Multiple stabbings, suicide attempts, a double shooting and an explosion at a flat flood the control centre of the London Ambulance Service with emergency calls threatening to overwhelm the service.

We join the staff in the nerve-centre control room on the night shift. Amongst the thousands of calls they receive, they also have to contend with hoaxers, frequent callers and run-away patients.

The staff of the London Ambulance Service prepare for another busy weekend. Amidst the call-outs to drunken fights, drug overdoses and stabbings there are also five women going into labour and a miscarriage to cope with.

A day shift takes an unexpected turn for West Midlands Ambulance Service paramedics, Nat and Nat, when a 999 call about an unconscious patient suddenly becomes very personal. In the meantime, a 19-year-old girl has been taken ill at school.

New Year's Eve is the busiest shift of the year for West Midlands Ambulance Service. Extra staff is brought in to care for those in need, but the night does not go as planned.

Pete and Matt, a specialist trauma team, are called to treat the victim of a brutal knife attack. Paramedics Christine and Chris start their day shift with a man who has collapsed in Worcester town centre after a suspected drug overdose. Jo and Tracey are called to 90-year-old Dennis, who's been vomiting. Christine and Chris are dispatched to Theresa, a terminally ill patient with suspected neutropenic sepsis caused by her cancer treatment. Crewmates Mark and Nieaal drive 20 minutes on blue lights to Ledbury in the dead of night to treat 96-year-old Jim.

Nina and Lauren respond to a caller whose mother has stopped breathing and is in cardiac arrest. The call handler in the control centre gives CPR advice over the phone while paramedics travel on blue lights to the scene.

At the start of a night shift, West Midlands Ambulance Service is receiving a High volume of emergency calls and is struggling to cope. A specialist paramedic attends a machete attack but his less urgent jobs are even more time-consuming.

The last Saturday before Christmas is a busy, with controller Sui having to prioritise stabbing victims and reports of drowning over patient's like Betty, whose daughter says she's fine but needs help getting up having fallen to the floor.

The North West Ambulance Service prepares for England's meeting with Croatia in the World Cup semi-final. As the country comes together in hope and excitement, the crews nervously anticipate the increase in calls that will follow no matter what the result.

While most enjoy a hot May bank holiday weekend in Manchester, North West Ambulance Service paramedics Gary and Claire need face matters of life and death.

Crewmates Dec and Nicole are urgently dispatched to a baby who has stopped breathing, and they also attend to a 12-year-old patient with a history of being bullied.

Multiple resources are dispatched to a patient who has fallen 20 feet from a tree and requires urgent treatment for a suspected broken back and open wrist fracture.

It’s a run of night shifts for the London Ambulance Service and delays are on the rise. Despite intensifying pressure, paramedic Rob uses his Essex charm to put every patient at ease.

In south west London, Martin attends a child hit by a car, while dispatchers Ed and Webster work tirelessly to get ambulances to patients as hospitals reach full capacity.

One of London's specialist mental health cars helps to ease pressure on the service from the growing number of patients in crisis, including a homeless university student living rough.

As London sleeps. crews battle to care for vulnerable, lonely and critically ill patients, including an elderly man who has suffered catastrophic trauma after a fall downstairs.

Aer a frantic 999 caller reports witnessing a relative being attacked by an XL bully dog, crews are dispatched – but the dangerous dog is still on the loose.

Crews respond to a patient in traumatic cardiac arrest after being stabbed. With his life hanging in the balance, doctors have no choice but to operate on him at the roadside.

Call handler Caelainn and her colleagues are sexually harassed by a persistent caller using a withheld number, which makes it hard to block his repeated calls.

A busy night shift for the ambulance service as they are alerted to an infectious disease outbreak at Fairfield General Hospital.

Crewmates Mandy and Lauren help an elderly patient at the local boatyard, who has been on the floor for two days before being discovered by his neighbour.

Filmed during a historical period of uncertainty for the NHS, this episode introduces the staff of North West Ambulance Service across Lancashire, from the picket line to the front line.

Justin and Dawn's first call of the day is to a woman whose waters have broken. A drunken man, repeat callers and a woman unable to leave her home all test the crews patience.

Crews in the more rural areas covered by the service are called out to an elderly couple, a train-spotter who has fallen and banged his head and suicidal patients.