Gina puts Connie in a difficult position when she asks her for help behind Elliot's back. Connie must then decide where her loyalties lie. Ric's skills are tested when he has to operate on an obese woman. Matt and Reg find more evidence of drug tampering.

Michael faces his appeal hearing, and uses the opportunity to try to patch things up with Connie, while Sam shares a secret with Chrissie. Lola discovers Leanne's father Steve has been admitted, and becomes convinced he is a drug user.

Matt tries to raise some money by signing up for clinical trials, after his landlord evicts him over unpaid rent , and Lola is angry when she receives a postcard from her globe-trotting daughter. Donna helps with a drugs audit, but ends up flirting with Bradley.

Diane is told to work under Ric's supervision when she is blamed for Helen's death, but she is determined to clear her name and attempts to secretly record Nick confessing to his error. A new assistant general manager starts work at the hospital, and soon invites Donna to the May ball, while Matt gets a second job in the admin department to pay off his debts.

Bradley outlines his cost-cutting plans for the hospital, dividing opinions among the staff, especially when he suggests they could perform more operations to earn a £3million bonus. Joseph returns to the wards, but it is clear his OCD is not under control when he insists on scrubbing his hands repeatedly and fumbles a simple procedure.

Lola makes a drastic decision regarding baby Leeanne's care. Reg wonders if Bradley's intentions towards Donna are honourable. Jac works closely with Joseph.

Connie's heart battles her mind as she wonders if she should stay at Holby. Mark learns to respect the way Tricia wants to handle her cancer.

As the police invstigations into the suspicious deaths continues, Stan Ashleigh is admitted to Holby with heart problems. In theatre Ric Griffin and Diane Lloyd ignore his requested DNR.

Fran returns to the hospital and takes some drastic action to try and get Jac's attention.

Elliot lets his personal feelings get the better of him when Gina is re-admitted. Sam is put on report but continues to do things on his own terms - will he learn his lesson?

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Philippa Calcutt, a woman with an advanced intestinal cancer, is visited by both a friend from church and her sister, who fears the friend is having an undue influence on her. On the children's ward is an 8-month-pregnant 15-year-old girl with an overbearing mother and a young boyfriend, Dean Flynn - Steve Waring's attempts at advice don't help smooth things for any of them. Samantha Kennedy holds a joint 30th birthday and flat-warming party, even summoning up the courage to invite Alex Adams, who declines. He in fact meets up with Jess Griffin, not knowing who she is, and awkwardly ends up at the party anyway. There, Steve gets into a brawl with an old school-friend Craig Campbell, resulting in a serious injury, and the calling of an ambulance and the police, who search Ric Griffin and find his considerable stash.

Jac's determination to have Ric choose her as the new consultant has tragic consequences. Sam bends the rules again and is brought down to earth with a bump. A determined Lola fights to keep Princess at home.

A woman comes in for a heart transplant, and Connie persuades her to accept an experimental procedure that has never been tried before. Ric leaves Nick in charge while he is at the university, but Jac does not approve of his handling of a cancer patient's treatment and a past conflict between them resurfaces.

Mark gets over involved in a case which causes disastrous consequences. Meanwhile, Nick Jordan rocks Diane's world which may affect her relationship with Ric.

Matt's parents want him discharged from hospital to be treated at home, while Mark blames himself for the stabbing. Donna flirts with a handsome physiotherapist, though Kyla warns her to stay away from him. The treatment of a heart patient causes conflict, as Connie wants to try the manufactured pump she helped develop, but Elliot is adamant a transplant is required.

Sahira is torn between the two men in her life, while Ric clashes with Hanssen.

When the police realise that Nic couldn't have been the murderer, he is released. Meanwhile, Rosies daughter is admitted to AAU after overdosing on her mother's iron tablets.

Connie is devastated when her patient collapses and there's not enough time to arrange a heart transplant. Nick tries to get Diane on his side by letting her perform a difficult procedure for the first time, while Ric talks her into taking the research position full time. Kyla brings Max to work as he is a diabetic and she is worried about his blood sugar levels.

Jordan helps Connie save the day when a black tie charity dinner turns into a disaster zone. In an attempt to ingratiate himself with Kyla, Justin offers to look after Max.

Elliot's Ukrainian trip takes a twist when he discovers the real reason for his visit.

Terry Fox proposes to Kath Shaughnessy, But changes his mind once Ric Griffin tells him he has terminal cancer. Marty Campbell-Gore comes back to Holby, which leads to a revelation for Tom, his brother. Bob Butler is admitted to Darwin Ward for a leg artery by-pass operation, but things turn out even worse than he and his wife feared. In Maternity, Mary Jenkins has triplets by Caesarian, but a serious problem with one of them is discovered soon after birth. A teenager who is sick of her mothers drug-dabbling antics, wants to be put into care after her mother is admitted with a dangerous reaction to an ecstacy tablet, which was supplied by Tom Campbell-Gore's dodgy brother Marty.

Alex Adams feels more deppressed about his Parkinsons when he attends his father's funeral and meets his estranged family.

Chrissie finaly finds out about the relatioship between Owen and her mother and after a fight between the two, they both get suspended. As the police investigations continue a forensic psychologist is brought in to interrogate the murder suspects.

Nic and Kelly's mother is admitted with severe stab wounds and Nic thinks Kelly is responsible. Kelly promises that she will hand herself in to the police but later she trie to kill her mother again. Kath interrupts her and she chases her through the hospital until they are in a room alone together and Kelly stabs Kath.