As the police invstigations into the suspicious deaths continues, Stan Ashleigh is admitted to Holby with heart problems. In theatre Ric Griffin and Diane Lloyd ignore his requested DNR.

When the police realise that Nic couldn't have been the murderer, he is released. Meanwhile, Rosies daughter is admitted to AAU after overdosing on her mother's iron tablets.

Chrissie finaly finds out about the relatioship between Owen and her mother and after a fight between the two, they both get suspended. As the police investigations continue a forensic psychologist is brought in to interrogate the murder suspects.

Nic and Kelly's mother is admitted with severe stab wounds and Nic thinks Kelly is responsible. Kelly promises that she will hand herself in to the police but later she trie to kill her mother again. Kath interrupts her and she chases her through the hospital until they are in a room alone together and Kelly stabs Kath.

As Jess and Kelly go to visit Nic at the police station, Ric tries to hide his gambling debts and the fact that his home has been repossessed.

As Nic's condition worsens, he asks to see his sister before she is moved to a secure hospital. When he deteriorates he must be taken to theatre but cannot be saved.

George's condition pushes Ed and Tom's professional relationship to the brink. And Rick and Diane get close over a case.

When Mubbs considers leaving his job, Rosie tells him that she loves him. Tom performs an operation on a high risk patient against Zubins wishes and a woman has a miscarriage which Mubbs discovers is because of her condition.

Tom and Ed treat young woman with a strangely high blood pressure and heart problem and Robert Pullman is readmitted with a bicycle accident injury but Ric doesn't belive him.

As DI Jane Archer investigates the recent deaths on Keller, Ric gambles away a small fortune to try and repair his relationship with his daughter. A patient is brought in who needs a gall-bladder operation desperately which has to be done at the Hadlington but her husband hasn't told her that they can't afford it.

Ric is served with a reposession notice as he gambles away more od his money and Nic Yorke is still being held at the police station for the murder of two.

Having lost his home, Ric Griffin has been sleeping in his office.

Jess finds out that her father has been sleeping in his office and she insists that he stays with her. Ric defends Kath from the board who want to suspend her and she is arrested.

Kelly wants Nic to run away with her, she finaly tells him the truth.

Zubin Khan finds Kath bleeding to death in a room and Nic's mother finaly confesses to him.

There's a dramatic start to the festive season in Holby following the gas explosion, which has left siblings Nic and Kelly fighting for their lives. The pair are rushed into hospital, where Jess keeps a vigil by Nic's bedside, while Kelly is rushed into theatre—and for Ric, who knows his colleague is a deranged murderess, this proves a real test of his professionalism, as he resists the temptation to just let her die. On a lighter note, Tom hosts the Holby Christmas bash, where an inebriated Tricia makes a complete spectacle of herself, while ladies' man Mubbs surprisingly opts to give the party a miss and do a spot of babysitting for Rosie instead.

Chrissie and Mubbs wake up together after their one night stand and Ed Keating finds out that his father will be released in a few weeks.

Ric performs a very high risk operation on a cancer patient and Diane thinks that it is for money. She decides to tell Tom about it and Ric is left feeling betrayed by her. Ric later reveals to Zubin that he took on the risk for kicks.

After gambling with the life if a patient, Zubin asks Ric to see a psychyatrist. Jess considers not going to Nic Yorke's funeral.

At Nic's funeral Jess is the only person from the hospital to be there. Nic's mother and a depressed Kelly are also there. Jess visits Kelly after the funeral but it doesn't go very well. When she returns, she receives the news that Kelly hanged herself and she is dead.

After a bad day for Tricia and Kath, Tricia invites Diane and Kath to the bar to get drunk. In maternity a young pregnant woman wants to give her baby for adoption immediately despite the fathers opinion.

Tom and Ed are caught in a dilemma over a transplant, whilst Rosie fears that her relationship with Mubbs has alienated her children. A quirky but handsome new arrival brightens Kath's day.

A shock admission to Darwin finds Chrissie struggling to keep a secret from Ed, and Ric has some surprising news for Jess.

The custody battle draws near for Rosie. Ed could face Tom's wrath once more. Alarm bells ring for Diane as she talks to a young girl and her father.

Mubbs discovers where he really stands with Rosie. Ed throws out the rule book for his dad. And Diane is working with her new flame.