A crisis arises when Ryan ignores Wilfred's advice.

Ryan forms a unique connection with his neighbor's dog after a failed suicide attempt.

Wilfred reveals an extraordinary ability when Ryan takes him to a hospice to volunteer.

Ryan has a guilt complex over the death of his childhood dog, and Wilfred, upon learning of it, goes to otherworldly lengths to help Ryan discover the truth about how the pooch passed on. Meanwhile, Kristen throws a party for her boss.

Wilfred is angry after Ryan tricks him into going to the veterinarian.

Ryan tries to reconcile with his sister, and Wilfred is in for a shock at doggy day care as a result.

Ryan and Wilfred make an extraordinary effort to boost Jenna's career.

Ryan must swallow his pride when Wilfred pursues a new love interest., and Ryan meets a new romantic interest himself

Ryan's resentment of his mother even grows when she moves in and becomes friends with Wilfred.

Ryan has to deal with new problems when Wilfred becomes popular.

Wilfred's nemesis returns with an offer that rocks Ryan's world.

Season 3 ends with Jenna forbidding Ryan from seeing Wilfred when he needs him most.

Wilfred tries to find Ryan a human friend.

Ryan meets someone who questions Ryan's friendship to Wilfred.

Just as Ryan finds happiness in his life, Wilfred begs him to sacrifice it for a larger purpose.

Ryan attempts to discover the truth about Wilfred through self-examination.

Wilfred muddles Ryan's plan to introduce Amanda to Jenna.

Ryan learns that life is much more challenging without Wilfred around.

When Wilfred comes to the conclusion Ryan is the only beneficiary of their friendship, he denies Ryan any further help.

Ryan is forced to intervene when Wilfred becomes embattled with an unlikely foe.

Unexpected problems arise for Ryan and Wilfred after a traumatic experience.

A spontaneous road trip proves disastrous for Wilfred and Ryan.

Ryan gets his wallet back (that's the good news) when his malevolent, porn-addicted neighbor Spencer shows up. The bad news? Spencer's looking for answers about who broke into his house. He's also looking for blood.

Wilfred leads Ryan on a crime-fighting caper.

Wilfred crashes Christmas and pits Ryan against his family.