Mace Gore's gang has taken over Dodge. When Matt is believed killed, Festus and Doc have a plan to lure Gore into a trap, even though his usual plan is to leave by dawn.

Festus has a habit of using the wishbone from a dead chicken for making wishes on. When he comes across Doc Adams, alone and snakebit, he uses that wish to help him, if it can. Meanwhile, Matt searches for three outlaws who held up a stage, killing the driver and guard.

A band of robbers have hit numerous banks with uncanny precision, planning and ease. They have their sights on Dodge now but they must remove a big obstacle before they can proceed - Marshal Dillon.

When one of the gang is hurt after robbing Dodge, the Doc is taken to patch him up. The posse was preparing to go after them but a new problem has been set they must take care of before they can recover their friend.

Someone has placed a fabulous price on Matt's head, and there are many competing to earn it.

Lured out of retirement with the promise of land, a bounty hunter is aimed by his boss at the man who killed his son; however, he neglects to tell his hound that the reward and charges had been dropped.

When old Jacob is shot dead in self defense, his loyal Indian partner, John Walking Fox, starts paying for things with $50 gold pieces, and he becomes the talk of the town, and a target for would be robbers.

Fast gunman Jim Barrett kills a man in self defense. Now the man's father and brothers are gunning for him, in addition to a young man who wants Barrett dead for a different reason.

In Matt's absence, Festus is accused of drawing first on a drunken man. Though innocent, Festus leaves town to avoid Matt having to arrest him, and takes refuge across the border with a widow and her son.

A mysterious man rides into town and says he is after one of two men responsible for killing his brother. When he starts crowding a stranger in town, Matt must decide how to make sure he doesn't take the law into his own hands.

A retired judge and his sons abduct Kitty, Festus, and Doc after Festus shoots his other son in order to defend Kitty. The judge "tries" Kitty and Festus for murder, pressing Doc into service as their defense attorney.

Kyle Stoner is fast with a gun and likes to prove it. When he mixes with the wrong crowd and goes up against Matt, his father gets involved and he is a friend as well as an ex-lawman.

A man is convicted of robbing and murdering his partner, but the sons of Matt's old friend are responsible. Matt must arrest the remaining son after the other's dying declaration and make it to Hays City in time to stop the hanging.

A twelve-year-old boy recovers in Doc's office and then goes with a gun after the man who robbed and killed his father.

Twenty-two men escape from a territorial prison. The remaining 4 kidnap Matt hoping to get safe passage into Mexico. One of them has another agenda which he reveals to Matt as they get closer to the border.

After a risky train robbery and with two posses on their trail, four men hurriedly ride to some fresh horses. Dillon wounds one of the gang carrying the stolen money and it turns out to be a young woman.

Buffalo hunters kidnap Doc and Festus. Guest starring R.G. Armstrong, George Lindsey, Gregg Palmer, and Shelley Morrison (Trivia: directed by James Arness' kid brother Peter Graves just prior to his finding fame as Jim Phelps on Mission: Impossible.)

Thad, son of and deputy to an Oklahoma sheriff, arrives in Dodge pursuing vandals on his father's warrant, not realizing the Oklahoma warrant isn't executable in Dodge.

A man who persuaded the good folks of Dodge to invest their money in a mine is out of prison and back to prove that there really is gold in the mine.

Two Bounty hunters bring in a wounded Mexican bandit worth $30,000 and find out the Mexican government might not pay for a man who dies a natural death, so they get the idea of shooting him dead.

A young Pawnee arrives in Dodge to seek his own revenge on a murderer, not trusting in the white man's justice.

An elder brother took the blame for the younger as both were sent away for cattle rustling. When they return home, the younger is not done with doing wrong, nor with asking his brother to cover his tracks.

Billy has always looked up to his brother Ed. During a robbery gone wrong, he is arrested. Matt begins to open Billy's naive eyes when his brother tries to free him from jail.

Some homesteaders have chosen a piece of land that is free to use per the government, but Ben Payson has other ideas. When his daughter starts to care about the homesteaders' son, Ben decides to force them off the property regardless the cost.

After a successful search for gold, two prospectors hire a man, who shows up at their campfire, as a bodyguard.