Gina puts Connie in a difficult position when she asks her for help behind Elliot's back. Connie must then decide where her loyalties lie. Ric's skills are tested when he has to operate on an obese woman. Matt and Reg find more evidence of drug tampering.

Michael faces his appeal hearing, and uses the opportunity to try to patch things up with Connie, while Sam shares a secret with Chrissie. Lola discovers Leanne's father Steve has been admitted, and becomes convinced he is a drug user.

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Connie's heart battles her mind as she wonders if she should stay at Holby. Mark learns to respect the way Tricia wants to handle her cancer.

Lola must persuade a reluctant Ric to help her to gain custody of Leanne.

Matt tries to raise some money by signing up for clinical trials, after his landlord evicts him over unpaid rent , and Lola is angry when she receives a postcard from her globe-trotting daughter. Donna helps with a drugs audit, but ends up flirting with Bradley.

Tensions run high on Otter Ward when a major road traffic accident brings tragedy to one family as they face up to the death of their son, and joy to another as they are told that their daughter can have a long-awaited heart transplant. Meanwhile, Dr Taylor gets tough with Keri.

Mike Barratt considers a transfer to a hospital in New Zealand, to get away from the frustrations of the constraints on his work at Holby. New ward sister Chrissie Williams arrives, and gets off on the wrong foot by being rude to Jasmine Hopkins. One of Stan Ashleigh's schemes accidentally causes a widespread power cut in the hospital, interrupting operations, and trapping Anton Meyer in a service lift with James Campbell, who is becoming increasingly distraught over the death of his daughter, for which he holds the hospital staff responsible, despite Meyer's assurances and the conclusions of the in-house investigation. Victoria Merrick's murderer is identified.

Steve finds himself under pressure on the new AAU ward when a school trip ends in disaster. Jess gets more than she bargained for during her first day as a student nurse. Diane gets cold feet when Danny asks if he can move in.

Terry Fox proposes to Kath Shaughnessy, But changes his mind once Ric Griffin tells him he has terminal cancer. Marty Campbell-Gore comes back to Holby, which leads to a revelation for Tom, his brother. Bob Butler is admitted to Darwin Ward for a leg artery by-pass operation, but things turn out even worse than he and his wife feared. In Maternity, Mary Jenkins has triplets by Caesarian, but a serious problem with one of them is discovered soon after birth. A teenager who is sick of her mothers drug-dabbling antics, wants to be put into care after her mother is admitted with a dangerous reaction to an ecstacy tablet, which was supplied by Tom Campbell-Gore's dodgy brother Marty.

Holby is getting ready to See in the New Year, But Tom Campbell-Gore has returned to drink. When Ed Keating cathces him drinking before an operation, he stops Tom from operating. Kath and Terry Fox go to Terry's beach house, where Terry asks Kath to end His life, she does eventually and reluctantly accept. Danny Shaughnessy and Lisa Fox are caught in a clinch and Midnight and Chrissie Williams decides to keep her baby.

Alex refuses to take treatment for his tremor until he is persuade to by Diane who is back on her first day after her termination.

Mubbs was out to impress Rubinda who was on a placement shadowing Rosie. He showed off during an operation and put himself at risk of an HIV infection. Meanwhile, Owen asked Tricia to go on holiday and she accepted. Ric thought Kath's resignation was a mistake and reinstated her. However, when Sarah Palmer's father threatened to go to the papers, Ric backtracked and suggested Kath take some unused holiday. Jess was frozen to the spot when a reporter announced that Sandy had won £150,000 on the lottery. Sandy left Jess, Ric and Kelly large sums of cash and generously paid off Lisa's mortgage.Just as Nic decided to tell Sandy he loved her, he heard she'd dropped everything to be with Danny. Later, the staff gathered for drinks to wish their absent friend well in her new life in Australia and toasted ""the one and only Sandy.""

As the police invstigations into the suspicious deaths continues, Stan Ashleigh is admitted to Holby with heart problems. In theatre Ric Griffin and Diane Lloyd ignore his requested DNR.

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No description available

Lola discovers there is nothing wrong with asking for help. Mickie battles against rules and regulations only to find out that they are put there for a reason. Dean relises he can't put his personal pride before a patient.

Jess returns to work after the death of her son but finds her newfound determination put to the test when young patient Archie presents with a lacerated spleen and she suspects possible child abuse. Meanwhile, Mark tries to deal with the news that Chrissie is not his daughter.

Diane is told to work under Ric's supervision when she is blamed for Helen's death, but she is determined to clear her name and attempts to secretly record Nick confessing to his error. A new assistant general manager starts work at the hospital, and soon invites Donna to the May ball, while Matt gets a second job in the admin department to pay off his debts.

Bradley outlines his cost-cutting plans for the hospital, dividing opinions among the staff, especially when he suggests they could perform more operations to earn a £3million bonus. Joseph returns to the wards, but it is clear his OCD is not under control when he insists on scrubbing his hands repeatedly and fumbles a simple procedure.

Lola makes a drastic decision regarding baby Leeanne's care. Reg wonders if Bradley's intentions towards Donna are honourable. Jac works closely with Joseph.

Matt arrives for his first day in the hospital as a doctor, but soon realises how hard the role will be when he begins to suspect an elderly woman is being bullied by a foster child, while Elliot meets Gina when she arrives for an appointment. Reg becomes flustered when he sees Donna walking out of the staff shower, and grows increasingly jealous of her relationship with Bradley.

Meyer faces his greatest challenge when his surgical career is threatened by illness. Is he capable of operating on eminent surgeon and former teacher Ian Richards? Julie is forced to reassess her priorities when her daughter, Rosie, is taken seriously ill.

With her daughter's life in jeopardy, Julie believes that only Meyer can save her. But is Meyer up to the challenge? Stan and Danny set about putting on a show for the children in Otter ward.