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The Worst Episodes of Hamilton's Pharmacopeia

Every episode of Hamilton's Pharmacopeia ranked from worst to best. Explore the Worst Episodes of Hamilton's Pharmacopeia!

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Join an incredible journey through the history, chemistry and societal impacts of the world’s most extraordinary drugs.

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Episode Rankings

  1. #1 Worst Episode
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    Hamilton's Pharmacopeia Season 3 Episode 5 - Bufotenine: In Search of Hataj
    7.5/10(23 votes)

    #1 - Bufotenine: In Search of Hataj

    S3:E5

    Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

    Director:Unknown
    Writer:Unknown

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  2. Hamilton's Pharmacopeia Season 1 Episode 5 - Fish N' Trips
    7.8/10(45 votes)

    #2 - Fish N' Trips

    S1:E5

    Hamilton embarks on an aquatic adventure to Reunion Island and Madagascar to investigate ichthyoallyeinotoxism and a twisted history of hallucinogenic fish.

    Director:Unknown
    Writer:Unknown

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  3. Hamilton's Pharmacopeia Season 3 Episode 4 - Synethetic Ibogaine-Natural Tramadol
    8.0/10(27 votes)

    #3 - Synethetic Ibogaine-Natural Tramadol

    S3:E4

    After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

    Director:Unknown
    Writer:Unknown

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  4. Hamilton's Pharmacopeia Season 3 Episode 3 - Xenon: the Perfect Anesthetic?
    8.2/10(27 votes)

    #4 - Xenon: the Perfect Anesthetic?

    S3:E3

    Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

    Director:Unknown
    Writer:Unknown

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  5. Hamilton's Pharmacopeia Season 2 Episode 3 - Kratom: The Forbidden Leaf
    8.4/10(53 votes)

    #5 - Kratom: The Forbidden Leaf

    S2:E3

    Hamilton investigates the pharmacology and traditional uses of Kratom, a Thai tree with opioid-containing leaves.

    Director:Unknown
    Writer:Unknown

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  6. Hamilton's Pharmacopeia Season 3 Episode 2 - A Positive Methamphetamine Story
    8.5/10(31 votes)

    #6 - A Positive Methamphetamine Story

    S3:E2

    From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs in order to understand the process behind a great American folk art.

    Director:Unknown
    Writer:Unknown

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  7. Hamilton's Pharmacopeia Season 3 Episode 6 - Ultra LSD
    8.5/10(28 votes)

    #7 - Ultra LSD

    S3:E6

    With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

    Director:Unknown
    Writer:Unknown

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  8. Hamilton's Pharmacopeia Season 1 Episode 2 - A Positive PCP Story
    8.6/10(61 votes)

    #8 - A Positive PCP Story

    S1:E2

    Hamilton investigates the history of PCP in the U.S., seeking input from addicts, dealers and chemists.

    Director:Unknown
    Writer:Unknown

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  9. Hamilton's Pharmacopeia Season 1 Episode 4 - Magic Mushrooms in Mexico
    8.6/10(61 votes)

    #9 - Magic Mushrooms in Mexico

    S1:E4

    Hamilton explores magic mushrooms with the help of shamans, clandestine growers, and ethnomycologists.

    Director:Unknown
    Writer:Unknown

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  10. Hamilton's Pharmacopeia Season 2 Episode 8 - The Cactus Apprentice
    8.6/10(41 votes)

    #10 - The Cactus Apprentice

    S2:E8

    Deep in the Andean highlands of Peru, Hamilton becomes the apprentice of a local shaman, learning how to use the night-blooming San Pedro cactus as a medicine.

    Director:Unknown
    Writer:Unknown

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  11. Hamilton's Pharmacopeia Season 2 Episode 5 - Ketamine: Realms and Realities
    8.7/10(65 votes)

    #11 - Ketamine: Realms and Realities

    S2:E5

    Hamilton heads to India to see industrial Ketamine synthesis, and speak with therapists and luminaries in an attempt to understand the role of dissociative anesthetics in society.

    Director:Unknown
    Writer:Unknown

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  12. Hamilton's Pharmacopeia Season 1 Episode 1 - The Story of the South African Quaalude
    8.8/10(74 votes)

    #12 - The Story of the South African Quaalude

    S1:E1

    South Africa is the last place on earth Quaaludes can still be found; Hamilton travels there to study the drug and learns of a dark history of medical experimentation.

    Director:Unknown
    Writer:Unknown

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  13. Hamilton's Pharmacopeia Season 2 Episode 2 - Peyote: The Divine Messenger
    8.8/10(59 votes)

    #13 - Peyote: The Divine Messenger

    S2:E2

    From the greenhouses of Thai cactophiles to the Tamaulipan thornscrub, Hamilton traces the history of peyote with the help of a Native American peyotist.

    Director:Unknown
    Writer:Unknown

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  14. Hamilton's Pharmacopeia Season 2 Episode 7 - A Fungal Fairy Tale
    8.8/10(49 votes)

    #14 - A Fungal Fairy Tale

    S2:E7

    Hamilton ascends the Carpathian Mountains, microscope in hand, to learn how Europeans use Amanita muscaria, and uncovers the chemistry behind a mushroom-inspired pharmaceutical.

    Director:Unknown
    Writer:Unknown

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  15. Hamilton's Pharmacopeia Season 1 Episode 3 - Shepherdess: The Story of Salvia Divinorium
    8.9/10(67 votes)

    #15 - Shepherdess: The Story of Salvia Divinorium

    S1:E3

    From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

    Director:Unknown
    Writer:Unknown

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  16. Hamilton's Pharmacopeia Season 2 Episode 4 - Wizards of DMT
    8.9/10(65 votes)

    #16 - Wizards of DMT

    S2:E4

    Hamilton travels across North America to study how and why DMT exists in the environment and the laboratory.

    Director:Unknown
    Writer:Unknown

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  17. Hamilton's Pharmacopeia Season 1 Episode 6 - The Lazy Lizard School of Hedonism
    9.0/10(65 votes)

    #17 - The Lazy Lizard School of Hedonism

    S1:E6

    We meet with famed LSD chemist Casey Hardison in the Nevada desert and embark on a roadtrip to visit the unsung hero of psychedelic history.

    Director:Unknown
    Writer:Unknown

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  18. Hamilton's Pharmacopeia Season 2 Episode 6 - A Clandestine Chemist's Tale
    9.0/10(60 votes)

    #18 - A Clandestine Chemist's Tale

    S2:E6

    Hamilton meets an unsung hero of the psychedelic underground and hears a tragic tale of MDMA synthesis and chemiluminescence.

    Director:Unknown
    Writer:Unknown

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  19. Hamilton's Pharmacopeia Season 2 Episode 1 - The Psychedelic Toad
    9.1/10(83 votes)

    #19 - The Psychedelic Toad

    S2:E1

    Hamilton embarks on a quest to answer the most important question in ethnoherpetological history and along the way, he finds the power of love.

    Director:Unknown
    Writer:Unknown

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  20. Hamilton's Pharmacopeia Season 3 Episode 1 - Synthetic Toad Venom Machine
    9.2/10(47 votes)

    #20 - Synthetic Toad Venom Machine

    S3:E1

    Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

    Director:Unknown
    Writer:Unknown

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Worst Episodes Summary

"Bufotenine: In Search of Hataj" is the worst rated episode of "Hamilton's Pharmacopeia". It scored 7.5/10 based on 23 votes. Directed by Unknown and written by Unknown, it aired on 2/1/2021. This episode scored 0.3 points lower than the second lowest rated, "Fish N' Trips".