Larry takes an unflinching look at the sexual assault allegations against Bill Cosby with panelists Jamilah Lemieux, Kathleen Madigan, Baratunde Thurston and Keith Robinson.

Larry takes a look at the controversy swirling around the movie "American Sniper" with panelists Matt Taibbi, Paul Rieckhoff, Sabrina Jalees and Nick Irving.

Panelists Common, Charles Blow, Joe Jones and Mike Yard join Larry for an in-depth discussion of African-American fatherhood.

Larry tackles viewers' questions about the anti-vaccine movement, obesity and beauty standards with Anthony Anderson, S.E. Cupp, Michaela Pereira and Rory Albanese.

Issa Rae, Christina Greer, Jacque Reid and Marina Franklin join Larry to discuss issues black women face in the workplace as well as the pros and cons of interracial dating.

Sunny Hostin, Phillip Agnew, Michael Skolnik and Godfrey discuss the disturbing findings from a Department of Justice's report on the Ferguson, MO, police department.

Bree Newsome recounts her mission to remove the Confederate flag in South Carolina, and Mike Yard, Holly Walker, Rory Albanese and Ricky Velez reach into Larry's Bag o' Grab.

Donald Trump calls out Sen. John McCain for being captured in Vietnam, and Larry examines the public's perception of Bill Cosby with Mike Yard, Kerry Coddett and Sunny Hostin.

Jon Stewart describes his rapport with President Obama, and Larry discusses the Lafayette, La., movie theater shooting with Brina Milikowsky, Penn Jillette and Ricky Velez.

Race barely gets mentioned during the GOP presidential debate, and Larry discusses Donald Trump's continued popularity with Yamaneika Saunders, Chris Gethard and Mike Yard.

Larry chats with "Welcome to Mars" author Buzz Aldrin and discusses America's response to the Syrian refugee crisis with Jordan Carlos, Natasha Rothwell and Billy Gardell.

Ben Carson rivals Donald Trump in GOP presidential polls, and Larry examines the arrest of Muslim high school student Ahmed Mohamed with Ice-T, Calise Hawkins and Ricky Velez.

Teen inventor Ahmed Mohamed pays a visit to The Nightly Show, and Larry examines the mass appeal of Pope Francis with Derek Waters, Naomi Klein and Mike Yard.

Ricky Velez interviews New Yorkers about Pope Francis, and Larry discusses disastrous selfies with Kerry Coddett, Will Forte and Andrew Rannells.

The CIA chief falls prey to hackers, and Larry discusses Joe Biden's announcement that he won't be running for president with Holly Walker, Ryan Duffy and Terry Crews.

Chicago Mayor Rahm Emanuel fires his police chief over the shooting death of a black teen, and Larry discusses colorblind casting with Spike Lee, Rory Albanese and Mike Yard.

An infamous pharma CEO is arrested on fraud charges, and Larry revisits some of the most significant stories of 2015 with Pusha T, Rory Albanese and Mike Yard.

Larry talks about the significance of the proposed Mars One expedition with Don Cheadle, Sonia Van Meter, Ricky Velez and Lee Daniels.

Larry discusses the backlash over the Oscar nominations' lack of diversity and the success of recent protests with Cory Booker, Talib Kweli, Bill Burr, and Shenaz Treasury.

Larry discusses the 2015 State of the Union address as well as the image and legacy of President Obama with panelists Jon Lovett, David Remnick, Amy Holmes, and Godfrey.

Larry discusses the changing state of U.S.-Cuba relations with panelists John Leguizamo, Soledad O'Brien, Mauricio Claver-Carone and Mike Yard.

Larry talks about the Disneyland measles epidemic and the fight against vaccines with panelists Holly Phillips, Judy Gold, Zoey O'Toole and Mike Yard.

Larry discusses the Koch brothers and the flood of private money in political campaigns with panelists Zephyr Teachout, David Webb, Hari Kondabolu and Ted Alexandro.

Larry tackles the Deflategate scandal and dishonesty in professional sports with panelists Jake Tapper, Katie Nolan, Sherrod Small and Seaton Smith.

Panelists Lance Bass, Sally Kohn, Jessica Kirson and Michel Faulkner join Larry to talk about America's growing acceptance of same-sex marriage.