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The Best Episodes of Mystery Diagnosis

Every episode of Mystery Diagnosis ranked from best to worst. Let's dive into the Best Episodes of Mystery Diagnosis!

The Best Episodes of Mystery Diagnosis

Mystery Diagnosis is a television program that airs on the OWN: Oprah Winfrey Network. Each episode focuses on two or more individuals and their struggles...
  1. Background image for Deadly Sore Throat
    9.0/10(5 votes)

    #1 - Deadly Sore Throat

    S3:E3

    A man suffers from a series of debilitating symptoms; doctors cannot diagnose his illness, but thanks to a chance meeting this mystery will be solved; a woman undergoes a risky left temporal craniotomy.

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    Director:Unknown
    Writer:Unknown
  2. Background image for The 13 Year Stomach Ache
    9.0/10(6 votes)

    #2 - The 13 Year Stomach Ache

    S3:E4

    A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

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    Director:Unknown
    Writer:Unknown
  3. Background image for The Bearded Lady
    9.0/10(5 votes)

    #3 - The Bearded Lady

    S3:E5

    A woman and her husband decide to start a family after numerous negative pregnancy tests; a man appears to suffer an embolism

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    Director:Unknown
    Writer:Unknown
  4. Background image for The Toddler That Went Through Puberty
    8.9/10(7 votes)

    #4 - The Toddler That Went Through Puberty

    S9:E7

    A three-year-old's unexplained vaginal bleeding sends her parents searching for answers to help their baby girl. Also, a student plagued by cramps is unable to hold her food down.

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    Director:Unknown
    Writer:Unknown
  5. Background image for Blood & Fire
    8.8/10(5 votes)

    #5 - Blood & Fire

    S1:E6

    A 12-year-old girl experiences abdominal pains and severe headaches until she is diagnosed with a retroflexed odontoid and Chiari One malformation; a firefighter and paramedic is diagnosed with acquired immunodeficiency syndrome (AIDS).

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    Director:Unknown
    Writer:Unknown
  6. Background image for The Boy Who Couldn't Breathe
    8.8/10(5 votes)

    #6 - The Boy Who Couldn't Breathe

    S3:E6

    A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

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    Director:Unknown
    Writer:Unknown
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  8. Background image for The Toddler That Stopped Walking
    8.8/10(9 votes)

    #7 - The Toddler That Stopped Walking

    S9:E8

    A mother rushes her toddler to hospital when she loses the ability to walk or stand. Plus, a runner tries to sleep off a numbness in his foot, but finds the sensation spreading.

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    Director:Unknown
    Writer:Unknown
  9. Background image for A Family's Desperate Search
    8.8/10(5 votes)

    #8 - A Family's Desperate Search

    S10:E5

    Since birth, Ricky is plagued by respiratory infections and a bizarre inability to grow. Noel is a healthy, active man until mysterious spasms start taking over his life.

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    Director:Unknown
    Writer:Unknown
  10. Background image for Too Young To Be Sick
    8.7/10(6 votes)

    #9 - Too Young To Be Sick

    S10:E7

    Harry's body starts to undergo a mysterious transformation. Sadie finds herself on the brink of starvation after her doctor dismisses her complaints.

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    Director:Unknown
    Writer:Unknown
  11. Background image for The Baby Who Changed Colors
    8.6/10(5 votes)

    #10 - The Baby Who Changed Colors

    S3:E8

    Brenda and Jake are delighted when their daughter Isabel is born, but their euphoria quickly turns to panic when Isabel stops eating and her skin turns grey. Noah and Alexis were healthy twins until they suddenly lost all their milestones. Charlie, an active pastor, has difficulty reading; doctors must act quickly to save his eyesight.

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    Director:Unknown
    Writer:Unknown
  12. Background image for When the Body Shuts Down
    8.6/10(5 votes)

    #11 - When the Body Shuts Down

    S10:E4

    When Kylie is born struggling to breathe, doctors aren't sure whether they will find a cure. Also, athlete Michael is left fighting for his life when a sore throat turns deadly.

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    Director:Unknown
    Writer:Unknown
  13. Background image for The Boy Who Kept Swelling
    8.4/10(7 votes)

    #12 - The Boy Who Kept Swelling

    S6:E6

    An 18-month-old baby suddenly starts screaming one afternoon in the pool, and begins exhibiting extremely painful symptoms when exposed to sunlight, with porphyria later found to be the culprit. A mother of two children begins to suffer a series of very debilitating headaches.

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    Director:Unknown
    Writer:Unknown
  14. Background image for The Woman Whose Legs Turned Black
    8.3/10(6 votes)

    #13 - The Woman Whose Legs Turned Black

    S8:E1

    Diane finds two small, red bumps on her foot; within hours her foot is swollen and appears black and blue; despite undergoing tests, the medical team has no diagnosis.

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    Director:Unknown
    Writer:Unknown
  15. Background image for The Boy Who Couldn't Stop Eating
    8.3/10(6 votes)

    #14 - The Boy Who Couldn't Stop Eating

    S8:E3

    After blisters appear all over the body of young Julie McCawley, she appears to have Stevens-Johnson syndrome; Conor Heybach's weight gain and uncontrollable appetite is a mystery until a doctor discovers he has Prader-Willi syndrome.

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    Director:Unknown
    Writer:Unknown
  16. Background image for The Boy Who Only Hopped
    8.3/10(6 votes)

    #15 - The Boy Who Only Hopped

    S9:E2

    After moving houses, and months of strange behavior, 12-year-old Sammy stops walking and only hops; the doctors are the only hope to discover the cause of his bizarre symptoms. He is eventually diagnosed with PANDAS, a condition in which antibodies mistake his brain for Streptococcus bacteria.

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    Director:Unknown
    Writer:Unknown
  17. Background image for The Girl With No Bowel
    8.2/10(5 votes)

    #16 - The Girl With No Bowel

    S9:E5

    After suffering a series of debilitating incidents believed to be the result of Crohn's disease, Karen, an albino, has to have most of her colon removed. Several decades later, at the age of 38, she receives a phone call from someone who suggests she is suffering from a rare and fatal disease, Hermansky-Pudlak syndrome, which is also the cause of her albinism.

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    Director:Unknown
    Writer:Unknown
  18. Background image for Sleeping Beauty
    8.0/10(6 votes)

    #17 - Sleeping Beauty

    S3:E1

    A girl sleeps for ten days in a row, but tests are normal and doctors are perplexed; a marathon runner experiences unexplainable fatigue.

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    Director:Unknown
    Writer:Unknown
  19. Background image for The Woman Whose Flesh Was Eaten Alive
    8.0/10(5 votes)

    #18 - The Woman Whose Flesh Was Eaten Alive

    S9:E1

    June has a biopsy and, when a mark appears on the site, she has surgery, leaving her with a growing open wound. Her doctor diagnoses her with a flesh eating virus. Can June's life be saved?

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    Director:Unknown
    Writer:Unknown
  20. Background image for The Woman With Unusual DNA
    8.0/10(7 votes)

    #19 - The Woman With Unusual DNA

    S9:E9

    When Jeanne fails to hit puberty, doctors discover that something truly bizarre is the cause; analysis of her DNA finds that she is genetically male, possessing Y chromosomes, but due to the rare genetic disorder Swyer syndrome, she appears outwardly female. Mary is stricken with a collapsed lung and breathing problems.

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    Director:Unknown
    Writer:Unknown
  21. Background image for Why Is Emily Screaming?
    7.8/10(5 votes)

    #20 - Why Is Emily Screaming?

    S1:E5

    A baby who cries and holds her cheek; a woman who gained 100 pounds in three months and developed severe acne; and an avid athlete struggling to catch his breath. Featuring trigeminal neuralgia, polycystic ovary syndrome and alpha-1 antitrypsin deficiency.

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    Director:Unknown
    Writer:Unknown
  22. Background image for The Woman Who Couldn't Stop Rocking
    7.8/10(5 votes)

    #21 - The Woman Who Couldn't Stop Rocking

    S6:E2

    A woman starts failing after a family vacation; another woman, who has suffered from stomach pains for years, has problems with swelling during menstruation.

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    Director:Unknown
    Writer:Unknown
  23. Background image for The Boy Who Stopped Walking
    7.8/10(6 votes)

    #22 - The Boy Who Stopped Walking

    S6:E7

    Rachele Lacount and Mike West are delighted that their baby has started to walk and talk, but suddenly they realize that something is wrong with his right eye. Since middle school, Cherryl Marshall struggled with taming her obscene body odor.

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    Director:Unknown
    Writer:Unknown
  24. Background image for The Boy Who Bit Himself
    7.8/10(6 votes)

    #23 - The Boy Who Bit Himself

    S6:E8

    Parents notice their 7-month-old son has troubling physical impairments, then begins violently harming himself, culminating in a horrifying incident where the child bites off his own lower lip; he is later diagnosed with the genetic condition Lesch-Nyhan syndrome. A woman traveling the world starts experiencing unusual back pain and tingling in her feet that rapidly develops into a spreading paralysis; following the successful use of plasmapheresis, the cause of the dangerous condition is identified as Devic's disease, an inflammation of the spinal cord.

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    Director:Unknown
    Writer:Unknown
  25. Background image for The Girl With Half a Face
    7.8/10(6 votes)

    #24 - The Girl With Half a Face

    S7:E7

    Nicole is a teenager who feels excruciating pain in her jaw and her face starts to sink, with her affliction later found to be the result of Parry-Romberg syndrome. Kevin thinks he has food poisoning, but he starts to lose motor coordination.

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    Director:Unknown
    Writer:Unknown
  26. Background image for The Man Who Tripled in Size
    7.8/10(5 votes)

    #25 - The Man Who Tripled in Size

    S8:E2

    Walt has always been in good health until one day he suddenly faints; when he arrives at hospital, his blood pressure is very low and he has gained 100 lb (45 kg) of weight in water. It is eventually discovered that he is suffering from systemic capillary leak syndrome.

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    Director:Unknown
    Writer:Unknown

Best Episodes Summary

"Deadly Sore Throat" is the best rated episode of "Mystery Diagnosis". It scored 9/10 based on 5 votes. Directed by Unknown and written by Unknown, it aired on 4/23/2007. This episode scored 0.0 points higher than the second highest rated, "The 13 Year Stomach Ache".