Darrin forbids Samantha to attend her cousin Mario's wedding in Egypt. Endora, who is livid, states that Darrin is in "big trouble". Darrin gets a new assistant named Gideon Whitsett. Darrin is convinced Gideon is a warlock enlisted by Endora as a series of events makes Darrin look bumbling and stupid in front of a new client, and in turn makes Gideon look fantastic. Samantha uses a little magic to find out that Gideon is actually a conniving young man.

Samantha and Darrin spend the night at a hotel and Samantha briefly changes her hair to brunette. Larry spots them and thinks Darrin is having an affair. Larry proceeds to tell Louise. Louise meets with Darrin at a hotel hoping to convince him to drop the other woman. Larry spots them and thinks Darrin's other woman is Louise.

Samantha and Endora enjoy lunch at a great pizzaria owned by Mario. It seems that he is not selling pizzas and his business is going down the tubes. Samantha and Endora try to help out Mario, but ends up getting Darrin's job in danger.

As the final season begins, Samantha and Darrin take another vacation- all around Europe. Their vacation begins in the Tower of London where they are taking a tour. As they are touring, Samantha gets a call from one of the paintings- a nobleman on horseback. It seems that an evil witch had placed a curse on the nobleman, trapping him into a painting for a thousand years. The witch and the noble were destined to be married during Henry VIII's reign, forgetting that he was already married, the reason why he was placed in the painting. Being a nice person, Samantha lets him out. The moment he is released, the evil witch Malvina the Terrible appears. As punishment for breaking the curse, Malvina sends Samantha back to Henry VIII's time period. Once there, Samantha forgets who she is or why she is there. She comes across a group of instrument players and joins them in entertaining the infamous king, who falls for her. Darrin gets Endora to help him find Sam and save her with a kiss so she c

When Darrin begins searching for a beautiful model to play "Miss Jasmine", Endora sees it as an opportunity to break up her daughter's marriage and sends a gorgeous witch to seduce him. Samantha recognises model Janine Fleur as Sarah Baker the witch. Sarah is determined to fulfil what she set out to do, namely seduce Darrin despite Endora calling off the contract. Samantha, who still has faith in her husband, just wants her battle with Sarah to be on an even playing field.

Aunt Clara comes to visit when Samantha meets Darrin's parents or the first time, his mother, Phyllis feels pushed aside, but his father Frank likes Samantha, thinking she's a lovely girl. When her daughter-in-law serves a magnificent dinner, Samantha confesses that it was actually Aunt Clara who helped her with the food, and that she is still learning how to be a magnificent cook.

Samantha hires Zeno the Great to perform at a charity bazaar and becomes his assistant to help the magician gain self-confidence. When Roxie, Zeno's former assistant, returns to capitalise on his newly found fame, Samantha tries to stop the scene-stealing.

When an ankle injury confines Darrin to bed, Samantha enchants the house so it can fulfil Darrin's needs. Darrin becomes intoxicated with the idea of magic, and starts encouraging Samantha to use her powers, but the change is not all for the better. Darrin quits his job and wants to travel the world. But soon he comes to realise he likes his old life better.

Promising to behave when she meets Darrin's parents, Endora turns on the charm and is promptly accused by Darrin's mother Phyllis of trying to steal her husband Frank's affections. Frank takes Endora to a play when Phyllis refuses to go. Phyllis wants a divorce when Frank doesn't come home that night, but he actually locked himself out and stayed at the club. Endora and Samantha use a little witchcraft to get them together.

Knowing that Darrin needs a new model for a campaign, Samantha turns a stray Siamese cat into an attractive woman named Ling Ling. Ling-Ling, who knows she's a cat brings those cat sensibilities to her human life, Wally starts to fall in love with her. Ling-Ling likes the attention she is receiving from Wally and wants to stay human. Samantha has to figure out how to tell Darrin the truth about Ling-Ling while she and Darrin try to persuade Wally that Ling-Ling is not the right woman for him.

The mayor, ignoring his constituents' request to have a traffic light installed at a busy intersection, needs some of Samantha's witchcraft to convince him otherwise.

To assist her daughter in a dress fitting, Endora transforms herself into a double of Samantha. While at the fitting, Robert Frazer, a young writer, becomes smitten with her. Endora decides to cavort with him as Samantha. Meanwhile, Gladys Kravitz thinks Samantha is having a secret affair. There are further complications when it turns out that Bob is an old friend of Darrin's. Endora shows up as Samantha at a dinner that Darrin, Sam and Bob are having. Bob now believes Endora is Sam's twin.

After an argument while he is teaching her to drive, Darrin enrols Samantha in a driving school. The owner assigns his nervous brother-in-law Harold to teach her. Samantha gives Harold a little self confidence.

Samantha uses her powers to open her garage door as Gladys is watching from across the street. Darrin and Samantha buy an electric garage door to avoid further suspicions from Gladys, but unseen mortal technology causes additional problems and suspicions.

While Darrin spends time with neighbour Pleasure O'Reilly's sister, Dora "D.D." Danger O'Reilly, Endora arranges for handsome warlock George to woo Samantha to break up her marriage to Darrin. But when George arrives on the scene, he isn't sure if it's Samantha he wants or Danger.

Gladys and Abner have yet another fight, but this time, the frustrated busybody kicks her husband out of the house. Abner seeks shelter at the Stephens' home and quickly wears out his welcome. Sam decides to reunite the couple by having them simultaneously dream of the day Abner proposed.

Endora decides to experiment with different looks to Darrin's face while he is taking a nap. As Samantha forgets to change him back, a horrified Darrin sees the transformation they did to his face after he awakens. He becomes self-conscious about the way he looks. Samantha disguises herself as a sexy French sculptor to help repair her husband's tattered ego.

Endora tries to make peace with Darrin, but ends up shrinking him down to size . . . gradually. Samantha tries to get her mother to return Darrin to his regular size, but not before a drunk finds the diminutive Darrin in a mayonaise jar in the trash.

Because of Serena's foolishness, Samantha is sent back in time by a jelaous witch named Brunhilda, who happened to be Serena's boyfriend's wife. In 1868 New Orleans, Samantha is taken in by a maid named Aunt Jenny, and her owner, Rance Butler, falls for her. Now it is up to Darrin to get her back from the Southern gentleman.

Endora gets Tabitha to play beautifully on the piano, and Darrin dares Samantha to learn how to play the mortal way. The Piano teacher hears Tabitha play and invites a famous conducter to see her play. Without magic, Tabitha does a poor job and the conductor is stunned. Samantha then finds a real prodigy for the conductor, and wins the bet with Darrin.

Tabitha goes to pre-school for the first time and meets Amy, a classmate. When the teacher groups the children in animal groups, Amy gets chosen to be a toad in the toad group, but she wants to be in a butterfly group. Tabitha misunderstands her request and actually turns her into a butterfly! Samantha, who has been watching the whole thing through the window, chases Amy the butterfly all around the city and catches her so Tabitha can change her back.

Phyllis hires a maid for Samantha and Darrin, and a good-hearted maid named Amelia is chosen. The Stephens have to let her go because of the witchcraft in Samantha's family. Phyllis's friend, Mrs. Otis, decides to use Amelia.

Darrin learns that the truth does not always set you free when he is bewitched by a statue placed under Endora's spell that makes everyone tell the truth.

Darrin unknowingly gets three wishes from Endora. He blows the first two on fast elevators and bikini-clad girls, and he wishes that he was Larry for a day. He gets his wish and a whole lot of misunderstanding begins between Louise and the real Larry!

Because of a spell placed on a bowl of popcorn by Endora, Darrin becomes a great big couch potato. Samantha finds out what is going on when she finds Darrin, the milkman, and a TV repairman lazing around the messed up house. Samantha calls on Endora to take the spell off of them.