With the rest of the team racing to stop an illicit weapons sale, Rex resolves to bring justice all on his own when he witnesses a murder while stuck at home.

When a murder investigation devolves into a kidnapping, Rex's nose leads him and Charlie to Bell Island, and right into the middle of a double murder plot.

Charlie and Rex try to take down a car theft ring after one of the team is seriously injured trying to stop a theft in progress.

Detective Charlie Hudson teams up with what he calls his "highly trained law enforcement animal" German Shepherd dog named Rex who he prefers to team up with because he doesn't talk his ear off.

When two hikers are discovered murdered near a remote coastal trail, the team is on the hunt for a fugitive duo wanted in a series of grisly campsite murders.

On the trail of a serial arsonist, Charlie is hospitalized after a brush with a bombing breaks his leg. Unable to let the case rest through his recovery, Charlie works the evidence from his bed, hoping to identify the arsonist

On the third anniversary of Charlie and Rex's partnership, Charlie recounts how a high-stakes kidnapping brought the duo together on their first case.

While Sarah embarks on a wilderness adventure, Charlie and Rex investigate the murder of a college professor.

After a truck transporting liquid explosive is hijacked by criminals, Charlie and Rex find themselves in a race against time to prevent the case from blowing sky high.

As Major Crimes investigates a dark web marketplace, Charlie and Rex protect a witness in their home.

The Major Crimes team is forced to turn against Jesse when he becomes the prime suspect in a bank robbery.

Charlie and Rex receive an award for heroism while Major Crimes investigates an extremist threat.

Charlie, Rex and Sarah travel to an isolated island community caught up in a resettlement dispute. Donovan tries to stop a British police officer from derailing the investigation.

While St. John's celebrates Mardi Gras, Charlie and Rex investigate a targeted killing spree.

When Officer Maya Power and her K9 partner Rebel are violently attacked responding to a call about a warehouse break-in, Major Crimes is at the ready.

Charlie and Rex investigate the murder of a wealthy man who leaves only his three dogs to his estranged friends.

Charlie and Rex discover a wanted criminal has been living in St. John's under a false identity for twenty years and end up in the crosshairs when the man's past catches up with him.

Rex is on trial after his DNA is discovered at the scene of the murder of Donovan's former police informant.

Rex seeks help from Detective Sidney Scott to save his stranded and injured friends.

Charlie and Rex sniff out the suspects when the Chief Superintendent of the St. John's Police Department dies at a popular restaurant and all signs point to poison.

When a body is found in a shipping container, Charlie teams up with a female cop from his past to solve the crime, Rex is not a fan and keeps getting between the two, keeping the path clear for Charlie and Sarah.

As Charlie and Rex head into the woods to track a missing photographer, a mysterious organization throws the investigation off its trail.

Cultures clash when the death of a Parisian journalist has Charlie and Rex partnering with a French detective, in an investigation that whisks the team to Saint Pierre and Miquelon.

Charlie and Rex follow the route of a killer after a tech engineer is found dead in her company's self-driving car.

When a prominent member of an exclusive dating app is found with an arrow through his heart, Charlie is forced to go undercover in the online dating scene.