Serena returns for the last time and babysits with Tabitha and Adam. Larry comes by to return a golf club and Serena does an Abby Cunningham on him. Larry hurries off, but not before Serena gives him a pill to be young and active (pre-Viagra!). It makes him younger, all right, by ten years! Larry gets even younger and younger and everyone is very worried about him. Serena gives him an antidote which turns him back to normal.

Tabitha has to take a test to prove her intelligence and is very nervous. Endora helps her out by puuting a spell on her, making her a super genius! Miss Peabody, the teacher from episode 246, is amazed about Tabitha's knowledge and tells the principal about it. Samantha find out about this, and tells Endora to take the spell off Tabitha. Miss Peabody will not back off, and she catches Tabitha and Adam using their powers one day. Samantha catches Miss Peabody trying to be like Gladys Kravitz and gives her a lesson about snooping she will never forget.

Serena visits Samantha because she is stripped of her powers. She then falls for Darrin's newest client Harrison Wilcott and decides to go out with him. Samantha tries to tell Wilcott that Serena is bad news, but Wilcott has fallen for Serena. So Samantha finds Countess Pirhana (who took away Serena's powers) and makes Wilcott fall in love with the Countess.

As the final season begins, Samantha and Darrin take another vacation- all around Europe. Their vacation begins in the Tower of London where they are taking a tour. As they are touring, Samantha gets a call from one of the paintings- a nobleman on horseback. It seems that an evil witch had placed a curse on the nobleman, trapping him into a painting for a thousand years. The witch and the noble were destined to be married during Henry VIII's reign, forgetting that he was already married, the reason why he was placed in the painting. Being a nice person, Samantha lets him out. The moment he is released, the evil witch Malvina the Terrible appears. As punishment for breaking the curse, Malvina sends Samantha back to Henry VIII's time period. Once there, Samantha forgets who she is or why she is there. She comes across a group of instrument players and joins them in entertaining the infamous king, who falls for her. Darrin gets Endora to help him find Sam and save her with a kiss so she c

Darrin finds out that if Samantha marries Henry VIII, she will indeed be beheaded. Darrin tries to get Samantha away from Henry, but that proves to be very hard because she doesn't know who he is. Darrin gets thrown in the dungeon, but Endora saves him. At a party that Henry VIII is giving, Endora talks to Sam about giving up the king and going with Darrin. Henry VIII threatens to behead Darrin, but Endora suggests that they have a wrestling match. With Darrin in pain, Sam kisses him and gets back her memory. They all return home to the present, and Endora releases the nobleman for good.

Samantha has lost her powers again and it seems like Maurice's magic is gone as well when he visits her. Dr. Bombay discovers that no one should kiss Samantha or they would lose their powers. So, until his powers come back, Maurice lives like a mortal. Maurice then helps out Darrin by winning a chili account for him. And that's when Samantha and Maurice get their powers back respectively.

The Stephens are sightseeing in Rome, and Endora tries to test Darrin's loyalty by bringing the famous Venus statue to life. When Darrin meets her (now named Vanessa), he misses an important meeting with a client named Mr. Baldoni, who also falls for Vanessa. Samantha, deciding that this is just too much, takes it upon herself to bring the famous Adonis statue to life. Adonis and Vanessa meet and fall in love instantly and are zapped back to the museum in their original forms- but with a small difference: they hold hands!

Hansel and Gretel are brought to life by Tabitha and are very sad and hungry. Tabitha decides that they should spend the night and goes into the storybook to ask their father. Samantha finds out and goes in the book after her, leaving a confused Darrin and the Tates at the dinner table. Worse of all, Hansel and Gretel run away again to look for food in the real world. In the storybook world, Sam finds Tabitha locked in the wicked witch's house. She brings Tabitha home and after a whole lot of confusion and police involvement, Hansel and Gretel are sent back into the storybook. Now, to get out of the situation of putting on a play of ""Hansel and Gretel"".....

Endora tries to make Samantha jealous again by recruiting a beautiful, sexy witch named Ophelia on Darrin. Ophelia tries anything to get Darrin to come to a sales convention, even fake stage fright. Darrin intentions are to spend time with Samantha, but Larry Tate intervenes. Darrin goes but decides to take a late plane back, but the unrelenting Ophelia disguises herself as an airport manager, informing Darrin the airport is closed due to fog. Endora suggests to Samantha that fog is not the reason Darrin is not coming home. Sam realizes that there is something fishy going on pops in to see what is up. With a little magic, Darrin realizes that Sam is his real love and Endora's in the hot seat.

In the final episode, Endora tries to test out Darrin's honesty by giving him a pin with a spell that makes him tell the truth. Darrin learns that honesty is not exactly the best policy when he jeopardizes an important account. It seems as though he may have lost the account, but the client likes the honesty between Darrin and Larry and gives them a break. As the series ends, Samantha and Darrin tell each other how much they love each other, without the magic of the truth pin.

Endora's causing trouble again! This time, instead of breaking up a marriage, she's breaking up Darrin's advertising company. She calls up Alonzo, a warlock who casts a spell on Larry, making him like all of his ideas on a carpet account instead of Darrin's. It gets to a point that Darrin quits McMann and Tate, but finds out that this is all Endora's fault. To get even with her, Samantha magically sets up an advertising campaign to handle the carpet account.

The European vacation is over when Darrin and Samantha pack up and are about to head home. Their departure is disrupted when Larry and Louise invites them to spend a weekend at the Duke of Whitset's hotel castle. It turns out that this hotel is hanuted by a ghost named Henry, who happens to be the Duke's ancestor. Harry is turned on by Samantha, and to get a little bit close to her, he possesses Darrin's body. When Harry (in Darrin's body) is shut down by Sam, he moves on to Louise! Samantha calls up a lady ghost to ward Harry off. Darrin gets his body back when Harry leaves it to be with the lady ghost. Now we can call it a day in Europe as the cast heads for home.

In this crazy episode, Samantha gets a condition which makes her entirely 500 pounds heavier. Dr. Bombay comes and gives her an antidote that makes her lighter...a little too light as she floats to the air! This will be hard to hide when the Prescotts, McMann and Tate's newest clients, has Samantha volunteer for a charity bazaar and fashion show. Sam tries everything to help weigh her down, but to no avail. In a memorable scene, Samantha holds a giant urn on her shoulder as she goes down the runway half floating, half walking in the fashion show. It is there that Darrin comes up with a spectacular slogan for Prescott shoes.

Tabitha wants to learn how to skate, and Samantha agrees to take lessons with her in the mortal way. When Tabitha falls down constantly, Endora cannot take much more and decides to bewitch Tabitha's skates so that Tabitha becomes a terrific skater. Tabitha is bound to be the next Tara Lipinksi if Endora doesn't take that spell off of her. So Endora does and Tabitha is back to being a poor skater again.

Tabitha is working on a project on George Washington for school, and needs help. Esmerelda helps out, but accidentally conjures the real George Washington! Samantha tries to keep an eye on George, but he wanders off into the park where he is caught by a policeman. The policeman lets George go on a $2000 bail. As soon as Sam and Darrin bring George home, Esmerelda remembers the spell and sends George back, without his shoes! Esmerelda brings him back, but this time, he is joined by Martha Washington....

The Washingtons adjust to life in the twentieth century as they stay with the Stephens. Larry sees them both and decides that it is a great ad campaign for his new clients, the Whirlaway Washing Machine Company. George cannot tell a lie about the washer and, as a result, loses the account for Larry and Darrin. He does the same thing in the courtroom and his charges are dismissed. Then the Washingtons are finally send back to their own time.

"I know that Tabitha is ready for school, but is school ready for Tabitha?" warns Sam. Tabitha attends school for the first time, and has a pretty hard time because a boy is messing with her. When he refuses to give up, Tabitha turns him into a frog. The teacher Miss Peabody gets on her about the frog and tells her to put it back in the class terrarium. Tabitha grabs the wrong frog and Samantha pops into the school and changes the frogs. When the right frog is brought home, Tabitha changes it back before the boy's mother finds out.

The Witches Council wants to test out Adam to see if he is a warlock or a mortal. If he is a mortal, he wilh have to be taken away from the Stephens' household. Maurice helps Adam by giving him powers so that he will not be taken away. Adam is indeed normal, but he does have his own powers tucked away somewhere.

Esmerelda's magic seems to be all wrong and is a failure as a witch. Larry says that a client of his needs a babysitter for the evening and gets Esmerelda to do the job so he can sign the contracts to win the deal. Esmerelda shows the Norton's child, Ralph, some magic and No one believes him when he tells all about it. As a result, Esmerelda is fired and Larry loses the Norton account. So Samantha sets up a dinner party with Esmerelda as a magician. Once everything is cleared up, everyone gets what they wants: The Nortons are friends again and Larry wins the account.

Endora transforms Darrin into a gambler. Samantha inisists Endora remove the spell. Endora makes more trouble by having Darrin bet on a horse named Fancy Dancer that is bound to lose, and Darrin gets Larry and a client to place all bets on Fancy Dancer. Samantha pops to the stables to talk to Dancer about winning the race for her husband and his friends. In the race, it seems like Dancer is bound to come in last, but he pulls through and wins!

Tabitha speaks out about violence on TV. She pops on a TV show to reprimand two aggressive puppets. Of course, Darrin happens to be watching the show and tells Sam to get Tabitha off the TV. The sponsors say otherwise and Tabitha becomes a TV star. The Stephens are dead set against this and Sam makes sure that the sponsor, Mr. Silverton, brings his own daughter to the show for back-up. Tabitha isn't quite ready for the home audience yet (until 1977 with her self-titled spin-off show) and Robin, the Silverton's daughter wins her chance to be in the spotlight.

Next Stop, Italy! The Stephens enjoy their vacation in a hotel overlooking the famous Leaning Tower of Pisa. Of course, Esmerelda pops in due to a lack of confidence. Esmerelda reveals that she made the tower lean by mistake when she was engaged to the builder. So Esmerelda takes it upon herself to right the wrong...by actually straightening the Leaning Tower of Pisa! The town totally freaks out when the famous tower is straightened correctly, and Esmerelda cannot remember what happened to make the Tower lean in the first place! A trip back in time helps her to remember. It seems that she tried to twitch up a tower sandwich for the builder and to make it lean, thus making the Tower lean again.

Samantha and Darrin are now in lovely Paree and Endora is home with Tabitha and Adam. Maurice comes by the house and finds out that the Stephens are vacationing in Europe. He is mad because they should have stopped by in London to see how he was doing. Endora flies to Paris to warn Samantha and then Maurice appears in a scary cloud of smoke. Out of rare kindness, Endora zaps up a fake Darrin who charms and pleases Maurice. Everything just seems all right until the real Darrin comes in. Maurice notices the trick and sends poor Darrin to the top of the Eiffel Tower. Unbeknownst to him, his very appearance there makes a perfect advertising campaign for one of his clients who runs a travel agency.

Sam and Darrin have dinner at a chinese restaurant and Sam orders a drink called ""The Heavenly Himalayan"" which causes her to lose her powers and to break out with stripes on her face! Dr. Bombay tells her about an antidote and Sam gets it from an Apothecary, only to break out with more stripes on her face. Dr. Bombay then tells her that she needs a feather from a Dodo bird, but then that doesn't work either. There is another important ingredient needed: a piece of Himalayan cinnamon stick from the Chinese restaurant. After Darrin gets in trouble for getting the cinnamon, he gets it for Samantha and she is cured again.

Sam and Darrin visit Inverness, Scotland, the place famous for the Loch Ness and its legendary monster. It seems that the monster is actually a warlock named Bruce who was transformed by Serena. To save Bruce's life, Sam calls on Serena to get him out of the spell. Once transformed, Bruce decides to get even with Serena by giving her a mermaid's tail! The reporters go crazy about the Loch Ness Monster, and Bruce wants to be a monster again. So he changes Serena back and Serena returns the favor by sending him back to the way he used to be, but with a little understanding about how important he really is.