a visit from her daughter, Rebecca, an ex-model who has now gained quite a bit of weight. Also visiting with Rebecca is her oafish beau who constantly puts down her weight. The kicker: she's thinking of marrying him.

Dorothy befriends a novelist, Barbara Thorndyke and she quickly infringes on Dorothy's relationship with Blanche and Rose who think Barbara is nothing but a stuck up snob.

Sophia got the girls a chance to appear on a hit game show Grab that Dough in California. At the hotel, they miss their reservations and they must sleep in the lobby...as a result, all their personal belongings are stolen. Sophia still has the tickets but once they arrive to the game, the girls fight and split into two separate competing teams.

Sophia's brother, Angelo, a priest, is coming to Miami for a visit and he doesn't know Dorothy and Stan are divorced. So in order to spare his feelings, Sophia convinces Dorothy and Stan to pretend to be married. Meanwhile, Rose and Blanche prepare to star in a play, The Sound of Music.

Sophia's latest boyfriend, Rocco claims to have been involved in the mob, so when the girls discover a bag of Rocco's with thousands of dollars in it, they assume he robbed a bank. Meanwhile, Dorothy and Blanche sneak a peak at Rose's diary.

Rose's latest boyfriend has just retired and she is ready to spend a whole lot more time with him but his retirement quickly turns him into a couch potato. Meanwhile, the girls deal with remodeling the garage into a guest room.

Dorothy's son, Michael pays another visit to Miami and this time he has an announcement, he's engaged. However, Dorothy has two more surprises in store, her future daughter-in-law is also black and twenty years older than Michael.

While waiting for phone calls from their children wishing them a happy Mother's day, the girls reminisce about past Mother's days.