Oren was a rancher who liked his drink, gambling and women, even though he had a pretty wife at home. Matt is forced to kill him and when he breaks the news to her, all she can see is getting revenge for his death, and Matt is her target.

Billy Poe is falsely accused of murder by a dying man, and flees to another town while Matt follows him, and encounters dangerous resistance from other men who hate lawmen.

Two men want to rob the bank in Dodge, but are unwilling to try it while Matt lives. A man agrees to accept the job of killing the marshal, attaching some rather peculiar conditions to his acceptance.

A retired lawman and showman wants only to settle down with the Dodge seamstress he left behind twenty years ago, but a young whippersnapper hopes to make a name for himself by challenging the aging gun to a duel.

Mace Gore's gang has taken over Dodge. When Matt is believed killed, Festus and Doc have a plan to lure Gore into a trap, even though his usual plan is to leave by dawn.

An outlaw gang shoots it out fleeing Dodge City. When one of them is injured real bad, he hides out in the church where the reverend is fearful but not for himself.

Doc Adams takes up arms to defend a gold shipment from bandits, first during a stagecoach ambush and then at a weigh station. He is aided by a blind man and a wounded man in the battle against the bandits.

A comedic episode. Two hillbillies attempt to turn their 102 year-old relative in for the bounty on him.

Chester is embarrassed at a visit by his estranged mountain man brother Magnus. To prove that Magnus is too uncivilized for town, Chester tours him through the highlights of Dodge: card gambling, drinking, and talking with Kitty. Meanwhile, the Long Branch women plan a Christmas Eve dance which is busted by the spiteful Lucifer Jones.

Johnny Cole kills a crooked card dealer in self defense, and then falls in love with the dealer's beautiful daughter, but she resists his advances and wants to seriously hurt him instead.

Chester is smitten with Polly, but she has eyes only for Wade, a man new in town and newly her father's employee. Knowing little about Wade, Polly agrees quickly to marry him, but Chester discovers that Wade already has a wife.

An old rancher returns home after many years in prison, ready to reclaim what is his by any means necessary, including burning out the squatters on his land.

Deputy District Attorney Shephard will do anything to further his career, including having outlaw John Farron killed, instead of being able to give himself up.

Fleeing from both Matt Dillon and his double-crossed partners, outlaw Gristy Calhoun discovers that his survival in the badlands depends on an Indian woman.

A father's dying request is that Matt go to retrieve his daughter. Expecting to find a little girl, Matt finds a near-grown woman, but one who's wild and desperately in need of civilizing.

Chester is sweet on a widow dressmaker. When the widow is not only intent on marriage but eager to make changes in Chester as well, he has second thoughts--especially after a talk with her child suggests that the widow may still be a wife.

Matt intercedes on behalf of ex-con Cope Borden, when Rance Bradley accuses Cope of horse theft and attempts to lynch him. Cope is proven innocent of the charge, but later kills Bradley's nephew in a fair fight during a gambling dispute. Matt is caught in an awkward situation when he must defend the unsavory Cope against the decent people of Dodge.

Hank Worth, son of wealthy rancher Jake Worth, is kidnapped by three men and held for $20,000 ransom. They shoot him in the back for trying to escape. They call on Doc but Hank dies. The killers decide to let Doc go because he is the only doctor within 400 miles and they fear they might need his services someday. Before sparing his life and freeing him, they force the reluctant Doc to give his word of honor that he will never reveal their identities.

When returning to Dodge, Chester and Matt are confronted by Holly Hawtree, whose father is desperately ill with gangrene. His only hope for survival is amputation of the affected leg. Matt performs the surgery, but the gangrene has spread too far and the old man dies. Matt later discovers that the presumed accident leading to Mr. Hawtree's condition was actually caused by Ben Walling, who has his sights on Holly.

Two outlaws seek the rumored hidden fortune of old prospector Obie. They drag him to get him to tell. Obie forgets his cares and disappears on honeymoon with newcomer Ella May. Matt suspiciously questions the simple Obie about Ella May's motives and finds Obie is deeper than he seems.

Clay Young is trying to evict Josh Nolan, who says he paid for the property. Matt and Chester are tied up in reluctantly enforcing eviction law unless they can find another way.

Buffalo hunter Jase Murdock is warned by storekeeper Ross to stay out of Indian territory. Matt talks with Murdock's skinner, Golden Calf, who determines that Murdock's medicine is no longer good.

Lucy professes her love for handsome Booth Rider, and concocts a scheme against Ephram. Booth becomes the unwitting pawn in a homicide that culminates in an ironic twist of fate.

Ex-con Perce McCall helps to save Matt's life in a shootout, and then falls for a beautiful, but greedy saloon girl who puts him under great pressure to start stealing again.

A headstrong young woman will undertake the long, dangerous journey to her fiancé's fort on her own if she must, so Matt nominates himself to escort her.