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The Best Episodes of Hamilton's Pharmacopeia

Every episode of Hamilton's Pharmacopeia ranked from best to worst. Let's dive into the Best Episodes of Hamilton's Pharmacopeia!

Binge this in 14h 40m•Peaking at 9.2/10

Join an incredible journey through the history, chemistry and societal impacts of the world’s most extraordinary drugs.

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Episode Rankings

  1. #1 Fan Favorite
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    Hamilton's Pharmacopeia Season 3 Episode 1 - Synthetic Toad Venom Machine
    9.2/10(47 votes)

    #1 - Synthetic Toad Venom Machine

    S3:E1

    Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

    Director:Unknown
    Writer:Unknown

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  2. Hamilton's Pharmacopeia Season 2 Episode 1 - The Psychedelic Toad
    9.1/10(83 votes)

    #2 - The Psychedelic Toad

    S2:E1

    Hamilton embarks on a quest to answer the most important question in ethnoherpetological history and along the way, he finds the power of love.

    Director:Unknown
    Writer:Unknown

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  3. Hamilton's Pharmacopeia Season 1 Episode 6 - The Lazy Lizard School of Hedonism
    9.0/10(65 votes)

    #3 - The Lazy Lizard School of Hedonism

    S1:E6

    We meet with famed LSD chemist Casey Hardison in the Nevada desert and embark on a roadtrip to visit the unsung hero of psychedelic history.

    Director:Unknown
    Writer:Unknown

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  4. Hamilton's Pharmacopeia Season 2 Episode 6 - A Clandestine Chemist's Tale
    9.0/10(60 votes)

    #4 - A Clandestine Chemist's Tale

    S2:E6

    Hamilton meets an unsung hero of the psychedelic underground and hears a tragic tale of MDMA synthesis and chemiluminescence.

    Director:Unknown
    Writer:Unknown

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  5. Hamilton's Pharmacopeia Season 1 Episode 3 - Shepherdess: The Story of Salvia Divinorium
    8.9/10(67 votes)

    #5 - Shepherdess: The Story of Salvia Divinorium

    S1:E3

    From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

    Director:Unknown
    Writer:Unknown

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  6. Hamilton's Pharmacopeia Season 2 Episode 4 - Wizards of DMT
    8.9/10(65 votes)

    #6 - Wizards of DMT

    S2:E4

    Hamilton travels across North America to study how and why DMT exists in the environment and the laboratory.

    Director:Unknown
    Writer:Unknown

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    7. Trending NowTRENDING NOW

    The 20 WORST Episodes of Hamilton's Pharmacopeia

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  7. Hamilton's Pharmacopeia Season 1 Episode 1 - The Story of the South African Quaalude
    8.8/10(73 votes)

    #7 - The Story of the South African Quaalude

    S1:E1

    South Africa is the last place on earth Quaaludes can still be found; Hamilton travels there to study the drug and learns of a dark history of medical experimentation.

    Director:Unknown
    Writer:Unknown

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  8. Hamilton's Pharmacopeia Season 2 Episode 2 - Peyote: The Divine Messenger
    8.8/10(59 votes)

    #8 - Peyote: The Divine Messenger

    S2:E2

    From the greenhouses of Thai cactophiles to the Tamaulipan thornscrub, Hamilton traces the history of peyote with the help of a Native American peyotist.

    Director:Unknown
    Writer:Unknown

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  9. Hamilton's Pharmacopeia Season 2 Episode 7 - A Fungal Fairy Tale
    8.8/10(49 votes)

    #9 - A Fungal Fairy Tale

    S2:E7

    Hamilton ascends the Carpathian Mountains, microscope in hand, to learn how Europeans use Amanita muscaria, and uncovers the chemistry behind a mushroom-inspired pharmaceutical.

    Director:Unknown
    Writer:Unknown

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  10. Hamilton's Pharmacopeia Season 2 Episode 5 - Ketamine: Realms and Realities
    8.7/10(65 votes)

    #10 - Ketamine: Realms and Realities

    S2:E5

    Hamilton heads to India to see industrial Ketamine synthesis, and speak with therapists and luminaries in an attempt to understand the role of dissociative anesthetics in society.

    Director:Unknown
    Writer:Unknown

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  11. Hamilton's Pharmacopeia Season 1 Episode 2 - A Positive PCP Story
    8.6/10(60 votes)

    #11 - A Positive PCP Story

    S1:E2

    Hamilton investigates the history of PCP in the U.S., seeking input from addicts, dealers and chemists.

    Director:Unknown
    Writer:Unknown

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  12. Hamilton's Pharmacopeia Season 1 Episode 4 - Magic Mushrooms in Mexico
    8.6/10(61 votes)

    #12 - Magic Mushrooms in Mexico

    S1:E4

    Hamilton explores magic mushrooms with the help of shamans, clandestine growers, and ethnomycologists.

    Director:Unknown
    Writer:Unknown

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  13. Hamilton's Pharmacopeia Season 2 Episode 8 - The Cactus Apprentice
    8.6/10(41 votes)

    #13 - The Cactus Apprentice

    S2:E8

    Deep in the Andean highlands of Peru, Hamilton becomes the apprentice of a local shaman, learning how to use the night-blooming San Pedro cactus as a medicine.

    Director:Unknown
    Writer:Unknown

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  14. Hamilton's Pharmacopeia Season 3 Episode 2 - A Positive Methamphetamine Story
    8.5/10(31 votes)

    #14 - A Positive Methamphetamine Story

    S3:E2

    From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs in order to understand the process behind a great American folk art.

    Director:Unknown
    Writer:Unknown

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  15. Hamilton's Pharmacopeia Season 3 Episode 6 - Ultra LSD
    8.5/10(28 votes)

    #15 - Ultra LSD

    S3:E6

    With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

    Director:Unknown
    Writer:Unknown

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  16. Hamilton's Pharmacopeia Season 2 Episode 3 - Kratom: The Forbidden Leaf
    8.4/10(53 votes)

    #16 - Kratom: The Forbidden Leaf

    S2:E3

    Hamilton investigates the pharmacology and traditional uses of Kratom, a Thai tree with opioid-containing leaves.

    Director:Unknown
    Writer:Unknown

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  17. Hamilton's Pharmacopeia Season 3 Episode 3 - Xenon: the Perfect Anesthetic?
    8.2/10(27 votes)

    #17 - Xenon: the Perfect Anesthetic?

    S3:E3

    Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

    Director:Unknown
    Writer:Unknown

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  18. Hamilton's Pharmacopeia Season 3 Episode 4 - Synethetic Ibogaine-Natural Tramadol
    8.0/10(27 votes)

    #18 - Synethetic Ibogaine-Natural Tramadol

    S3:E4

    After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

    Director:Unknown
    Writer:Unknown

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  19. Hamilton's Pharmacopeia Season 1 Episode 5 - Fish N' Trips
    7.8/10(45 votes)

    #19 - Fish N' Trips

    S1:E5

    Hamilton embarks on an aquatic adventure to Reunion Island and Madagascar to investigate ichthyoallyeinotoxism and a twisted history of hallucinogenic fish.

    Director:Unknown
    Writer:Unknown

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  20. Hamilton's Pharmacopeia Season 3 Episode 5 - Bufotenine: In Search of Hataj
    7.5/10(23 votes)

    #20 - Bufotenine: In Search of Hataj

    S3:E5

    Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

    Director:Unknown
    Writer:Unknown

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Best Episodes Summary

"Synthetic Toad Venom Machine" is the best rated episode of "Hamilton's Pharmacopeia". It scored 9.2/10 based on 47 votes. Directed by Unknown and written by Unknown, it aired on 1/4/2021. This episode scored 0.1 points higher than the second highest rated, "The Psychedelic Toad".