A sick lady with a monkey provides the key to a mysterious, highly contagious, and deadly virus that strikes both Dr. Brackett and John. Meanwhile, the firemen rescue a boy from a treehouse and a man from a scaffold.

Roy and John rescue a man whose engine has fallen on him during his car repair work. When their two-way radio is broken, Roy treats the man without proper medical supervision, causing the man's doctor to attack the paramedic program. Also: a bull gores a motorcyclist, a doctor on a consult at the hospital dies of a heart attack, Roy rescues a child from a house fire.

Dixie injures her toe. John decides he can make a lot of money by riding in rodeos. The squad goes to a hole-in-the-wall restaurant when a soda bottle explodes in a girl's face; later, they return for a gas explosion. After falling from a tree, a young boy lapses into a coma. The firemen rescue several children and a nun from a bus crash.

A drunk driver rams a parked car, trapping a child inside. Chet pesters John about his Native American heritage. A kid gets his finger stuck in a gumball machine. A woman's new girdle causes breathing difficulties. A worker's error leads to fuel being mixed with the water supply, causing explosive results. A sniper makes a scaffold rescue dangerous.

A former Vietnam medic is now a paramedic trainee and constantly thinks he knows more than the doctors at Rampart. Roy, John, and the trainee interrupt a purse-snatching, rescue a man who fell down a cliff, help a woman overdosed on prescription drugs, and save a man with an insulin reaction.

A photo shoot at the station gets John excited. A country doctor helps Roy and John when they can't reach Rampart on a call. The paramedics rescue a man drowning in a swimming pool and two stuntmen trapped on a waterfall at a movie studio.

John falls for a lady deputy when called to treat a mugger. Items are stolen from Rampart. The firemen rescue an elderly man from a house fire. Boot returns to Station 51. A grandfather is injured by a model rocket. The paramedics rescue a boat thief trapped on a crane.

After Chet cracks a joke about John playing the Squad horn, John takes up the bagpipes, trombone, and guitar. Paramedics help a gardener suffering from tetanus. The father of a boy suffering from lead poisoning is reluctant to have it treated. The firemen rescue the driver of an ice cream truck. A schoolgirl dies from an overdose. A glider pilot crash lands. A man working under his house is trapped.

John tries to convince Roy he has tonsillitis. An old flame of Dixie's, who is now a famous actor, is admitted to Rampart. Two kids are trapped on top of a gas tank; a girl's college lacrosse game turns violent; Boot has surgery to remove a tick; Dr. Early deals with a hypochondriac. Chet is injured during a rescue and is roomed with Roy, who has had his tonsils removed.

The firemen are puzzled by Boot's strange behavior. Meanwhile, paramedics rescue a woman whose sports car is pinned under a gas truck and investigate a series of unusual incidents in the home of a woman attempting to cook a meal for her boyfriend and his mother. An unconscious man is brought in to the hospital suffering from internal bleeding. Dr. Early deals with the victim of a curse. An explosion in a hospital lab endangers a number of workers and important records.

Roy and John are accused of stealing money from a victim. A premature delivery and a blinded man result from a car crash. A perilous rescue involves a plane that might explode.

The station adopts a stray dog, which they name Boot. The firemen rescue a boy from a hole; he turns out to be an abused child. Roy and John rescue another boy whose head is stuck in a basement window. Dr. Early extracts a child's arm from a steering wheel. At a brush fire, Boot helps locate an injured hiker, then leaves with a hook and ladder truck.

A woman almost hits a kid on a bike, who starts choking; she later has an epileptic fit. A man is shot by his father-in-law when he learns his daughter is married and pregnant. Roy tries to set John up with his wife's cousin. Three drug addicts are treated in the hospital: a woman with a gangrenous hand, a poison victim and a man showing signs of tetanus. In the field: an alcoholic, an obese man with a pacemaker, and a child whose arm is caught in a swimming pool drain.

A new trainee appears to be lacking in confidence; a bookcase falls on an elderly gentleman searching for a book; a baseball player is injured; an ambulance is hit by a car; a boy's chemistry set explodes in his face; students play a practical joke on a sleeping man; a man is injured at a junkyard.

A gas explosion results from a white lie, prompting Johnny to go on an honesty kick. At the hospital, doctors work to save a boy who is inexplicably choking to death. In the field, the paramedics rescue a teenage boy injured in a dive off a roof, and a baby and his blind grandfather trapped in a burning house.

Roy has an argument with his wife and Johnny tries to help. The firemen rescue a man from precarious auto wreck. A brilliant doctor's erratic behavior causes concern at the hospital. Doctors diagnose a woman's heart condition. Paramedics rescue a dog from a roof and two children lost in a rapidly flooding storm drain.

John gets bugged by other people's bad driving habits. A college quarterback experiences back pain. Roy and John's former paramedic instructor dies, while Roy and John themselves teach a CPR class. A boy gets stuck inside a tree. A structure fire at a hotel is complicated by a cardiac victim on the third floor.

John is audited by the IRS. A man hit on the head wants to be treated by a doctor, not the paramedics. A child is rescued from a locked car. A pregnant girl has difficulty breathing. A professional medical con man shows up at Rampart. A construction worker is trapped when part of the building his crew is working on collapses, and he wants Roy to remove his leg before the rest of the building falls.

A woman journalist covers the Squad's rescues. A man trapped is in a truck under live power lines. Doctors treat a boy poisoned by wild hemlock and a girl addicted to drugs. The paramedics rescue a man trapped in a sofabed, a man wihose arm is stuck in a garbage disposal, and a man trapped in a bombed building.

A man shows signs of schizophrenia for no apparent reason and the Secret Service won't give any clues. Roy has an admirer, yet John accuses him of having no charisma. The paramedics respond to a false alarm on a fireboat, and end up saving the victim of a plane crash; they also deliver a premature baby and rescue a man threatening to jump off a tall building.

A woman keeps calling the Squad because she's convinced the bad things that happen to her husband are the result of her recently deceased sister. A youth suffering side effects from tranquilizers is treated in the ER. The paramedics rescue a man pinned under a stack of heavy cartons and a driver trapped underwater in his car.