Recently married Darren Stephens receives a shock when he discovers that his bride is a witch. Samantha uses her powers to get back at Darrin's condescending ex-girlfriend Sheila.

When Samantha and Darrin purchase their first home together, Samantha and Endora use their magic to see what it would be like fully furnished. But their nosy neighbour Gladys Kravitz witnesses the acts of magic and becomes shocked and hysterical.

When Darrin's alcoholic and lecherous client Rex Barker makes a pass at Samantha, she decides to teach him a lesson by turning him into a dog. The dog runs away, but Samantha eventually gets him back. When Rex makes another pass at her, Darrin knocks him cold. Rex does wind up giving Darrin his account.

Samantha has lunch with a few of her nosy neighbours, using magic to assist with the meal. Endora refers to Darrin as "What's his name", and that night at their first meeting, Darrin tells Endora that they can get along without witchcraft. They have a heated exchange before Endora leaves.

Samantha suggests clever slogans for Darrin's Caldwell Soup advertising campaign. Darrin is thrilled until he suspects Samantha of using magic to help. A fight ensues and Samantha goes home to mother. Darrin relents and pitches Sam's slogans to Caldwell. He doesn't like them either. Darrin now realises Sam didn't use any magic.

To help a boy named Marshall Burns gain self-confidence, Samantha uses her magic to help him to become a star baseball player. After Darrin dissuades her from using further supernatural help, she instead tries to persuade the boy's overprotective mother to support him. Marshall does gain self-confidence and hits the game winning home run. His mother realises that she needs to let him do the things that little boys do.

Darrin's latest client wants to use a stereotypical ugly witch to promote his Halloween candy. Samantha is understandably upset, as are Bertha, Mary, and Aunt Clara, a trio of elderly witches who have dealt with prejudice for quite some time. When Darrin is fired for creating a campaign with a beautiful, curvaceous witch, the foursome teams up to give the client a taste of his own medicine.

Teenage reporter Liza Randall interviews Darrin for her school paper, arousing jealousy in her boyfriend Marvin "Monster" Grogan. When Samantha conjures up food to keep him distracted, Monster's appreciation for Samantha causes Liza to become jealous as well.

With her husband working overtime, Samantha is bored and agrees to have lunch in Paris with Endora. She happens to run into Larry and Louise Tate while there, creating confusion and hard feelings between Samantha and Darrin. After some missed connections, Samantha and Darrin fly to Paris together.

Maurice, Samantha's father learns she's married, and wants to meet his new son-in-law, but disapproves of mixed marriages, and an argument prompts him to disintegrate Darrin. Endora is furious, and Samantha tells Maurice she loves Darrin and not to take him away from her.

When Darrin begins searching for a beautiful model to play "Miss Jasmine", Endora sees it as an opportunity to break up her daughter's marriage and sends a gorgeous witch to seduce him. Samantha recognises model Janine Fleur as Sarah Baker the witch. Sarah is determined to fulfil what she set out to do, namely seduce Darrin despite Endora calling off the contract. Samantha, who still has faith in her husband, just wants her battle with Sarah to be on an even playing field.

Larry sees Louise and Samantha entering an obstetrician's office and assumes Darrin is about to become a father. It is actually Louise who is pregnant, but she is afraid to tell Larry. After Larry tells Darrin, he has a daydream about Samantha having "witch" children. When the four of them have dinner that night, the truth comes out.

Samantha asks Darrin to help her plain friend Gertrude find a beau. When a handsome artist, Kermit, is attracted to her, Darrin accuses Gertrude of being a witch. Samantha refuses to tell, leaving Darrin to try to break up the budding romance by calling on model Susan, Kermit’s ex-girlfriend.

Aunt Clara comes to visit when Samantha meets Darrin's parents or the first time, his mother, Phyllis feels pushed aside, but his father Frank likes Samantha, thinking she's a lovely girl. When her daughter-in-law serves a magnificent dinner, Samantha confesses that it was actually Aunt Clara who helped her with the food, and that she is still learning how to be a magnificent cook.

The Kravitzes and Stephens participate in a program that allows orphaned children to stay with adults for the holidays. When the Stephens' young charge reveals that he does not believe in Santa Claus, Samantha takes him to the North Pole.

Samantha hires Zeno the Great to perform at a charity bazaar and becomes his assistant to help the magician gain self-confidence. When Roxie, Zeno's former assistant, returns to capitalise on his newly found fame, Samantha tries to stop the scene-stealing.

When an ankle injury confines Darrin to bed, Samantha enchants the house so it can fulfil Darrin's needs. Darrin becomes intoxicated with the idea of magic, and starts encouraging Samantha to use her powers, but the change is not all for the better. Darrin quits his job and wants to travel the world. But soon he comes to realise he likes his old life better.

Accompanying a beautiful, sexy client to Chicago, Darrin begins to act strangely when he suspects that her cat is actually Samantha in disguise.

Promising to behave when she meets Darrin's parents, Endora turns on the charm and is promptly accused by Darrin's mother Phyllis of trying to steal her husband Frank's affections. Frank takes Endora to a play when Phyllis refuses to go. Phyllis wants a divorce when Frank doesn't come home that night, but he actually locked himself out and stayed at the club. Endora and Samantha use a little witchcraft to get them together.

Darrin forbids Samantha to attend her cousin Mario's wedding in Egypt. Endora, who is livid, states that Darrin is in "big trouble". Darrin gets a new assistant named Gideon Whitsett. Darrin is convinced Gideon is a warlock enlisted by Endora as a series of events makes Darrin look bumbling and stupid in front of a new client, and in turn makes Gideon look fantastic. Samantha uses a little magic to find out that Gideon is actually a conniving young man.

Knowing that Darrin needs a new model for a campaign, Samantha turns a stray Siamese cat into an attractive woman named Ling Ling. Ling-Ling, who knows she's a cat brings those cat sensibilities to her human life, Wally starts to fall in love with her. Ling-Ling likes the attention she is receiving from Wally and wants to stay human. Samantha has to figure out how to tell Darrin the truth about Ling-Ling while she and Darrin try to persuade Wally that Ling-Ling is not the right woman for him.

While Darrin, Samantha and Endora are browsing through an antiques store, Endora believes it's time Darrin suspected that Samantha may not be as young as her mortal equivalent would be. Darrin sees a 300-year-old painting, "Maid of Salem", which bears a striking resemblance to Samantha, causing him to question her age and their relationship. As Darrin contemplates his future with Samantha under these circumstances, Samantha has to figure out a way to save her marriage if the truth truly does comes to light.

The mayor, ignoring his constituents' request to have a traffic light installed at a busy intersection, needs some of Samantha's witchcraft to convince him otherwise.

To assist her daughter in a dress fitting, Endora transforms herself into a double of Samantha. While at the fitting, Robert Frazer, a young writer, becomes smitten with her. Endora decides to cavort with him as Samantha. Meanwhile, Gladys Kravitz thinks Samantha is having a secret affair. There are further complications when it turns out that Bob is an old friend of Darrin's. Endora shows up as Samantha at a dinner that Darrin, Sam and Bob are having. Bob now believes Endora is Sam's twin.

Flirtatious neighbour Pleasure O'Riley moves in next door to the Stephens. Samantha doesn't really appreciate Pleasure's ignorantly blissful helpless girl demeanour, or Darrin's seeming fawning over her at her beck and call because of it. Her incredibly jealous boyfriend, 'Thunderbolt' Swenson, mistakenly suspects both Darrin and Abner Kravitz of impropriety.